Targeting the androgen receptor (AR) pathway prolongs survival in patients with prostate cancer, but resistance rapidly develops. Understanding this resistance is confounded by a lack of noninvasive means to assess AR activity in vivo. We report intracellular accumulation of a secreted antigen-targeted antibody (SATA) that can be used to characterize disease, guide therapy, and monitor response. A

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Uppsatsen behandlar Supersnippan som en del av en bredare feministisk rörelse och ämnar besvara hur denna Facebooksida fungerar som en parallell diskursiv arena, vilka strategier som används för att sprida ett feministiskt budskap, samt vilka hinder och möjligheter som Facebook erbjuder i förhållande till medielandskapet och dess politiska ekonomiska struktur. Studien är utförd med en fallstudieme

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The dendritic cell (DC) lineage encompasses a diverse population of cells with unique subtype-specific functions. In peripheral blood, four DC subsets have been identified based on their distinct expression of CD1c, CD141, CD16, and CD123, and these subpopulations exhibit functional properties in immune responses. However, their respective roles in allergic diseases, such as rhinitis, are unclear.

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