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Recent calls for a revision of standard evolutionary theory (SET) are based partly on arguments about the reciprocal causation. Reciprocal causation means that cause–effect relationships are bi-directional, as a cause could later become an effect and vice versa. Such dynamic cause-effect relationships raise questions about the distinction between proximate and ultimate causes, as originally formul

Operation med konstgjorda ledproteser i höft och knä ger generellt mycket lyckade resultat. Fortfarande förekommer dock lossning och slitage av komponenterna som ett problem, och alla patienter blir inte fullt nöjda. I ett flertal forskningsprojekt studerar vi faktorer av betydelse för fixation och funktion av proteskomponenterna. Vi utvärderar hur man optimerar de biomekaniska ledförhållandena viTotal joint replacements, both in the hip and knee, are generally very successful operations. Still, however, component loosening as well as wear remains a problem, and all patients are not fully satisfied with their new joint. In a number of ongoing investigations, we are studying different factors involved in the fixation and function of the prosthesis components. We are exploring how to optimiz

Evaluating the effect of measurement errors on either adaptive or simultaneous control charts has been a topic of interest for the researchers in the recent years. Nevertheless, the effect of measurement errors on both adaptive and simultaneous monitoring control charts has not been considered yet. In this paper, through extensive numerical studies, we evaluate the effect of measurement errors on

Cyclic nucleotide phosphodiesterases (PDEs) are important regulators of signal transduction processes mediated by cAMP and cGMP. One PDE family member, PDE3B, plays an important role in the regulation of a variety of metabolic processes such as lipolysis and insulin secretion. In this study, the cellular localization and the role of PDE3B in the regulation of triglyceride, cholesterol and glucose

The Lund Cardiac MR Group at the Department of Clinical Physiology, Lund University was established 1999 by professor Håkan Arheden and is led by a steering committee consisting of professors Håkan Arheden, Henrik Engblom, Anthony Aletras, associate professors Einar Heiberg, Ellen Ostenfeld, Erik Hedström, Katarina Steding-Ehrenborg and Johannes Töger. The group performs clinically integrated res

The effective management of end-users and their requirements in construction projects can bring a number of benefits, for example more satisfied and less critical end-users in terms of both the product and project. Building occupants are however continually changing and with that their needs. It is thereby a challenge to understand what brings value for both known and unknown end-users. More over

Laboratoriet för metabola störningar och leversjukdomar leds av Philipp Kaldis, som är professor vid Institutionen för kliniska vetenskaper och vice koordinator för Lunds universitets Diabetescentrum (LUDC). Nya data tyder på att upp till 30% av befolkningen lider av leversjukdomar inklusive icke-alkoholorsakad fettleversjukdom (NAFLD), som kan vidareutvecklas till icke-alkoholorsakad steatohepatiThe metabolic disorders and liver disease laboratory is headed by Philipp Kaldis, who is a Professor in the Department of Clinical Sciences and a vice-coordinator of the Lund University Diabetes Centre (LUDC). Recent data suggests that up to 30% of the population suffers from liver diseases including non-alcoholic fatty liver disease (NAFLD), which can further develop to non-alcoholic steatohepati

After several years of disussions, tests, investigations and additional tests, the suppliers and retailers within the Swedish business sector for food and commodities formed a jointly owned, non-profit company in 1997, which subsequently started in physical operations in 2000. This company, Svenska Retursystem AB (www.retursystem.se), is now responsible for introducing returnable transport packagi

MultiPark är ett translationellt forskningsnätverk som sträcker sig från preklinisk forskning till studier av livssituationer för patienter med Alzheimers och Parkinsons sjukdom samt relaterade hjärnsjukdomar. Vi syftar inte bara till att förbättra patienternas kroppsfunktion utan även deras aktivitet och delaktighet. MultiPark bygger på ett starkt samarbete mellan Lunds universitet och Skånes uniMultiPark (Multidisciplinary research focused on Parkinson's disease) is a translational programme that ranges from experimental pre-clinical research to studies on the life situation of patients with neurodegenerative disorders. Our programme not only aims at improving the overall function of patients, but also their acitivity and participation. This initiative relies on solid interactions betwee

Epilepsy is a devastating neurological disorder characterized by synchronous neuronal activity, which manifests as epileptic seizures. It usually develops after an initial insult, such as head trauma or stroke, which triggers the epileptogenic process. During epileptogenesis, the affected brain regions undergo multiple changes in connectivity and gene expression, and among the most affected genes