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This Bachelor Thesis discusses the American government’s initial fiscal response to the Covid-19 pandemic, the Cares Act, and investigates how the different disposition of money in the two States Mississippi and Alabama has affected entrepreneurship. This comparison is made through a descriptive analysis of how the two states, have distributed, focused and used their Cares Act capital. It is found
The impact of plastic on the environment has been acknowledged on different levels, among others various NGOs around the world. These NGOs are known to aim for a reduction of plastic ending up in nature and more specifically the ocean. Plastic has been instrumental to the development of modern societies since the 1950s as the properties of the material enables it to be used for various purposes. T
Making Europe climate neutral by 2050 is the primary goal of the European Green Deal. This goal has given rise to sustainable finance and action plans for financing sustainable growth. Such commitment is ensured by the legal initiatives put forward by the Commission. The Non-Financial Reporting Directive introduced the requirements for some firms to produce a sustainability report based on disclos
Populärvetenskaplig sammanfattning En förändring i det rådande klimatet med en temperaturhöjning på grund av en ökad atmosfärisk CO₂-koncentration kan komma att ha en påverkan på skogar över hela jordgloben. Trädarter som är anpassade till ett visst klimat kan komma att spridas norrut då klimatet kan vara mer passande i framtiden. Detta medför risken att lövträd från central Europa kan konkurrera A climate change will affect the forests around the globe; there may be competitions for available resources that are needed for growth and dispersal. Europe is supposed to be more sensitive and may experience a greater influence than many other regions. As an additional effect of climate change extreme weather events will be more frequent e.g. drought and extreme precipitation that will cause flo
Ethiopia is implementing a Productive Safety Net Program (PSNP) as of 2005, claimed to be the largest social protection program in Africa, which sets out to link relief to development and curb the country’s long over dependence on food aid. This research,thus explores the theoretical framework regarding social protection programs and their ability to bridge the gap between relief and development b
With the ongoing climate collapse, there is a need for a capital switch, rerouting investments into low carbon infrastructure. Green bonds are a new financial vehicle aimed to facilitate this transition. Through signaling the issuers’ intent to use the proceeds of the bonds towards environmentally beneficial activities, they increase transparency and allow investors to better calculate risks while
Sepsis remains a major clinical challenge due to the limited efficacy of existing therapies in controlling excessive inflammation. The engineered stapled peptide sHVF18, derived from an evolutionarily conserved thrombin innate fold, binds both lipopolysaccharide (LPS) and the LPS-binding groove of CD14, enabling dual targeting of bacterial components and host immune signaling. To define structural
The role of the gaseous messengers NO and CO for β-cell function and survival is controversial. We examined this issue in the hyperglycemic-hyperinsulinemic ob/ob mouse, an animal model of type 2 obese diabetes, by studying islets from obese vs lean mice regarding glucose-stimulated insulin release in relation to islet NO and CO production and the influence of modulating peptide hormones. Glucose-
Disturbed cellular cholesterol homeostasis may lead to accumulation of cholesterol in human atheroma plaques. Cellular cholesterol homeostasis is controlled by the sterol regulatory element-binding transcription factor 2 (SREBF-2) and the SREBF cleavage-activating protein (SCAP). We investigated whole genome expression in a series of human atherosclerotic samples from different vascular territorie
Introduction: Immune checkpoint inhibitors (ICIs) have transformed lung cancer treatment, yet their effectiveness seem restricted to certain patient subsets. Current clinical stratification on the basis of programmed death ligand 1 (PD-L1) expression offers limited predictive value. Given the mechanism of action, directly detecting spatial programmed cell death protein 1 (PD1)–PD-L1 interactions m
Community-acquired pneumonia (CAP) is a significant health threat for adults. Although conjugate vaccines have reduced pneumococcal CAP incidence in children, Streptococcus pneumoniae-related CAP remains prevalent among older adults. The nasopharynx acts as a reservoir for S. pneumoniae, yet the interplay between this pathogen and the nasopharyngeal microbiome during and after pneumonia remains po
ObjectivesThis nested case–control study aimed to investigate the relationship between components of the Swedish food-based dietary guidelines (SDG) from 2015 and the risk of developing rheumatoid arthritis (RA).MethodsData were obtained from the prospective Malmö Diet and Cancer Study (MDCS) conducted 1991–1996. Diet was assessed at baseline using a validated diet history method. Incident RA case
The International Human Papillomavirus (HPV) Reference Center launches annual global HPV genotyping proficiency panels to enhance the precision and international standardization of HPV genotyping services. This study aims to assess the proficiency levels achieved in the global HPV genotyping proficiency panels conducted in 2022 and 2023, and to evaluate trends in performance over time. The profici
This study examines the role of the Sovereign ESG framework in assessing national progress toward Transformative Change (TC) via environmental, social, and governance metrics. Using data from the World Bank Sovereign ESG Data Portal, we conduct an empirical explorative quantitative study and analyze ESG development across country income groups to identify sustainability challenges and opportunitie
In laboratory medicine, much effort has been put into analytical quality in the past decades, making this medical profession one of the most standardized with the lowest rates of error. However, even the best analytical quality cannot compensate for errors or low quality in the pre or postanalytical phase of the total testing process. Guidelines for data reporting focus solely on defined data elem
BACKGROUND: After breast-conserving surgery, radiotherapy reduces recurrence and breast cancer death, but it may do so more for some groups of women than for others. We describe the absolute magnitude of these reductions according to various prognostic and other patient characteristics, and relate the absolute reduction in 15-year risk of breast cancer death to the absolute reduction in 10-year re
