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Reliable and cost-effective operation of structural systems over their service life depends on the implementation of Structural Health Monitoring (SHM) and maintenance activities, which influence operational costs, the expected costs of failure and downtime. Decision Value Analysis (DVA) provides a framework to quantify the value of such activities by evaluating their effect on total expected life
Nickel-based catalysts are the most promising alternative to replace platinum in hydrogen conversion devices in alkaline media. One approach to narrowing the performance gap between Pt and Ni is to fine-tune the nickel surface coverage by (hydr) oxide (NiOxHy) species, which determines its electrocatalytic activity for the hydrogen oxidation (HOR) and hydrogen evolution (HER) reactions. As Ni easi
Effective medical education relies on clearly defined learning objectives that foster deep and meaningful learning. This article presents a consensus-driven proposal for national learning objectives in dermatology and venereology within Sweden’s new medical programme qualifying for licensure. The primary aim is to harmonize educational standards across all medical faculties and to establish a comm
INTRODUCTION: Automated cerebrospinal fluid (CSF) biomarker assays have largely replaced manual immunoassays for measuring amyloid pathology in CSF. We refitted and validated the ABIDE model, predicting progression from mild cognitive impairment (MCI) to dementia, with CSF measurements from the automated Elecsys platform. METHODS: We included 2413 MCI participants (998 [41%] amyloid-positive) from
Take Home Message Using Germany as a case example, a comparison between organized mammography screening and contemporary, risk-adapted screening for prostate cancer suggests that prostate-specific antigen–based early detection with incorporation of magnetic resonance imaging and active surveillance can achieve benefits comparable to those of mammography while addressing previous concerns about ove
Background:Trauma patients present with heterogeneous injury patterns that are challenging to represent in statistical models. Traditional approaches either use high-dimensional one-hot encoding, resulting in sparse features, or aggregate injuries into summary scores that lose patient-specific detail.Objective:This study developed data-driven ICD-10 embeddings for trauma injuries and evaluated the
The increasing prevalence of antimicrobial-resistant bacterial infections has ushered in a major global public health crisis. Judicious or restricted antimicrobial use in animal agriculture, aiming to confine the use for the treatment of infections, is the most commonly proposed solution to reduce selection pressure for resistant bacterial strains and resistance genes. However, a multifaceted solu
The large MIMIC waveform dataset, sourced from intensive care units, has been used extensively for the development of Photoplethysmography (PPG) based blood pressure (BP) estimation algorithms. Yet, because the data comes from patients in severe conditions-often under the effect of drugs-it is regularly noted that the relationship between BP and PPG signal characteristics may be anomalous, a claim
Population ageing is a fact of all advanced economies. Fewer people are born all the while current members live longer. The support which old people have come to depend on, for example through elderly care and pensions, thus becomes increasingly expensive. This accentuates an assurance problem. Although it has been and still is the case that the young are willing to support the currently old, this
The ATLAS physics program at the High Luminosity LHC (HL-LHC) calls for a precision in the luminosity measurement of ±1%. A larger uncertainty would represent the dominant systematic error in some precision measurements, including the Higgs sector. To fulfil such requirement in an environment characterized by up to 140 simultaneous interactions per bunch crossing (200 in the ultimate scenario), AT
Men who sell sex to other men are still an under-researched area of study, despite their long presence in our history. But those who are selling sex in the 21st Century have new and peculiar characteristics. This paper highlights the presence of the so-called middle-class, men with high educational credentials that have decided to engage in sex working. Moreover, indulging in the encounter itself
Laboratory x-ray micro- and nano-tomography are emerging techniques in biomedical research. Through the use of phase-contrast, sufficient contrast can be achieved in soft tissue to support medical studies. With ongoing developments of x-ray sources and detectors, biomedical studies can increasingly be performed at the laboratory and do not necessary require synchrotron radiation. Particularly nano
Palliative care clinicians provide psychological support throughout their patients' journeys with illness. Throughout our series exploring the psychological elements of palliative care (PEPC), we suggested that the quality of care is enhanced when clinicians have a deeper understanding of patients' psychological experience of serious illness. Palliative care clinicians are uniquely poised to offer
Denmark has long been known as a pioneer in renewable energy technology development. Apart from technological leadership, Denmark has also been the home to many community-based renewable energy initiatives. Citizen involvement in local energy projects has been key to increasing and maintaining acceptance to wind, solar and biomass. Three Danish islands (Bornholm, Samsø and Ærø) have been particula
Long-term follow-up data from trials of digital mental health interventions are rare. This study reports 2-year follow-up data from a non-inferiority trial (N = 152) comparing stepped-care (internet-delivered cognitive behavioral therapy [CBT] followed by traditional in-person CBT if needed) vs in-person CBT for pediatric obsessive-compulsive disorder. Both treatment groups had comparable long-ter
This thesis addresses the theoretical treatment of photoelectrons in attosecond and free-electron laser sciences. Wehave implemented methods that extract information on the photoionization process, which we use to investigateinterferometric schemes with particular focus on multiphoton ionization and strong-field effects in attosecondmetrology and coherent control of photoelectrons in free-electron
