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Background: With a yearly incidence of 56 per 100,000 inhabitants, colorectal cancer (CRC) is one of the most common malignancies in the Western world, representing the third leading cause of cancer-related mortality. Within three years after the diagnosis of CRC, 29% of patients will have developed liver metastases. Liver resection is a possibly curative treatment, and several preoperative strate

PURPOSE: The feasibility of hyperpolarized 129Xe for fast MR angiography (MRA) was evaluated using the echo-planar imaging (EPI) technique.MATERIAL AND METHODS: Hyperpolarized Xe gas was dissolved in ethanol, a carrier agent with high solubility for Xe (Ostwald solubility coefficient 2.5) and long relaxation times. The dissolved Xe was injected as a bolus into a flow phantom where the mean flow ve

The measurement of absorbed dose distributions using dosemeter gel and magnetic resonance imaging (MRI) in a standard geometry has been investigated. Absorbed depth-dose curves and profiles measured with this new technique show good agreement with corresponding measurements using diodes. This was proven in a 60Co beam as well as an electron beam. The dosemeter gel is made of agarose and ferrous su

An efficient numerical method for nearly simultaneous computation of all conditional moments needed for quasi maximum likelihood estimation of parameters in discretely observed stochastic differential equations is presented. The method is not restricted to any particular dynamics of the stochastic differential equation and is virtually insensitive to the sampling interval. The key contribution is

We study System Optimum Dynamic Traffic Assignment (SO-DTA) for realistic traffic dynamics controlled by variable speed limits, ramp metering, and routing controls. We consider continuous-time cell-based Dynamic Network Loading models that include as special cases the Cell Transmission Model (CTM) with FIFO rule at the diverge junctions as well as non-FIFO diverge rules. While a straightforward co

Massive multiple input multiple output (MIMO) is a revolutionary communication technique, where large numbers of antennas are employed at the base stations to increase the spectral efficiency, reliability and data rate of the system. Moreover, in multi-user MIMO (MU-MIMO) multiple users can be served by the base stations on the same time-frequency resource. Distributed antenna system (DAS) is a fo

PalCom is a pervasive middleware that can be used to assemble services provided by networked devices into configurations, called assemblies, for specific use cases by the user. In this dissertation, we present the development of a networking media abstraction framework for PalCom that abstracts different network interfaces in a PalCom device to upper layers of PalCom. The media abstraction framewo

Breast cancer is the most common cancer among women worldwide, although the mortality rates have decreased in the last decades. Breast cancer is a heterogeneous disease, and treatment resistance is a significant clinical problem in spite of the overall high survival rates. Improved screening programs, novel surgical techniques, and adjuvant treatments have contributed to the improved survival,

Are capitalists more likely than others to justify ‘immoral’ acts such as bribery ortax evasion? This chapter investigates the conditions under which this is the case.While qualitative studies continue to document the nuances, mechanisms, andpractices of cheating and fraud among capitalists, quantitative work that tests the presence of fraud in modern economic life across a wide range of societies

Thin ion transmission detectors can be used as a part of a telescope detector for mass and energy identification but also as a pre-cell detector in a microbeam system for studies of biological effects from single ion hits on individual living cells. We investigated a structure of graphene on silicon carbide (SiC) with the purpose to explore a thin transmission detector with a very low noise level

Monitoring vegetation gross primary production (GPP) is required for both carbon balance studies and early warning systems aiming to detect unfavorable crop and pasture conditions. This manuscript describes the assimilation of MODIS observations by a simple process model, fed by meteorological data (temperature, incident radiation and rainfall) and linked with a canopy reflectance model, to estima

Environmental research infrastructures (RIs) support their respective research communities by integrating large-scale sensor/observation networks with data curation services, analytical tools and common operational policies. These RIs are developed as pillars of intra-and interdisciplinary research, however comprehension of the complex, pathologically interconnected aspects of the Earth's ecosyste

A promising approach for addressing sustainability problems is to recognize the unique conditions of a particular place, such as problem features and solution capabilities, and adopt and adapt solutions developed at other places around the world. Therefore, research and teaching in international networks becomes critical, as it allows for accelerating learning by sharing problem understandings, su

Drawing from several years of field work and about 30 life story interviews,this chapter presents a case of contemporary evangelical mobility that cannotbe squarely placed within any of the related academic debates about ‘(religious)tourism’, ‘pilgrimage’, ‘short-term missions’, ‘international volunteering’ or ‘migration’ simply because it is intrinsically related to all these phenomena at the sam

Conditional random fields were trained to detect marker words for negation and speculation in two corpora belonging to two very different domains: clinical text and consumer review text. For the corpus of clinical text, marker words for speculation and negation were detected with results in line with previously reported interannotator agreement scores. This was also the case for speculation marker

We prospectively investigated anti-Müllerian hormone (AMH) as a measure of ovarian insult in young females during and after treatment for Wilms tumor (WT), osteosarcoma (OS), and Ewing sarcoma (ES). Twenty-one female childhood cancer patients, with a mean age of 7.9 years (range 0.6-17), entered the study. Levels of AMH, follicle-stimulating hormone (FSH), and luteinizing hormone were monitored at

Aims: Bacterial infection is a major challenge in wound care. Antimicrobial wound dressings are of great value for treating wound infections. Endolysins are evolving as a new class of antimicrobials with multiple applications. This study describes the production and evaluation of T4 lysozyme (T4Lyz), product of gene e of the T4 bacteriophage, fused with Cellulose Binding Module (CBM) for facile im

In this paper, we cast the idea of antithetic sampling, widely used in standard Monte Carlo simulation, into the framework of sequential Monte Carlo methods. We propose a version of the standard auxiliary particle filter where the particles are mutated blockwise in such a way that all particles within each block are, first, offspring of a common ancestor and, second, negatively correlated conditio