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BackgroundIron deficiency is a common and undertreated problem in inflammatory bowel disease (IBD). AimTo develop an online tool to support treatment choice at the patient-specific level. MethodsUsing the RAND/UCLA Appropriateness Method (RUAM), a European expert panel assessed the appropriateness of treatment regimens for a variety of clinical scenarios in patients with non-anaemic iron deficienc
AIM: We assessed prevalence and location of pain in a total population of children and adolescents with cerebral palsy (CP) based on the Gross Motor Function Classification System (GMFCS), age and gender. METHODS: This cross-sectional study was based on the last assessment of children aged 1-14 years in the combined Swedish follow-up programme and national quality register programme for CP. All
The known breast cancer susceptibility polymorphisms in FGFR2, TNRC9/TOX3, MAP3K1, LSP1, and 2q35 confer increased risks of breast cancer for BRCA1 or BRCA2 mutation carriers. We evaluated the associations of 3 additional single nucleotide polymorphisms (SNPs), rs4973768 in SLC4A7/NEK10, rs6504950 in STXBP4/COX11, and rs10941679 at 5p12, and reanalyzed the previous associations using additional ca
Reclamation on bare tailing ponds has the potential to represent soil genesis in Technosols favoring the understanding of the changes of microbial communities and function. In this study we used phytostabilization aided with calcium carbonate and pig slurry/manure to reclaim an acidic bare tailing pond with the aim of investigating the effect of amending and different species on microbial communit
Studies on fetal lung/brain circulation by means of power Doppler technique have suggested a marked reduction in lung perfusion in high-risk pregnancies as a sign of circulation redistribution. The ratio between lung/brain perfusion might therefore give a new method to predict fetal circulation centralization. Objective: The aim of the present study was to obtain fetal lung and cerebral artery rat
Immunotherapy of malignant primary brain tumors holds the potential to improve the dismal prognosis after current clinical therapy. Although immunotherapy of experimental gliomas has been demonstrated to have the capacity to cure intracerebral tumors no convincing effects of immunotherapy have been shown in clinical trials. One reason for this could be that some of the models used do not display f
Soil moisture induced droughts are expected to become more frequent under future global climate change. Precipitation has been previously assumed to be mainly responsible for variability in summer soil moisture. However, little is known about the impacts of precipitation frequency on summer soil moisture, either interannually or spatially. To better understand the temporal and spatial drivers of s
Scabies is a parasitic infestation of the skin by the mite Sarcoptes scabiei that causes significant morbidity worldwide, in particular within socially disadvantaged populations. In order to identify mechanisms that enable the scabies mite to evade human immune defenses, we have studied molecules associated with proteolytic systems in the mite, including two novel scabies mite serine protease inhi
Autoantibodies against glutamic acid decarboxylase (GAD65Ab) are used in the classification of diabetes in adults. We assessed the concordance in GAD65 autoantibody levels within subjects between three different GAD65Ab radio binding assays (RBA). Plasma samples from 112 diabetes patients (median age 50 years) initially classified with type 2 diabetes was randomly selected from a local diabetes re
Objective. This study aimed to assess self-reported well-being in a clinical sample of stroke patients and to identify possible associations with prevalence, severity and bother of lower urinary tract symptoms (LUTS). Material and methods. A cross-sectional, clinical survey was initiated whereby stroke patients were invited to complete The WHO-Five Well-Being Index (WHO-5) and a LUTS instrument, t
Context: This review focuses on the prevention and management of complications following radical cystectomy (RC) for bladder cancer (BCa). Objective: We review the current literature and perform an analysis of the frequency, treatment, and prevention of complications related to RC for BCa. Evidence acquisition: A Medline search was conducted to identify original articles, reviews, and editorials a
Background: A strong association has been shown between high viral DNA load (VL) of human papillomavirus (HPV) type 16 and risk for cervical cancer in situ (CIS). However, little data is available for the significance of VL in invasive squamous cell carcinoma (SCC). Methods: In 2 nested case-control studies among women participating in cervical screening, with a cytologically normal first smear, w
Background: Negative pressure wound therapy (NPWT) has remarkable effects on the healing of poststernotomy mediastinitis. Foam is presently the material of choice for NPWT in this indication. There is now increasing interest in using gauze, as this has proven successful in the treatment of peripheral wounds. It is important to determine the effects of NPWT using gauze on heart pumping function bef
Background and purpose Spasticity and muscle contracture are two common manifestations of cerebral palsy (CP). A spastic muscle may inhibit growth in length of the muscle, but the importance of this relationship is not known. In 1994, a register and a healthcare program for children with CP in southern Sweden were initiated. The child's muscle tone according to the Ashworth scale and the ankle ran
Objective. The enteric microbiota is a pivotal factor in the development of intestinal inflammation in humans but probiotics, dietary fibres and phytochemicals can have anti-inflammatory effects. The aim of this study was to evaluate the therapeutic effect of multi-strain probiotics and two conceivable prebiotics in an experimental colitis model. Material and methods. Sprague-Dawley rats were fed
Denna studie ämnade att undersöka effekten av anisktsattraktivitet på rekryterares bedömning av arbetssökandes kompetens (hårda och mjuka färdigheter) samt anställningsbarhet. Det undersöktes också om betydelsen av attraktivitet skiljer sig mellan män och kvinnor i dessa sammanhang. För undersökningen konstruerades en enkät som inleddes med ett fiktivt personligt brev och en ansiktsbild på den “söThis study aimed to examine the effect of facial attractiveness on recruiters’ assessment of applicants' competence (i.e., hard and soft skills) and employability. It also examined if the importance of attractiveness differs between men and women in these contexts. A survey was constructed that began with a fictitious cover letter and a face photo of the “applicant”. While the letter was the s
Purpose of the study: To further generate an understanding of previous research on NSD challenges in small firms and NSD methods used by firms when developing new experiential services. Theory: Research on challenges faced by small firms with performing NSD and methods experiential service firms use to perform NSD. Methodology: Qualitative multiple case study, the study is deductive in nature. Dat
The aim of the study is to research upper secondary teachers’ attitudes towards, and use of, critical perspectives in teaching literature in the subject of English in Sweden. This is done in relation to the inequality issues identified in the Swedish school context, the Swedish National Curriculum for the Upper Secondary School and the syllabi for English, along with a theoretical framework based
Quark is a dairy product that has existed for a long time. However, it has grown in popularity during the last years due to the fact that it is often portrayed as a healthy alternative in the dairy section. There are no regulations connected to the manufacturing process of quark. At a specific dairy company, there is a desire to understand and optimise the quark production to obtain a consistently
Chronic obstructive pulmonary disease (COPD) is currently the third leading cause of death worldwide and for patients with end-stage disease, the only viable treatment is lung transplantation. In order to meet this clinical need, novel approaches of tissue engineering have emerged. 3D bioprinting technologies are one such rapidly evolving approach and show promising results in terms of biocompatib
