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Does sertraline provide symptomatic relief for chronic breathlessness in people with advanced disease whose underlying cause(s) are optimally treated?223 participants with chronic breathlessness (modified Medical Research Council breathlessness scale ≥2) who had optimal treatment of underlying cause(s) were randomised 1:1 to sertraline 25-100 mg (titrated upwards over 9 days) or placebo for 4 week
In this cumulative incidence study of the entire population of Sweden, we examined the association between neighbourhood income level and injury risks across a comprehensive set of individual variables. The population, stratified by age (0-14, 15-64, and > or =65 years), was followed for incident injury events in 1998. Multilevel logistic regression was used to examine the associations between nei
Background: There is an ongoing discussion on whether routinely patch testing with p-phenylenediamine (PPD) 1.0% pet. is safe, owing to the risk of patch test sensitization. Late-appearing patch test reactions may reflect patch test sensitization, but may also be attributable to a low degree of pre-existing sensitization. Objectives: To follow the positive patch test reactions to PPD and its salt
The aim is to investigate associations between sexual orientation and experience of suicide thoughts and suicide attempts. The 2012 public health survey in Scania, southern Sweden, is a cross-sectional population-based study including 28,029 participants aged 18–80 with 51.7% participation. The associations between sexual orientation and experience of suicide thoughts and attempts were investigate
Aim: Acute otitis media (AOM) is a common childhood disease, which often becomes recurrent (rAOM). A small reduction of AOM episodes has been noted in unselected child cohorts after vaccination with heptavalent conjugate pneumococcal vaccine (PCV7). The purpose of this study was to investigate how vaccination affects young children at risk of developing rAOM. Methods: Ninety-six children with an A
Endometrial stromal sarcomas (ESS) are rare malignancies, accounting for less than 10% of uterine sarcomas. Apart from the chromosomal rearrangement t(7;17)(p15;q21), which leads to the JAZF1/SUZ12 chimera, cytogenetic studies have shown that the chromosome band 6p21 is often rearranged in ESS. The translocation partners involved in the 6p21 rearrangements differ among the tumors, but chromosome 7
Water-, sanitation-, and hygiene-related diseases are killing many people each year in developing countries, including Rwanda, and children under the age of five are the most vulnerable. This research assessed human waste disposal practices, knowledge on diseases caused by contact with human faeces, and knowledge on causes and prevention of selected WASH-related diseases. One thousand one hundred
Background and purpose. Sensorimotor stroke (SMS) is often included among the lacunar syndromes, although the underlying cause of this stroke-subtype is less well documented. To this end we analysed 32 patients presenting with a sensorimotor syndrome. Methods. The study protocol included vascular risk factors, echocardiography, Doppler sonography of carotid arteries, CT scan and MRI of the brain.
X-ray free-electron lasers (FELs), which amplify light emitted by a relativistic electron beam, are extending nonlinear optical techniques to shorter wavelengths, adding element specificity by exciting and probing electronic transitions from core levels. These techniques would benefit tremendously from having a stable FEL source, generating spectrally pure and wavelength-tunable pulses. We show th
We present a detailed experimental and numerical study of the structural and dynamical properties of salt-free lysozyme solutions. In particular, by combining small-angle X-ray scattering (SAXS) data with neutron spin echo (NSE) and rheology experiments, we are able to identify that an arrest transition takes place at intermediate densities, driven by the slowing down of the cluster motion. Using
Influences on stratospheric aerosol during the first four months following the eruption of Kasatochi volcano (Alaska) were studied using observations at 10700 +/- 600 m altitude from the CARIBIC platform. Collected aerosol samples were analyzed for elemental constituents. Particle number concentrations were recorded in three size intervals together with ozone mixing ratios and slant column densiti
Real-time 3D reconstruction is crucial for immersive AR/VR but is hard to achieve with traditional photogrammetry and mesh-based pipelines due to latency and limited scalability. Neural Radiance Fields (NeRF) enable high-quality novel view synthesis but suffer from long training and slow rendering, while Gaussian Splatting (GS) achieves real-time rendering at the cost of heavy preprocessing and me
Roten till cancer? Cancer är en ledande orsak till en stor mängd dödsfall i världen och därför en fruktad sjukdom. Forskningen gör dock framsteg och man kommer allt närmre svaren på gåtorna. På senare år har det föreslagits att en speciell typ av celler, cancerstamceller, är drivande och ligger bakom flera av cancersjukdomarnas egenskaper. Alla organismer är uppbyggda av celler, den stora majoriIn recent years increasing evidence supporting the stem cell hypothesis have emerged and cancer stem cells (CSCs) have been reported to have been isolated in a wide variety of cancers. This CSC population has been attributed to contribute to the therapeutic resistance of many cancers and it is thus of great interest to find new therapeutic options targeting these cells. In ileal carcinoids however
Priming effects have gotten revived interest in the last decade due to the concerns of global warming. Priming are defined as an increase in decomposition of soil organic matter due to the addition of organic or mineral substances. The worldwide used herbicide glyphosate is rapidly degraded by microorganisms. Hence, it might give rise to priming effects in soils. This was tested by adding glyphosa
This study contributes to fill the gap in the existing community health worker literature by offering a more nuanced perspective on performance motivation of healthcare workers from rural South Africa. Specifically, it focuses on the various work incentives and perceived organization support that shape work performance of healthcare workers and, therefore, organizational effectiveness. By followin
The extent of today's land degradation and desertification in the arid, semi-arid. and sub humid regions of China is a serious threat to the social and economic development in these areas. A national programme for monitoring and classification of drylands has been implemented by the Chinese Academy of Science. Areas are classified into degrees of desertification on the basis of vegetation cove
