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Background Exertional breathlessness is commonly assessed using incremental exercise testing (IET), but reference equations for breathlessness responses are lacking. We aimed to develop reference equations for breathlessness intensity during IET. Methods A retrospective, consecutive cohort study of adults undergoing IET was carried out in Sweden. Exclusion criteria included cardiac or respiratory
PURPOSE: A polygenic risk score (PRS) consisting of 313 common genetic variants (PRS313) is associated with risk of breast cancer and contralateral breast cancer. This study aimed to evaluate the association of the PRS313 with clinicopathologic characteristics of, and survival following, breast cancer.METHODS: Women with invasive breast cancer were included, 98,397 of European ancestry and 12,920
Purpose We evaluated the impact of early integrated palliative care (PC) in patients with newly diagnosed lung and GI cancer. Patients and Methods We randomly assigned patients with newly diagnosed incurable lung or noncolorectal GI cancer to receive either early integrated PC and oncology care (n = 175) or usual care (n = 175) between May 2011 and July 2015. Patients who were assigned to the inte
Purpose Patients' understanding of their illness is key for making informed treatment decisions, yet studies suggest an association between prognostic awareness and worse quality of life (QOL) and mood among patients with advanced cancer. We sought to explore the relationships among prognostic awareness, coping, QOL, and mood in patients with newly diagnosed, incurable cancer. Methods We assessed
Rationale: According to the Global Initiative for Obstructive Lung Disease (GOLD), the FEV1/FVC ratio is used to confirm the presence of airflow obstruction in the diagnosis of chronic obstructive pulmonary disease (COPD), whereas FEV1 percent predicted normal value (FEV1%pred) is used for grading its severity. The STaging of Airflow obstruction by the FEV1/FVC Ratio (STAR), and its prediction of
Lunds universitet rankas som topp-tio i världen inom forskning på detaljhandel och logistik. Helsingborgsregionen delar på förstaplatsen i Sverige vad gäller bästa logistikläge. Det här ger en bra bas för Lunds universitets satsning REAL – Center for Retail and Logistics – på Campus Helsingborg. Detta centrum profilerar sig med hållbarhet, digitalisering och förändrat arbetsliv och lyfter också fr
An autoregressive process with Markov regime is an autoregressive process for which the regression function at each time point is given by a nonobservable Markov chain. In this paper we consider the asymptotic properties of the maximum likelihood estimator in a possibly nonstationary process of this kind for which the hidden state space is compact but not necessarily finite. Consistency and asympt
Popular Abstract in Swedish Formålet var at undersøge samspillet mellem pårørende til svækkede ældre patienter og sygeplejepersonalet i akutte hospitalsafdelinger, samt at udvikle og teste et instrument til at undersøge, udfra pårørendes perspektiv, samspillets dimensioner i denne kontekst og associationen mellem samspil og tilfredshed med patientforløbet. Den underliggende antagelse for studiet vThe aim was to investigate collaboration between relatives of frail elderly patients and nurses in acute hospital wards, and to develop and test an instrument to investigate, from the relatives? perspective, dimensions of collaboration in this context and the association between collaboration and satisfaction with the hospital care trajectory. The underpinning assumption for the study was that rel
Popular Abstract in Swedish Idag lagras allt fler kartor digitalt och nya metoder krävs för att förbättra denna digitala hantering. Ett område som studerats under senare tid är automatiska metoder för kartografisk generalisering. Kartografisk generalisering innebär att man förenklar informationen i en karta för att göra den mer lättläst i den önskade skalan. Denna avhandling beskriver en optimerinCartographic generalisation is the process of simplifying a representation to suit the scale and purpose of a map. As such, generalisation has always been a central part in map production. This thesis is a contribution to the ongoing work on automating cartographic generalisation. Two topics are treated: optimisation methods in graphic generalisation, and propagation of updates between cartographi
Planning and scheduling are functions that have large economic impact in the chemical process industry. For integrated sites with many interconnected production areas, obtaining production schedules that respect all production-related constraints is a complex task. One important issue is the constraints due to disturbances in utilities, such as steam and cooling water. These are often site-wide di
This thesis consists of three different essays, all of which have arisen from a practical problem. In the first essay, “Technical efficiency and ownership: The case of booking centers in the Swedish Taxi Market” the purpose is to examine the question of competition on an equal basis between privately and publicly owned booking centers in the Swedish taxi market. One way to answer this question is
To acquire the demand information comprehensively and facilitate demand information reuse, the research of acquisition and expression of user requirements were carried on based on user's cognitive process, ontology and development law of requirements. According to the expression and existing condition of user requirements, the acquisition strategy based on requirements classification was proposed.
Evaluation, prioritization and selection of candidate requirements are of tremendous importance and impact for subsequent software development. Effort, time as well as quality constraints have to be taken into account. Typically, different stakeholders have conflicting priorities and the requirements of all these stakeholders have to be balanced in an appropriate way to ensure maximum value of the
This paper aims to review the development of wastewater treatment operation and control over the last two decades. Due to the authors' background and experiences there is a special emphasis on the Scandinavian perspective. Since the developments in these countries have been in the forefront in the wastewater treatment area we believe that it may give a reasonable view of the progress also in other
Title: Finding optimal logistical hubs for Swedish export - A study of selecting global locations Authors: Cecilia Eskilsson and Fredrik Hansson Tutors: Andreas Norrman, Professor, Department of Industrial Management and Logistics, Faculty of Engineering, Lund University, Oskar Henkow, Lecturer, Department of Business Law, School of Economics and Management, Lund University Henrik Danielsson, He
Syfte: Studiens syfte är att undersöka om det i teorin beskrivs faktorer inom hur man framgångsrikt kommunicerar en förändringsprocess som inte appliceras i praktiken, vilket i så fall kan ligga till grund för att en så stor del av förändringsprocesser inte implementeras. Metod: En kvalitativ tvärsnittsstudie utifrån en deduktiv ansats. Uppsatsens empiriska material insamlades genom semistrukturer
The purpose of this thesis is to explore the factors, circumstances and insights influencing Swedish organizations in their own transitioning process towards AI. The work conducted within this thesis results in a qualitative report where a number of focus areas are reviewed in an attempt to first provide a holistic picture surrounding the definitions, contexts, activities and mindsets involved in
Modern portfolio theory was pioneered by Markowitz who formulated the mean-variance problem, without which any discussion on quantitative approaches to portfolio selection would be incomplete. The framework boils down to finding the expected return $\mu$ and covariance $\Sigma$, after which the solution is proportional to $\Sigma^{-1}\mu$. Although the problem is simple at heart, finding estimates
