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The unification of quantum mechanics and general relativity has long been elusive. Only recently have empirical predictions of various possible theories of quantum gravity been put to test, where a clear signal of quantum properties of gravity is still missing. The dawn of multi-messenger high-energy astrophysics has been tremendously beneficial, as it allows us to study particles with much higher
BACKGROUND: So far, the ImmuKnow Immune Cell Function Assay (Cylex, Inc., Columbia, MD, USA) has been used to assess risks of infection and rejection in transplant patients. We hypothesized that the ImmuKnow assay might be used for mortality screening in transplant patients overall.METHODS: In the period of February 2007 to December 2009, at the Uppsala University Hospital, 362 patients who receiv
Climate change calls for adaptive strategies to manage land system across governance levels, as differing multi-level policies distinctly shape land system and long-term ecosystem resilience. This study proposes an iterative approach for optimizing land-use pathways that balance competing policy objectives across national, provincial, and local levels without compromising ecosystem integrity in a
Mantle cell lymphoma (MCL) is a relatively rare B-cell lymphoma subtype, with a higher incidence among males and a median age of 70 years at diagnosis. MCL is characterized by clinically diverse behavior, from indolent disease to extremely aggressive, related to the presence of biological risk factors such as proliferation rate and TP53 mutations. Most often, patients present with disseminated dis
IntroductionWater scarcity is a growing problem, with estimates showing that 40% of the world’s population could face water shortages by 2030. This issue is even worse because only 3% of the Earth’s water is freshwater, while 97% is seawater. Finding better ways to save and use water is critical to solving this problem. At the same time, renewable energy is essential for reducing carbon emissions
The dissertation Deductionis coloniarum rationes & causae, submitted at Uppsala University in 1668 under the presidency of Johannes Schefferus, appears to be the firstcontribution to the Swedish discourse on the subject of colonisation and colonialism. In this paper, a translation of the text is presented with a commentary and a list of sources. In an introduction to the translation, which dis
A central challenge in linguistics pertains to understanding how the polished, static form of a written text emerges from the messy, moment-by-moment decisions of the writer. While the structures of finished texts have been extensively theorized, and the real-time cognitive processes of writing have been widely studied, the relationship between these real-time processes and the functional linguist
A novel family of symmetric squaramide-based LMWGs has been synthesised, functionalized with both dansyl moieties and alkyl chain spacers of different lengths (n = 3 and n = 4 named L1 and L2, respectively). L1 and L2 are able to form hydrogels in the DMSO : H2O mixture in different ratios and concentrations. The gels obtained were characterized by means of rheology, TEM and small angle X-ray scat
Considering the distinct etiological pathways and molecular characteristics of different lung cancer subtypes, it is crucial to develop subtype-specific prevention strategies and therapeutic targets. This study aimed to identify protein biomarkers and potential therapeutic targets for specific subtypes of lung cancer by integrating population-based observational studies and Mendelian randomisation
Chants for Crown Prince Reza Pahlavi during Iran’s nationwide protests are not expressions of nostalgia but demands for political legitimacy and continuity. As Iran’s opposition remains fragmented and burdened by past violence, many Iranians increasingly look to institutional legitimacy rather than ideology. The article argues that legitimacy will be the decisive factor shaping Iran’s potential tr
What is the role of deictic gestures in expressing affective valence, and can such gestures serve as an indicator of awareness in choice making? To examine this, we analyzed participants’ deictic gestures toward preferred and non-preferred picture alternatives in an experimental choice justification task. The task involved manipulation: in some trials, participants were presented with the rejected
The special degeneracy which occurs in the harmonic-oscillator potential when two of the frequencies have ratios of small integer numbers is exploited. Favored shell energies occur for particle numbers which vary with the third frequency. Applications to realistic nuclear potentials show that this degeneracy leads to special shell effects for axial shapes (1:1 ratio) but also for the 2:1 ratio exe
Integrated Continuous Biomanufacturing reduces manufacturing costs while maintaining product quality. A key contributor to high biopharmaceutical costs, specifically monoclonal antibodies (mAbs), is chromatography. Protein A ligands are usually preferred but still expensive in the manufacturing context, and batch chromatography under-utilizes the columns' capacity, compromising productivity to mai
We provide the theoretical foundation for the recent tests of equal forecast accuracy and encompassing by Pitarakis (2023) and Pitarakis (2025), when the competing forecast specification is that of a factor-augmented regression model. This should be of interest to practitioners, as there is no theory justifying the use of these simple and powerful tests in such a context. In pursuit of this, we em
The aim of this study was to describe prerequisites for online collaboration for user participation in co-design of online digital services as perceived by people with impairments and to develop requirements for how online collaboration should be designed to be accessible for all participants. An exploratory study was conducted in parallel to activities in two co-design projects. Researchers, acce
In today’s volatile and changing environment employment, innovation, and economic growth are basic characteristics of small and medium enterprises (SMEs). The Analytical Hierarchy Process (AHP) is used to investigate the challenges and enablers of digitalization in SMEs. Expert responses provide numerical weights to 6 barriers and 5 alternatives using Super Decisions v3.2 software. The results sho
Background: Tau-Positron Emission Tomography (PET) has become central in Alzheimer’s disease (AD) research and clinical settings. Multiple preprocessing pipelines for tau-PET quantification have been described, with satisfactory performance but direct comparisons remain scarse. Our study evaluates the comparability of two commonly used PET preprocessing methods, respectively in native and standard
