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No Difference in Conversion Rate to Hip Arthroplasty After Intramedullary Nail or Sliding Hip Screw for Extracapsular Hip Fractures : An Observational Cohort Study of 19,604 Individuals

BACKGROUND: The widespread use of intramedullary nails (IMNs) compared with sliding hip screws (SHSs) in extracapsular hip fractures (AO/OTA 31-A1, 31-A2, 31-A3) has been questioned because of a higher complication rate, although the outcome might have improved through more recent implant designs and the learning curve. This study aimed to investigate if there is a difference with regard to the cu

Excess mortality by suicide in high-risk subgroups of suicide attempters: a prospective study of standardised mortality rates in suicide attempters examined at a medical emergency inpatient unit

Objectives The primary aim of the present study was to investigate the putative excess mortality by suicide in suicide attempters. As a secondary aim, we investigate excess mortality in specific, clinically relevant subgroups: individuals with repeated suicide attempts (RA); individuals who used violent method at the attempt (VA); and those who scored high on the Suicide Intent Scale (HS) at the t

Blood lead levels and risk of atherosclerosis in the carotid artery : Results from a swedish cohort

BACKGROUND: Lead exposure has been associated with increased incidence of adverse clinical cardiovascular outcomes. Atherosclerosis has been suggested as one of the underlying mechanisms, and findings from experimental studies support this, but human data are scarce. OBJECTIVES: Our objective was to determine the association between environmental lead exposure based on blood lead (B-Pb) concentrat

Interlinkages, Integration and Coherence

This chapter focuses on the national level and studies interlinkages, institutional integration and policy coherence in the context of the 2030 Agenda for Sustainable Development and the Sustainable Development Goals. After defining key terms, the chapter reviews how perspectives on interlinkages have shaped a new discourse, followed by an analysis of the steering effects of the global goals on in

Accuracy of patient-specific I-131 dosimetry using hybrid whole-body planar-SPECT/CT I-123 and I-131 imaging

Purpose: This study aimed to assess the accuracy of patient-specific absorbed dose calculations for tumours and organs at risk in radiopharmaceutical therapy planning, utilizing hybrid planar-SPECT/CT imaging. Methods: Three Monte Carlo (MC) simulated digital patient phantoms were created, with time-activity data for mIBG labelled to I-123 (LEHR and ME collimators) and I-131 (HE collimator). The s

Rare manifestations and malignancies in tuberous sclerosis complex : findings from the TuberOus SClerosis registry to increAse disease awareness (TOSCA)

BACKGROUND: Tuberous sclerosis complex (TSC) is a rare multisystem autosomal dominant disorder caused by pathogenic variants in either the TSC1 or TSC2 gene. Common manifestations of TSC have been grouped into major and minor clinical diagnostic criteria and assessed in clinical routine workup. However, case studies point towards the existence of rare disease manifestations and to the potential as

Type 2 diabetes exacerbates changes in blood pressure-independent arterial stiffness : cross-sectional and longitudinal evidence from the SUMMIT study

Greater central artery stiffness is observed in people with type 2 diabetes (T2DM). Elevated blood pressure (BP) and altered arterial wall structure/composition in T2DM are generally considered as main drivers for this alteration. However, because conventional arterial stiffness measures are BP-dependent and as such an influence of BP remains in a measure, it is unclear if greater central artery s

HLA Class II (DR, DQ, DP) Genes Were Separately Associated With the Progression From Seroconversion to Onset of Type 1 Diabetes Among Participants in Two Diabetes Prevention Trials (DPT-1 and TN07)

OBJECTIVE: To explore associations of HLA class II genes (HLAII) with the progression of islet autoimmunity from asymptomatic to symptomatic type 1 diabetes (T1D).RESEARCH DESIGN AND METHODS: Next-generation targeted sequencing was used to genotype eight HLAII genes (DQA1, DQB1, DRB1, DRB3, DRB4, DRB5, DPA1, DPB1) in 1,216 participants from the Diabetes Prevention Trial-1 and Randomized Diabetes P

The Free Hormone Hypothesis: Is Free Serum25-Hydroxyvitamin D a Better Marker for Bone Mineral Density in Older Women?

It is presently unclear whether free serum 25 hydroxyvitamin D (S 25(OH)D) better reflects bone health than total S 25(OH)D. We have previously shown that summer total S 25(OH)D values are more useful to predict bone mineral density (BMD) than winter values. Our objective was therefore to compare the relative importance of free and total S 25(OH)D for BMD by season. BMD was measured by dual energy

Atrial fibrillatory rate and risk of left atrial thrombus in atrial fibrillation.

ims In atrial fibrillation (AF), a relation between electrocardiogram (ECG) fibrillatory wave amplitude and thrombus formation has been sought for long with conflicting results. In contrast, the possible relation between atrial fibrillatory rate obtained from the surface ECG and left atrial thrombus formation in patients with AF is unknown and was consequently evaluated in this study. Methods and

Proshchenkoite-(Y) from Russia - a new mineral species in the vicanite group: descriptive data and crystal structure

A REE-bearing fluorosilicate from the Tommot REE-Nb deposit in Yakutia, Russia, described without a name in 1966, is characterized here as a new species, proshchenkoite-(Y), of the vicanite group of borosilicates. Wavelength-dispersive electron probe analyses gave the following empirical formula: (Y3.70REE7.54Ca1.55Na1.16Mn0.77Th0.10Pb0.01)(Sigma 14.83)(Fe0.832+M0.15Ti0.02)(Sigma 1.00)Ca-1.00 (P0.

Revascularisation of renal artery stenosis caused by fibromuscular dysplasia: effects on blood pressure during 7-year follow-up are influenced by duration of hypertension and branch artery stenosis

Fibromuscular dysplasia (FMD) mainly affects renal arteries. Percutaneous transluminal renal angioplasty (PTRA) and surgery are effective treatments, but longtime follow-up is lacking. Retrospective follow-up for 7.0 +/- 4.7 years of 69 consecutive patients ( age 44 +/- 13 years) treated for hypertension due to FMD, 59 patients underwent PTRA and eight patients surgery. In two patients no PTRA was

6-Thioguanine therapy in Crohn's disease-Observational data in Swedish patients

Background and aims. Adverse events (AE) leading to discontinuation or dose-reduction of thiopurine therapy (TP) occur in 9-28% of patients with inflammatory bowel disease. 6-Thioguanine (6-TG) has been proposed as an alternative treatment in patients intolerant for azathioprine (AZA), but some concerns have been raised about drug safety. Methods. We evaluated in a prospective manner the tolerance

Bone-targeted radium-223 in symptomatic, hormone-refractory prostate cancer: a randomised, multicentre, placebo-controlled phase II study

Background The alpha-emitter radium-223 (Ra-223) is a bone-seeking radionuclide studied as a new treatment for patients with bone metastases from hormone-refractory prostate cancer. We aimed to study mature outcomes from a randomised, multicentre, phase II study of Ra-223. Methods Patients with hormone-refractory prostate cancer and bone pain needing external-beam radiotherapy were assigned to fou

‘All out for shale’ : the mental health impacts of the government’s fracking policy: evidence from Lancashire, England

Shale gas extraction commonly known as fracking had support from the UK government with their ‘all out for shale’ policy. Despite this industry has struggled to establish itself mainly due to strong opposition from communities concerned about environmental and health impacts. Most research into the impacts of fracking is concerned with either environmental degradation or physical health impacts wh

Klubba, Puck och Eget Kapital

Titel: Klubba, Puck och Eget kapital - En rapport om Svenska Ishockeyförbundets ekonomiska licenskrav Seminariedatum: 2020-06-03 Kurs: FEKH69, Examensarbete i redovisning, Företagsekonomi, 15 högskolepoäng Författare: Oscar Lundquist, Erik Sandahl & Lukas Öberg Handledare: Gert Paulsson Nyckelord: Ishockey, licenskrav, eget kapital, nyckeltal, konkursprediktion, effektivitet. Syfte: Denna uTitle: Stick, Puck and Shareholders' Equity - A report of the Swedish Ice Hockey Association's financial license requirements Seminar date: 2020-06-03 Course: FEKH69, Degree Project Undergraduate level, Business Administration, 15 ECTS Authors: Oscar Lundquist, Erik Sandahl & Lukas Öberg Advisor: Gert Paulsson Key words: Ice Hockey, license requirements, shareholders' equity, fi

High resolution imaging observations of exoplanet host stars

Stjärnor sägs vara astronomins tidskapsel, genom att studera stjärnor kan vi bättre förstå många fenomen. Stjärnor är en viktig del av vårt universum från det att de skapas till det att de dör. De berikar vårt universum med olika grundämnen som krävs för att planeter ska bildas och för att liv ska uppstå. Det verkar då självklart varför man vill undersöka och förstå alla aspekter kring stjärnbildnThis is a thesis project, analysing data from high-resolution imaging observations, specifically speckle imaging, as a follow up study of exoplanet host stars observed with K2, the second operational phase of the space telescope Kepler. The project was accomplished at NASA Ames research center under the guidance of Rachel A. Matson, during an internship in collaboration with the Swedish National S

Impact is a Two-Way Conversation

Sustainability researchers are facing increasing pressure to improve their scientific communication and to achieve impacts in wider society with their research. Knowledge mobilisation (KMB) is a key component of both challenges, as it relates to efforts undertaken by researchers to achieve impacts with their research. This study seeks to identify some of the KMB practices being undertaken by exper

Arktis och Antarktis föränderliga havsistäcken

Populärvetenskaplig sammanfattning De båda polerna har naturliga variationer med istäckets utbredning. Arktis och Antarktis har väl anpassad biota som klarar av det stränga klimatet och som är beroende av isens säsongsvariationer med att frysa och smälta. Isen spelar även en stor roll vid klimatvariationer och förändringar. Syftet med den här studien är att undersöka vilken isbildning som är mest The polar areas have natural variations in the ice extent. The Arctic and Antarctic environment have well-adapted biota that can handle climate and that are dependent on the seasonal variations of freezing and melting of the ice. The ice also plays a major role in climate changes and climate variability. The aim of this report is to determine the type of ice formation that is most common for the p