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Background: Individuals with diabetes (DM) are often treated with statins, which have a rare side effect: peripheral neuropathy. We aimed to study whether statin treatment affects the risk of carpal tunnel syndrome (CTS) and ulnar nerve entrapment (UNE) in type 2 DM (T2DM). Methods: We combined multiple national registers in Sweden to identify individuals diagnosed with CTS or UNE in specialized c
Road traffic pollution is one of the most important factors among other environmental factors that influence the roadside vegetation. The present research examines the impact of motorway flyovers and at-grade roads on air pollution (PM10, SOx, NOx, and air quality index (AQI)) and roadside vegetation in Dehradun by considering the important biochemical parameters such as chlorophyll, ascorbic acid
The use and significance of timber structures are on the rise, especially thanks to crosslaminated timber (CLT). This engineered wood product is manufactured by stacking multiple layers of wood lamellae, each oriented perpendicularly to the one below it, and then bonding them with adhesives to form a floor or wall panel. Timber, as a building material, presents potential environmental benefits ove
Background: The Indian food industry is undergoing a significant shift towards sustainability, driven by emerging technologies such as artificial intelligence (AI). This study aims to explore the role of AI in promoting sustainable food processing in India, based on data collected from 110 businesses. Methods: Three hypotheses were developed and analyzed to assess the adoption of AI for sustainabi
Poultry industry worldwide: Newcastle Disease (ND) is highly contagious poultry viral disease posed a major threat to the poultry industry due to millions of deaths worldwide. Newcastle Disease Virus (NDV) cause recurrent epidemics due to its rapid genomic evolution. In this study, we developed an in silico vaccine against all NDV strains using matrix protein. A reverse vaccinology approach was em
Background: Three-quarters of all mental health problems begins between 10-24 years. When not treated, adolescents and young people with mental health problems are at high risk of abuse, suicide, and substance use, which have long-term consequences that negatively impact physical, and economic productivity. The study aimed to determine the prevalence of mental health problems among secondary schoo
Objective Obesity is a well-known risk factor for coronary heart disease (CHD), but there is little evidence on the effect of long-term trajectories of body mass index (BMI) over the life course. By using repeated assessments, the aim was to study the risk of CHD in adults during 38 years in different trajectories of BMI. Methods A sample of 2129 men and women, aged 20-59 years at baseline, took p
Members of the Chlamydiales order all share a biphasic lifecycle alternating between small infectious particles, the elementary bodies (EBs) and larger intracellular forms able to replicate, the reticulate bodies. Whereas the classical Chlamydia usually harbours round-shaped EBs, some members of the Chlamydia-related families display crescent and star-shaped morphologies by electron microscopy. To
Background: Dysphagia, which can result in aspiration pneumonia and death, is a well-known problem in patients with dementia and Parkinson's disease. There are few studies on dysphagia in patients with dementia with Lewy bodies (DLB) and Parkinson's disease dementia (PDD), especially studies objectively documenting the type of swallowing dysfunction. The aim of this study was therefore to investig
Popular Abstract in Swedish Hjärt och kärlsjukdomar utgör idag den vanligaste orsaken till död världen över. I denna avhandling studerades patienter med hjärt-kärlsjukdom inom svenska register för att analysera betydelsen av olika komponenter av behandlingen vid hjärt-kärlsjukdom. Komponenter som utvärderades var tid till primär perkutan (endovaskulär) kranskärlsintervention (PCI), dvs ballongvidgIntroduction: Ischemic heart disease is the leading cause of death worldwide. The aims of this thesis were to evaluate different contemporary approaches in coronary care with regard to mortality and myocardial infarction. Methods: The thesis consists of 6 papers with 4 papers evaluating different exposures and their outcomes (clopidogrel pre-treatment, 5 different anti-platelet protocols, ticagrel
Background: Hip dislocation is a serious complication among children with cerebral palsy (CP). The aim of this study was to compare the prevalence of hip dislocation among children with CP in an area providing regular care with an area providing hip surveillance services. Methods: This is a cross-sectional study in seven Norwegian counties providing regular care and one Swedish healthcare region w
Introduction: Cadmium (Cd) is toxic to the kidney and a major part of the body burden occurs here. Cd in urine (U-Cd) and blood (B-Cd) are widely-used biomarkers for assessing Cd exposure or body burden. However, empirical general population data on the relationship between Cd in kidney (K-Cd), urine, and blood are scarce. Our objectives were to determine the relationship between cadmium in kidney
Aim. - To explore the association between baseline levels of insulin-like growth-factor-binding protein-1 (IGFBP-1), a marker of insulin sensitivity, and the development of type 2 diabetes or impaired glucose tolerance (IGT) in a specifically defined middle-aged population. Methods. - This cross-sectional population-based screening study was conducted in 1989-1990 and included baseline data for 66
Several zooplankton species are susceptible to ultraviolet radiation (UV), suggesting that UV may shape zooplankton community composition. Little is known, however, about the quantitative effects of long-term UV exposure in relation to biological processes. Therefore, we studied effects of UV on behaviour, population dynamics and reproduction of several zooplankton taxa. We identified different st
We have studied the growth of doped InAsyP1-y (InAsP) NWs and InAsP-InP core-shell NWs. Using hydrogen chloride (HCl) we were able to prevent radial growth on the InAsP NWs. Undoped and H2S-doped InAsP NWs had almost pure wurtzite crystal structure, while DEZn-doped NWs showed wurtzite periodically separated by short sections of pure zincblende with rotational twins. Electrical measurements confir
BACKGROUND: Radiostereometric analysis (RSA) is often used for evaluating implanted devices over time. Following patients who have had tantalum beads implanted as markers in conjunction with joint replacements is important for longitudinal evaluation of these patients and for those with similar implants. As doing traditional RSA imaging is exacting and limited to specialized centers, it is import
AIM: We assessed prevalence and location of pain in a total population of children and adolescents with cerebral palsy (CP) based on the Gross Motor Function Classification System (GMFCS), age and gender. METHODS: This cross-sectional study was based on the last assessment of children aged 1-14 years in the combined Swedish follow-up programme and national quality register programme for CP. All
The known breast cancer susceptibility polymorphisms in FGFR2, TNRC9/TOX3, MAP3K1, LSP1, and 2q35 confer increased risks of breast cancer for BRCA1 or BRCA2 mutation carriers. We evaluated the associations of 3 additional single nucleotide polymorphisms (SNPs), rs4973768 in SLC4A7/NEK10, rs6504950 in STXBP4/COX11, and rs10941679 at 5p12, and reanalyzed the previous associations using additional ca
Reclamation on bare tailing ponds has the potential to represent soil genesis in Technosols favoring the understanding of the changes of microbial communities and function. In this study we used phytostabilization aided with calcium carbonate and pig slurry/manure to reclaim an acidic bare tailing pond with the aim of investigating the effect of amending and different species on microbial communit
