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The biological functions of proteins depend on their physical interactions with other molecules, such as proteins and peptides. Therefore, modeling the protein-ligand interactions is important for understanding protein functions in different biological processes. We have focused on the cleavage specificities of HIV-1 protease, HCV NS3 protease and caspases on short oligopeptides or in native prote

Abstract is not available

As new therapeutic areas in which genetic material is employed, i.e. gene therapy and DNA vaccination, are expanding, a substantial increase in the demand for gene vectors, e.g. plasmid DNA, is foreseen. Chromatography, being a high-resolution method, is considered essential for the purification of gene vectors when high purity is required. Plasmids are large molecules, which cannot penetrate the

Governmental organisations are becoming more critically dependant on IT systems such as communication systems or patient data systems, both for their everyday tasks and their role in crisis relief activities. Therefore it is important for the organisation to analyse the reliability of these systems as part of the organisation’s risk and vulnerability analysis process. This paper presents a practic

Vehicle rollover accidents are a particularly dangerous form of road accident. Commercial vehicles are especially prone to rollover accidents due to their high centres of gravity. A nonlinear control strategy is presented which guarantees asymptotic tracking of a yaw rate reference while bounding the roll angle, thus preventing rollover. A new computationally-efficient control allocation strategy

Antenna matching is improved with adaptive 0.35 μm CMOS circuits based on switched shunt capacitors arranged in capacitor banks and external series inductors. The simulated circuits are optimized for the ISM 2.4 GHz band. The circuits provide a VSWR ⩽ 2 match for every impedance with VSWR ⩽ 5. There is a 1 dB power loss for a perfect 50 Ω → 50 Ω transformation, a break-even point at VSWR = 1.5, an

Detta är en ministudie över den körsång som bedrivits inom Lunds kyrkliga samfällighet under 2012 med fokus på vuxna körsångare, deras musikaliska bakgrund och relation till musik, i synnerhet körsång. Sångarnas profil kompletteras med kommentarer av några körledare och av författaren i egenskap som musikhistoriker.

This book comprehensively accounts the advances in data-based approaches for hydrologic modeling and forecasting. Eight major and most popular approaches are selected, with a chapter for each stochastic methods, parameter estimation techniques, scaling and fractal methods, remote sensing, artificial neural networks, evolutionary computing, wavelets, and nonlinear dynamics and chaos methods.These a

Speculations about the future of the Scandinavian standard languages concerning the degree of standardization and in relation to the expanding use of Anglo-American for various purposes. Also the prospects of Swedish in Finland and Neo-Norwegian in Norway are discussed.

Two-phase flows are commonly found incomponents in energy systems such as evaporators and boilers. Theperformance of these components depends among others on thecontroller. Transient models describing the evaporation process areimportant tools for determining control parameters, and fast loworder models are needed for this purpose. This article describes ageneral moving boundary (MB) model for mod