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We present a novel, global 30 arc seconds (∼1 km at the equator) population projection dataset covering each year from 2010 to 2100 that is consistent with both country level population and gridded urban fractions from the Coupled Model Intercomparison Project 6 (CMIP6). While IPCC population projections until 2100 are available at country level for Socio-Economic Pathways (SSPs), land cover (incl
p53 is a transcription factor that participates in cell cycle checkpoint processes and apoptosis. The protein product of the murine double minute gene 2 (mdm-2) plays a central role in the regulation of p53. In response to DNA-damaging agents, the wild-type p53-activated fragment 1 (WAF1 also known as p21) is an important downstream effector in the p53-specific growth arrest pathway. In breast can
The retail sector is facing fundamental transformations in nearly every part of the value chain, affecting the need for competence development in many retail professions. As most learning at work is informal and there is a deficit of studies of how such learning takes place in specific professions, systematized work with competence development is hampered. We therefore investigated the informal le
Background: Magnetization transfer (MT) saturation reflects the additional saturation of the MRI signal imposed by an MT pulse and is largely driven by the saturation of the bound pool. This reduction of the bound polarization by the MT pulse is less efficient than predicted by the differential B1-square law of absorption. Thus, B1 inhomogeneities lead to a residual bias in the MT saturation maps
Brain tissue segmentation plays a crucial role in feature extraction, volumetric quantification, and morphometric analysis of brain scans. For the assessment of brain structure and integrity, CT is a non-invasive, cheaper, faster, and more widely available modality than MRI. However, the clinical application of CT is mostly limited to the visual assessment of brain integrity and exclusion of copat
Background: The air traffic management (ATM) system has historicallycoped with a global increase in traffic demand ultimately leading toincreased operational complexity.When dealing with the impact of this increasing complexity on systemsafety it is crucial to automatically analyse the losses of separation(LoSs) using tools able to extract meaningful and actionableinformation from safety reports.C
With the help of modern technologies and advances in communication systems, the functionality of Industrial control systems (ICS) has been enhanced leading toward to have more efficient and smarter ICS. However, this makes these systems more and more connected and part of a networked system. This can provide an entry point for attackers to infiltrate the system and cause damage with potentially ca
BACKGROUND: Patients presenting with peritoneal metastases (PM) of colorectal cancer (CRC) can be curatively treated with cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC). Angiogenesis is under control of multiple molecules of which HIF1a, SDF1, CXCR4, and VEGF are key players. We investigated these angiogenesis-related markers and their prognostic value in patient
Doktorsavhandling i Gamla testamentets exegetik. I avhandlingen kartläggs vilka tolkningsstrategier som är tongivande i modern kommentarlitteratur av Psaltarens s.k. 'förbannelsepsalmer,' dvs. bibeltexter som vanligen utelämnas i modernt gudstjänstliv av innehållsliga skäl då de uttrycker den bedjandes önskan om hämnd och/eller våld gentemot fiender. En översikt av den exegetiska diskursen, så somDue to their calls for vengeance and violence the so called imprecatory psalms are generally considered ethically difficult and subsequently omitted from liturgy. This becomes particularly evident in breviaries, such as the Roman Catholic Church’s Liturgy of the Hours, where both entire psalms and individual verses have been omitted. The widespread omission of lament psalms (including imprecatory
International collaboration is clearly a key priority in higher education andresearch (HER) policy and practice. The competition for students and excellentresearch and teaching staff is now a global one and this is reflected inthe increasing salience of phenomena such as the Shanghai and Times HigherEducation Rankings for monitoring the performance of HER institutions. Thischapter takes its point
Background: Peripheral arterial disease (PAD) is a common atherosclerotic disease with severity ranging from asymptomatic to chronic limb threatening ischemia. The aim of the present cross-sectional study was to identify novel biomarkers associated with PAD. Patients and methods: Levels of 91 cardiovascular specific proteins in plasma samples were measured by the Proseek Multiplex CVD III96x96 pa
Questions concerning children’s place in a worshipping community keeps reemerging in the Church of Sweden, as well as in other churches. Often ideals of inclusivity and children’s participation collide with ideals of a solemn, calm and “adult” liturgy. Children might simultaneously be seen as carriers of hope and a special proximity to God and as disturbers: they make noise and are “too young to uQuestions concerning children’s place in a worshipping community keeps reemerging in the Church of Sweden, as well as in other churches. Often ideals of inclusivity and children’s participation collide with ideals of a solemn, calm and “adult” liturgy. Children might simultaneously be seen as carriers of hope and a special proximity to God and as disturbers: they make noise and are “too young to u
Imaging large areas of a sample non-destructively and with high resolution is of great interest for both science and industry. For scanning coherent X-ray diffraction microscopy, i. e., ptychography, the achievable scan area at a given spatial resolution is limited by the coherent photon flux of modern X-ray sources. Multibeam X-ray ptychography can improve the scanning speed by scanning the sampl
Bacterial adhesion to the host is the most decisive step in infections. Trimeric autotransporter adhesins (TAA) are important pathogenicity factors of Gram-negative bacteria. The prototypic TAA Bartonella adhesin A (BadA) from human-pathogenic Bartonella henselae mediates bacterial adherence to endothelial cells (ECs) and extracellular matrix proteins. Here, we determined the interaction between B
PURPOSE: To investigate factors related to omitted total body skin examination (TBSE) in skin cancer diagnostics while managing patients using teledermoscopy (TDS) in Swedish primary care.METHODS: 4,987 TDS referrals from primary care centers were analyzed to identify factors associated with failing to perform TBSE. Data collected included age, gender of patient and physician, and reason for a vis
Concerns about fairness among countries remain significant obstacles to a stronger global climate treaty. This paper addresses the distributional implications of two mechanisms to strengthen the Paris Agreement, the incorporation of national carbon pricing, and the tightening of nationally determined contributions (NDCs). Both are found to be viable mechanisms. They are also less extreme, and ther
In recent years, global technology-based competition has not only intensified, but become increasingly linked to a more comprehensive type of competition between different political and value systems. The globalist assumptions of the post-Cold War era that reliable mutually beneficial agreements could be reached with all nations, regardless of ideology, have been shattered. A previously less visib
