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While the major drivers of melanoma initiation, including activation of NRAS/BRAF and loss of PTEN or CDKN2A, have been identified, the role of key transcription factors that impose altered transcriptional states in response to deregulated signaling is not well understood. The POU domain transcription factor BRN2 is a key regulator of melanoma invasion, yet its role in melanoma initiation remains
The identification of a permanent establishment is the principle used by the Member States of the European Union to determine whether a company is subject to the tax jurisdiction of a State. In the digital context, the notion of permanent establishment is often questioned by States, as companies can provide services remotely without having any physical presence in the territory of a State. This th
LU Holding AB 556500-1467 Box 117, SE - 221 00 Lund, Sweden, Visiting address The Spark, Medicon village, Scheeletorget 1, Lund Telephone +46 46-222 00 00 Internet www.innovation.lu.se 1 A" rsredovisning för LU Holding AB 556500-1467 Räkenskapsåret 2023-01-01 – 2023-12-31 Transaktion 09222115557517147306 Signerat CW, KE, JA, HP, CE, UR, RM, EU, ME LU Holding AB 556500-1467 Box 117, SE - 221 00
A dinuclear manganese complex {[(Mn2L)-L-II,IIII(mu-OAc)(2)]-ClO4} has been synthesised, where L is the dianion of 2-{[bis-(pyrid-2-ylmethyl)amino]methyl}-6-{[(3,5-di-tert-butyl-2- hydroxybenzyl)(pyrid-2-ylmethyl)amino]methyl)-4-methylphenol, an unsymmetric binucleating ligand with two coordinating phenol groups. The two manganese ions, with a Mn-Mn distance of 3.498 angstrom, are bridged by the t
There is an urgent need for improved respiratory surveillance of preterm infants. Gas in scattering media absorption spectroscopy (GASMAS) is emerging as a potential clinical cutaneous monitoring tool of lung functions in neonates. A challenge in the clinical translation of GASMAS is to obtain sufficiently high signal-to-noise ratios in the measurements, since the light attenuation is high in huma
For model-based quantitative reconstructions of past vegetation cover on the scale of landscapes, pollen productivity estimates (PPEs) are key input parameters. In this study, we employed a random sampling strategy to collect moss polsters at 20 sites in Changbai Mountain, northeastern China. A detailed vegetation survey within 1000-m radius around each sampling point was carried out and digitized
Bacteria and humans have co-evolved since their common existence. They have thereby developed very specific defence and target mechanisms against one another. Understanding the complex biomolecular processes behind these interactions can be of great use for developing treatments against bacterial diseases. The aim of this thesis project was to verify, and introduce a model for understanding, the i
Many studies have over the years utilized gravity models derived from trade theories to investigate how various factors affect trade in agricultural goods. Although technological improvements could be considered in such models, few studies have considered this topic in depth, leaving a void to fill. To partly fill this void, this study has chosen the silk sector to analyze the impact of technologi
This study provides information about the concentration of Tungsten (W), Hafnium (Hf) and Tantal (Ta) in the ESS soil and recommendations on the most appropriate sample preparation and measurement technique to assess contamination by these elements. The current levels of W, Hf and Ta measured in this study are in agreement with the estimated values from previous geological surveys. ICP MS showed l
On-Going Change in English Modality: Emancipation Through Frequency The English modal expressions BE going to, HAVE got to, and want to are often contracted to gonna, gotta, and wanna in spoken language. These contracted forms have gained both in frequency and conventionality in recent times.In this article, I present an investigation into the status of the contractions between phonetic reduction
One of the leading challenges presented in 21st century for packaging industry is to address the growing environmental problems related to non-renewable flexible packaging. This leads to new growing interest in bio-based materials, among them cellulose nanocrystals (CNCs), which have already shown good performance in improving anti-fog and oxygen & water vapor barrier properties when applied t
MILJÖVETENSKAP Preliminärt schema datum 2018-12-10 Kurs: MVEB15 Miljöpolitik och förvaltning Kursansvarig: Åsa Knaggård Lärare: Elias Isaksson (EI), Åsa Knaggård (ÅK), Tobias Nielsen (TN), Maja Tejre (MT) Lokaler: Raggmossan, Ekologihuset Litteratur: Carter, Neil (2018). The politics of the environment. Ideas, activism, policy . Tredje upplagan. Cambridge: Cambridge University Press. Dahlström, Ca
https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/schema_mveb15_vt2019_v5.pdf - 2026-07-23
