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Patients with bone marrow failure and severe thrombocytopenia are frequently given prophylactic platelet transfusion before interventions. The clinical effects of such transfusions, however, are poorly defined. We performed a prospective observational study on patients with bone marrow failure scheduled for prophylactic platelet transfusion before the insertion of a central venous catheter. The ob
The traditional restrictive attitude towards claim for compensation about non-pecuniary harms in both cause law and legislation become weaker even if the theoretically and practically reason behind the old exception-construction remain. This reason can best be explained by the thesis about incommensurability when it comes to compensate for some losses that money cannot compensate. To explain why t
Popular Abstract in Swedish Experimentella data från kollisioner mellan guldjoner vid hög energi har analyserat inom ramen för experimentet PHENIX, som finns vid en av kollisionspunkterna vid ''the Relativistic Heavy-Ion Collider'' på ''Brookhaven National Laboratory'', New York (USA). Kollisioner med tunga joner, så som guld, används i försök till att återskapa de förhållanden som fanns i univerThe properties of the basic building blocks of nuclear matter, the quarks, and their interactions are not known in detail, largely because observations are complicated by the confinement of quarks in composite particles. New insights can be gained from the study of nuclear matter in a deconfined phase, like the form of matter that the Universe consited of early in its evolution according to the Bi
Escherichia coli K1 and Group B Streptococcus (GBS) are the most common bacteria that cause meningitis during the neonatal period. Complement, the first line of defence in the host, acts on these bacteria to opsonize with various components of complement for subsequent presentation to phagocytes. To counteract these opsonization effects, E. coli and GBS bind to the complement regulators C4 binding
The VDR is a prime candidate gene for osteoporosis. Here, we studied three common VDR haplotypes in relation to bone phenotypes in 5014 participants of the global MrOS Study. We also studied the relative expression of the haplotypes in human bone cells. One haplotype was associated with increased fracture risk and differently expressed in primary human bone cells. Introduction: Vitamin D plays an
Disturbed cellular cholesterol homeostasis may lead to accumulation of cholesterol in human atheroma plaques. Cellular cholesterol homeostasis is controlled by the sterol regulatory element-binding transcription factor 2 (SREBF-2) and the SREBF cleavage-activating protein (SCAP). We investigated whole genome expression in a series of human atherosclerotic samples from different vascular territorie
Pneumococcal surface protein A (PspA) is able to elicit antibodies in mice and humans that can protect mice against fatal infection with Streptococcus pneumoniae. It has been observed that immunization with a single family 1 PspA can protect mice against infections with capsular type 3 or 6B strains expressing PspA family 1 or 2. However, several studies have shown that immunity to PspA is less ef
This study examines the role of the Sovereign ESG framework in assessing national progress toward Transformative Change (TC) via environmental, social, and governance metrics. Using data from the World Bank Sovereign ESG Data Portal, we conduct an empirical explorative quantitative study and analyze ESG development across country income groups to identify sustainability challenges and opportunitie
Introduction: Immune checkpoint inhibitors (ICIs) have transformed lung cancer treatment, yet their effectiveness seem restricted to certain patient subsets. Current clinical stratification on the basis of programmed death ligand 1 (PD-L1) expression offers limited predictive value. Given the mechanism of action, directly detecting spatial programmed cell death protein 1 (PD1)–PD-L1 interactions m
Community-acquired pneumonia (CAP) is a significant health threat for adults. Although conjugate vaccines have reduced pneumococcal CAP incidence in children, Streptococcus pneumoniae-related CAP remains prevalent among older adults. The nasopharynx acts as a reservoir for S. pneumoniae, yet the interplay between this pathogen and the nasopharyngeal microbiome during and after pneumonia remains po
ObjectivesThis nested case–control study aimed to investigate the relationship between components of the Swedish food-based dietary guidelines (SDG) from 2015 and the risk of developing rheumatoid arthritis (RA).MethodsData were obtained from the prospective Malmö Diet and Cancer Study (MDCS) conducted 1991–1996. Diet was assessed at baseline using a validated diet history method. Incident RA case
The central theme of this thesis is anthropogenic climate change; governments' inability to create an effective, inclusive response mechanism that manages to mitigate anthropogenic emissions; and advocates efforts to coerce States to act by invoking State responsibility in adjudicatory dispute settlement processes. States' failure to act in accordance with scientific risk assessments and
Brevmall Postadress Lunds universitet, Box 117, 221 00 Lund Besöksadress Medicon Village, Scheelevägen 1 Telefon 0730 683 698, 046-2220305 E-post sara.naurin@fs.lu.se, johanna.mellgren@fs.lu.se Webbadress www.fs.lu.se Forskningsserv ice Hanteringsordning vid Lunds universitet för projektansökningar till Stiftelsen Marcus och Amalia Wallenbergs Minnesfond och Marianne och Marcus Wallenbergs Stiftel
Lund University in brief 2022 Lund University 2022 | EDUCATION, RESEARCH AND COLLABORATION SINCE 1666 A WORLD-CLASS UNIVERSITY To understand, explain and improve Lund University was founded in 1666 and, ever since, has been a centre of culture and learning. One of our strengths is our unique disciplinary range and our ability to generate boundary-crossing collaboration. Student influence, internat
https://www.medarbetarwebben.lu.se/sites/medarbetarwebben.lu.se/files/2022-05/Presentationbrochure-2022-ENG.pdf - 2026-07-17
This thesis explores current trends in social and political organising in Northern Syria, in areas controlled by the PYD. The research is built on discussions between eight participants from the Syrian Kurdish-speaking community living in the areas. While most discourses on Syria and the Kurdish-speaking community have a macro-political focus and produce racialising descriptions of “Kurdishness” i
The impact of plastic on the environment has been acknowledged on different levels, among others various NGOs around the world. These NGOs are known to aim for a reduction of plastic ending up in nature and more specifically the ocean. Plastic has been instrumental to the development of modern societies since the 1950s as the properties of the material enables it to be used for various purposes. T
Covid-19-pandemin innebar att många organisationer skickade hem sina medarbetare för att arbeta på distans i syfte att minska smittspridningen. För att kunna sköta verksamheten blev det viktigt att medarbetarna kunde fortsätta arbeta och samarbeta på distans. Därför är det viktigt att de IT-system som möjliggör samarbete också används för att samarbeta. Datainsamlingen till vår forskningsstudi
