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European emission legislation has in recent years put a strict limit on NOx emissionsfrom heavy-duty truck engines. EGR and selective catalytic reduction are the two mostcommon technologies applied in a modern heavy-duty diesel engine to fulfill the legislation.The scope of this thesis is to explore other ways of reducing NOx emissions emittedby a heavy-duty engine. Several technology options are
Purpose: To characterize the effects of water T2 relaxation time in the glycosaminoglycan chemical exchange saturation transfer method (gagCEST) and compare them between 3T and 7T as well as between various saturation schemes. Methods: Simulations and a phantom experiment were conducted at 3T and 7T in a range of water T2 values and GAG concentrations using various saturation schemes. For both sim
The “wooded-meadows system” is a multifunctional use of vegetation resources widespread in Europesince the Neolithic, and well documented in the Ligurian Apennines (NW Italy) between the MiddleAges and the first half of the 19th century. The management of wooded-meadows included: collectionof fallen and dead branches in spring, later used for fuel; mowing and grazing in summer; collection ofsecond
Background: Recent years of research have increased the knowledge about how to support the transition to adulthood for youths with disabilities. In today’s multi-cultural societies knowledge about transitioning immigrant youths and their caregivers is still needed.Objective: To describe the expectations and needs of immigrant youths with disabilities residing in Sweden during their transition into
Eighty-three patients with high risk ocular hypertension were followed between 9 and 120 months with computerized threshold perimetry every three months in a prospective clinical study. Twenty eyes developed definite glaucomatous visual field defects. Analysis of these cases showed that definite field loss was preceded by increased variability of measured threshold values. Already at this early st
Changes in vegetation phenology are among the most sensitive biological responses to global change. While land surface phenological changes in the Northern Hemisphere have been extensively studied from the widely used long-term AVHRR (Advanced Very High Resolution Radiometer) data, current knowledge on land surface phenological trends and the associated drivers remains uncertain for the tropics. T
Complications of diabetes include sensory and autonomic neuropathy. The aim of the present paper was to study the degree of sensory and autonomic neuropathy and correlate these findings with the distribution and density of neuropeptidergic nerve fibers in the skin of the forearm of diabetic patients and healthy controls. We investigated 30 diabetics (24 type 1 and 6 type 2) and compared them with
The quasi-free scattering reactions 11C(p,2p) and 10,11,12C(p,pn) have been studied in inverse kinematics at beam energies of 300–400 MeV/u at the R3B-LAND setup. The outgoing proton-proton and proton-neutron pairs were detected in coincidence with the reaction fragments in kinematically complete measurements. The efficiency to detect these pairs has been obtained from GEANT4 simulations which wer
Calbindin D9k exhibits cooperative binding of two calcium ions, hence study of the half-saturated states of the protein is critical to understanding the binding process. However, the half-saturated states are not significantly populated under equilibrium conditions. To circumvent this problem, an absolutely conserved glutamic acid residue in the C-terminal binding site (site II) has been mutated t
Background: There is a circadian and circaseptal (weekly) variation in the onset of acute coronary syndrome (ACS). The aim of this study was to elucidate whether the likelihood of ACS among emergency department (ED) chest pain patients varies with the time of presentation. Methods: All patients presenting to the Lund ED at Skåne University Hospital with chest pain or discomfort during 2006 and 20
This study prospectively examined the effects of a change of shift schedule from a fast forward-rotating schedule to a slowly backward-rotating one. The initial schedule had a forward rotation from mornings to afternoons to nights over 6 consecutive days, with 2 days on each shift followed by 4 days off before the next iteration of the cycle, whereas the new schedule had a slower backward rotation
Purpose: Soft tissue sarcomas (STS) account for less than 1% of all malignancies and constitute a heterogeneous tumor entity in which malignant fibrous histiocytomas (MFH) represent one-third and are characterized by a lack of type-specific differentiation. A defective mismatch repair (MMR) system cause the familial cancer syndrome hereditary non-polyposis colorectal cancer (HNPCC), and since occa
Today, most studies of genetic variation utilise molecular markers, making it possible to detect variation at the DNA level. This has greatly facilitated studies of genetic variation in population and evolutionary genetics, systematics and transmission genetics. By studying the inheritance of molecular markers in crosses, it is possible to map the markers, i.e. to determine their genomic positions
Background: The occupation-based intervention Balancing Everyday Life (BEL) was found effective under controlled conditions but should also be studied in a natural clinical practice context. Aim: The aim was to study the implementation process of BEL when provided in a multi-professional mental health team. The focus was particularly on how BEL was received and functioned. Methods: This qualitativ
BACKGROUND: Internalizing problems have increased among Swedish adolescents. We examined whether classroom disorder was associated with internalizing problems and whether it explained the trends in internalizing problems. Furthermore, we examined whether school contextual factors were associated with internalizing problems and whether they moderated the association between classroom disorder and i
This study follows on from a network-based assessment redesign project at a Canadian university, to investigate factors relating to academic engagement and sustained implementation. The project was designed with mini-grants, embedded support and a community of practice. Assessment facilitators worked in discipline clusters to achieve mutual goals for assessment reform targeted at authentic develo
Diffusion MRI (dMRI) has become an invaluable tool to assess the microstructural organization of brain tissue. Depending on the specific acquisition settings, the dMRI signal encodes specific properties of the underlying diffusion process. In the last two decades, several signal representations have been proposed to fit the dMRI signal and decode such properties. Most methods, however, are tested
The partition of 125I-labelled pancreatic trypsin, chymotrypsin and elastase between the inhibitors, α2-macroglobulin f and s, α1-protease inhibitor, α2-antitrypsin, inter-α-trypsin inhibitor and the specific sow colostrum protease inhibitor, was studied in vitro by gradually increasing the concentration of these proteases in blood serum from adult and newborn pigs. As revealed by immunoelectropho
BACKGROUND: Acute kidney injury (AKI) is a serious complication after major surgical procedures. We examined the incidence, risk factors, and mortality of patients who sustained AKI after abdominal surgery in a large population-based cohort.METHODS: All patients who underwent open and laparoscopic abdominal surgery (excluding genitourinary and abdominal vascular procedures), between 2007 and 2014
