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Effects of palatable diets on appetite regulation, appetite peptides and neurogenesis.

Popular Abstract in Swedish Fetma ökar epidemilikt i hela världen, delvis på grund av en ökad konsumption av dieter som innehåller mycket fett och/eller socker. Ghrelin och leptin är hormoner som produceras perifert med effekter på födointag och energihomeostas. Ghrelin i cirkulationen ökar vid energibrist, t ex vid fasta och signalerar därmed hunger. Leptin ökar vid födointag och signalerar mättnObesity is increasing throughout the world at an epidemic rate, partly due to increased consumption of diets rich in fat and/or sugar. Ghrelin and leptin are hormones, originating from the periphery, involved in the regulation of food intake and of maintaining energy homeostasis. Circulating ghrelin levels increase in times of energy deficiency, such as fasting, signalling hunger whereas circulati

HEALTH RELATED QUALITY OF LIFE AMONG PERSONS 65 YEARS OR OLDER WITH CHRONIC HEART FAILURE: AN EMPIRICAL AND METHODOLOGICAL STUDY

The aim of this thesis was to empirically and methodologically investigate health related quality of life (HRQoL) among persons 65 years or older with chronic heart failure. The design was cross-sectional and the sample was recruited from a southeast region of Sweden. The sample included 357 respondents in Paper I, II and IV and 349 respondents in Paper III. For all respondents the mean age was 79

Pooled analysis of prognostic impact of uPA and PAI-I in breast cancer patients

In this report we present an extension of the pooled analysis of the prognostic impact of urokinase-type plasminogen activator (uPA) and its inhibitor PAI-I in breast cancer patients. We analyzed a different endpoint, metastasis-free survival (MFS). We checked the consistency of the estimates for uPA and PAI-I for relapse-free survival (RFS) and MFS exploring possible sources of heterogeneity. Nod

Genetic diversity in hepatitis C virus in Egypt and possible association with hepatocellular carcinoma

Egypt has one of the world's highest prevalences of hepatitis C virus (HCV) infection, with a majority of genotype 4 infections. To explore the genetic diversity of HCV in Egypt, sera from 131 Egyptians [56 from community studies, 37 chronic hepatitis patients, 28 hepatocellular carcinoma (HCC) patients and 10 patients with non-Hodgkin's lymphoma] were genotyped by restriction fragment-length poly

Crystallography and porosity effects of CO conversion on mesoporous CeO2

Catalytic properties and thermal stability were studied for samples of mesoporous ceria with different BET specific surface area. The catalytic conversion of carbon monoxide to carbon dioxide and how thermal treatments of the catalysts influence the catalytic properties have been investigated. The materials were studied by transmission electron microscopy and by conversion profile measurements of

Development of diabetes is retarded by ACE inhibition in hypertensive patients - a subanalysis of the Captopril Prevention Project (CAPPP)

Objective The Captopril Prevention Project (CAPPP) was designed as a prospective intervention trial comparing the effect of a treatment based on the angiotensin-converting enzyme (ACE) inhibitor captopril with that of a conventional diuretic and/or beta-blocker-based therapy, in 10 985 hypertensive patients. There was no difference in the primary cardiovascular morbidity and mortality endpoint. A

Carbon cycling in subarctic tundra; seasonal variation in ecosystem partitioning based on in situ 14C pulse-labelling

Carbon assimilation and allocation were studied in a tundra ecosystem in northern Scandinavia. Seasonal variation in the below-ground carbon allocation to dissolved organic carbon (DOC), coarse-, fine-, and hair roots was investigated using in situ C-14 pulse-labelling, adding 2-3 MBq (CO2)-C-14, dm(-2) to the above-ground vegetation. Combining the allocation data with regression models of the sea

Adult Stem Cell Plasticity, Hype or Hope?

Popular Abstract in Swedish Stamceller i benmärgen reglerar balansen mellan att upprätthålla populationen av stamceller (självförnyelse) samt att producera mogna blodceller. Det finns flera studier om förmågan hos benmärgsderiverade stamceller att ge upphov till andra celltyper än blodceller, såsom hjärnceller, leverceller, muskel, hjärta, blodkärl, lungceller, tarm, hud och insulin-producerande Several studies have reported that bone marrow (BM)-derived stem cells have the capacity to give rise to cells of different type of tissue; an ability termed stem cell plasticity or transdifferentiation. Controversies exist as to how frequent this phenomenon is, or if it may be explained by alternative mechanisms. Here we have used different mouse models to study the potential plasticity of BM-der

Mg I emission lines at 12 and 18 mu m in K giants

Context. The solar mid-infrared metallic emission lines have already been observed and analyzed well, and the formation scenario of the Mg I 12 mu m lines has been known for more than a decade. Detections of stellar emission at 12 mu m have, however, been limited to Mg I in very few objects. Previous modeling attempts have been made only for Procyon and two cool evolved stars, with unsatisfactory

Assessment of aerosol optical and micro-physical features retrieved from direct and diffuse solar irradiance measurements from Skyradiometer at a high altitude station at Merak

Optical and micro-physical features of aerosol are reported using Skyradiometer (POM-01L, Prede, Japan) observations taken from a high-altitude station Merak, located in north-eastern Ladakh of the western trans-Himalayas region during January 2011 to December 2013. The observed daily mean aerosol optical depth (AOD, at 500 nm) at the site varied from 0.01 to 0.14. However, 75 % of the observed AO

Hyperbaric Oxygen Therapy as adjunctive treatment of chronic diabetic foot ulcers

Popular Abstract in Swedish Diabetes relaterade fotsår är en vanlig och allvarlig komplikation till diabetes. Orsaken till fotsår är mångfasetterad och inkluderar bland annat diabetesrelaterade nervskador och försämrad funktion i stora och små blodkärl. Vid förekomst av högt blodsocker fungerar immunförsvaret sämre och problematiska infektioner är vanligare vid diabetes. Sårläkning försämras vid lChronic diabetic foot ulcers are a source of major concern for both patients and health care systems. Oxygen deficiency plays a major role in the pathogenesis of these ulcers. Hyperbaric oxygen therapy (HBOT) has been proposed as a medical treatment for diabetic foot ulcers, but the clinical utility has not been established. Hyperbaric Oxygen in Diabetic patients with chronic Foot Ulcer (HODFU) st

Skenet som bedrog: Mai Zetterling och det svenska sextiotalet

Popular Abstract in Swedish Mai Zetterling (1925-1994) var under fyrtiotalet skådespelare, både på Dramatens scen och i populära svenska filmer. Under sextiotalet regisserade hon fyra långfilmer. Dessa filmer ? Älskande par (1964), Nattlek (1966), Flickorna (1968) och Dr. Glas (1969) ? bemöttes emellertid allt mer negativt av de svenska filmkritikerna. Under återstoden av sitt liv regisserade ZettMai Zetterling (1925-1994) was a popular actress in the 1940s. In the 1960s, she directed four feature films. The films ? Loving Couples (1964), Night Games (1966), The Girls (1968) and Dr. Glas (1969) ? were met with increasing hostility by Swedish critics, however, and after the 1960s, Mai Zetterling only directed two more feature films in her life, the British Scrubbers (1982) and the Swedish A

Digestion and Absorption of Sphingomyelin from Milk.

Popular Abstract in Swedish DIGESTION OCH ABSORPTION AV MJÖLK SFINGOMYELIN Mjölkfettet förekommer i mjölken i form av fettkulor som täcks av ett skyddande och stabiliserande hölje, bestående främst av fosfolipider och proteiner. Fettet inuti fettkulorna består huvudsakligen av triglycerider. Fosfolipider är molekyler som har både en fettlöslig och en vattenlöslig del. Därigenom kan de stabiliseraSphingomyelin (SM) is a major component of mammalian cell membranes. Due to its widespread occurrence it is a dietary component, occurring mainly in milk, eggs, meat and fish. In the cell membrane SM was earlier considered to be only a structural element, which interacts with cholesterol and forms a system for bilayer stabilization. In the last decade there has been an increasing interest in sphin

Driving forces for food packaging development in Sweden - a historical perspective

Availability of safe, edible food is essential. Food shortage has caused many wars and encouraged people to try to preserve food for a longer time, allowing storage and transport, often in some kind of package/container. The USA showed the way in developing the food sector and already prior to the 2nd World War they had self-service stores filled with packed goods. Europe, however, had to wait to

Assessment of the environmental contamination with long-lived radionuclides around an operating RBMK reactor station

The presence of man-made gamma emitting radionuclides in the region within 32 km radius of the Ignalina NPP/Lithuania has been investigated during the period 2001-2004, prior to the closure of the first 4 the two operating RBMK 1500-type reactors. Gamma spectrometric measurements of various terrestrial and aquatic plants as well as of soil samples showed moderate environmental contamination with t

Cytological variation and pathogenicity of the bumble bee parasite Nosema bombi (Microspora, Nosematidae)

In three field seasons, 2003-2005. bumble bees were collected in southern Sweden and eastern Denmark in search of microsporidian parasites. Of file 16 bumble bee species studied, microsporidia were found in Bomhus hortorum, Bomhus hypnorum, Bombas lapidarius, Bomus lucorum, Bombus pascuorum, Bombus pratorum, Bombus ruderarius, and Bombus terrestris. Only one micro-sporidian species, Nosema bombi,

The added value of PMS2 immunostaining in the diagnosis of hereditary nonpolyposis colorectal cancer.

dentification and characterization of the genetic background in patients with the hereditary nonpolyposis colorectal cancer (HNPCC) syndrome is important since control programmes can in a cost-effective manner prevent cancer development in high-risk individuals. HNPCC is caused by germline mismatch repair (MMR) gene mutations and the genetic analysis of HNPCC therefore includes assessment of micro

Atrophy and neoplastic transformation of the ileal pouch mucosa in patients with ulcerative colitis and primary sclerosing cholangitis - A case control study

INTRODUCTION: Patients with ulcerative colitis and primary sclerosing cholangitis have an increased risk of developing carcinoma both in the bile ducts and in the colon. PURPOSE: To investigate whether this patient group also has an increased risk of developing atrophy and neoplasia in the deal pouch mucosa after construction of a pelvic pouch with an ileoanal anastomosis or a continent Kock ileos