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Currency Hedging Management in Global Firms. The case of Heidelberg Cement

Our ever-changing world has to a great extent created a need of efficient financial risk-management programs for financial institutions and corporations operating in a demanding international environment. These changes have however also increased the types of financial tools and derivatives used to handle the multifold macroeconomic exposures. Companies have therefore diversified opportunities to

Geospatial data integration and visualisation using Linked Data

Geospatial data are increasingly available nowadays, and this leads to more analyses and visualisation of geospatial data from several sources. To enable this, we need homogenous data as well as proper integration methods. Geospatial data integration has been a longstanding research topic for decades, and this paper discusses the utilisation of Linked Data technology stack to alleviate the geospat

Stability and Local Unfolding of SOD1 in the Presence of Protein Crowders

Using NMR and Monte Carlo (MC) methods, we investigate the stability and dynamics of superoxide dismutase 1 (SOD1) in homogeneous crowding environments, where either bovine pancreatic trypsin inhibitor (BPTI) or the B1 domain of streptococcal protein G (PGB1) serves as a crowding agent. By NMR, we show that both crowders, and especially BPTI, cause a drastic loss in the overall stability of SOD1 i

Spatially and functionally distinct subclasses of breast cancer-associated fibroblasts revealed by single cell RNA sequencing

Cancer-associated fibroblasts (CAFs) are a major constituent of the tumor microenvironment, although their origin and roles in shaping disease initiation, progression and treatment response remain unclear due to significant heterogeneity. Here, following a negative selection strategy combined with single-cell RNA sequencing of 768 transcriptomes of mesenchymal cells from a genetically engineered m

Five-year changes in dietary intake and body composition in adolescents with severe obesity undergoing laparoscopic Roux-en-Y gastric bypass surgery

Background: Information is scarce on long-term changes in energy intake (EI), dietary energy density (DED), and body composition in adolescents undergoing laparoscopic Roux-en-Y gastric bypass (RYGB). Objectives: To investigate long-term changes in EI, DED, and body composition in adolescents after LRYGB. Setting: University hospitals, multicenter study, Sweden. Methods: Eighty-five adolescents (6

Can enzymatic stoichiometry be used to determine growth-limiting nutrients for microorganisms? - A critical assessment in two subtropical soils

The measurement of potential enzymatic activities has been proposed as an efficient method to infer nutrient limitations for microorganisms in environmental samples. To validate this use, confirmation with direct methods of microbial growth responses to resource additions are required. We experimentally manipulated nutrient-poor soils from the afromontane subtropics with relatively low (grassland

Using radio telemetry to study dispersal of the beetle Osmoderma eremita, an inhabitant of tree hollows

This paper describes a radio-tracking study of Osmoderma eremita, a large Scarabaeid beetle, living in hollow trees. The study seems to be the first in which radio telemetry has been used with a flying insect in the field. Some 74 adult beetles were tagged with radio transmitters weighing 0.48-0.52 1, and having a nominal battery life of 12-20 days. Transmissions were detected at ranges of up to 3

Education for Sustainable Development and the Young Masters Program

Education is the foundation for achieving sustainable development. The United Nations Decade of Education for Sustainable Development declared from January 2005 to December 2014 demands a concerted effort to expand environmental education around the world. The Young Masters Program is an international education course, which utilises the internet to connect students, teachers, and tutors in differ

A Charter Moment: Restructuring Governance for Sustainability

We are living in a highly dynamic, human-dominated Earth System in which non-linear, abrupt and irreversible changes are not only possible but also probable. These changes require institutional structures capable of steering human society away from critical tipping points and irreversible change and ensuring sustainable livelihoods for all. We see 2012 as a charter moment, a historic opportunity t

Co-Exploring Everyday Life of Adults with ADHD

There are relatively few studies based on an individual adult perspective on ADHD which takes into account how various factors interact and affect everyday life. Compensatory strategies can facilitate life for people with ADHD and those strategies might include the use of assistive technology or cognitive support. The purpose of this paper is to present and discuss how various factors can facilita