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In unsparing efforts to find the hidden primaries, second primary cancers (SPCs) unrelated to cancer of unknown primary (CUP) are found. The detection rates of SPCs after CUP can be considered as measures for the effectiveness of modern diagnostic techniques in finding tumors. We aimed to compare the rates of specific SPCs found after the work-up of CUP and the more sign/symptom-directed diagnosti
Background: Outcomes for many cancer forms are associated with socioeconomic status (SES). We investigated if SES was associated with management and mortality in men with high risk prostate cancer. Material and methods: A nation-wide population-based cohort in Prostate Cancer Data Base Sweden (PCBaSe), a merged database including data on incident prostate cancer identified in the National Prostate
HIV-1 infects target cells by binding to CD4 and a chemokine receptor, most commonly CCR5. CXCR4 is a frequent alternative coreceptor (CoR) in subtype B and D HIV-1 infection, but the importance of many other alternative CoR remains elusive. We have analyzed HIV-1 envelope proteins (Env) from 66 individuals infected with the major subtypes of HIV-1 to determine if virus entry into highly permissiv
Exposure to isocyanates is known to have respiratory effects in workers and therefore it is essential to monitor the occupational exposure. An earlier study of a continuous foaming plant using toluene diisocyanate (TDI) showed that the exposure to isocyanates can be high. Since then several preventive actions were implemented at the plant. The aim of this study was to observe the effect of these a
The global methylation profile and the mutational status of 633 specific epigenetic regulators were analyzed in the pediatric tumor clear cell sarcoma of the kidney (CCSK). Methylation array analyses of 30 CCSKs revealed CCSK tumor DNA to be globally hypermethylated compared to Wilms tumor, normal fetal kidney, and adult kidney. The aberrant methylation pattern of CCSKs was associated with activat
The combination of features from the public and private sectors in jointly owned companies imposes challenges to the governance and control mechanisms of these organisations, which have been criticised for lacking accountability. Where there is fragmented ownership, the interests of different owners need to be coordinated. The aim of this article is to consider how such companies can be governed i
This article studies continued childbearing and union stability among "power couples," or dual-career couples. The determinants of these events are analysed multivariately using longitudinal data on couples from population registers in Sweden, 1991–2005. Power couples are identified using their levels and fields of education, and their sectors of employment. Income and other variables are controll
Metabolic complications are prevalent in individuals treated with cranial radiotherapy (CRT) for childhood acute lymphoblastic leukemia (ALL). The hypothalamus is a master regulator of endocrine and metabolic control. The aim of this study was to investigate whether the hypothalamic volume would be associated to metabolic parameters in ALL survivors. Thirty-eight (21 women) survivors participated
BACKGROUND: The 1061delC single-nucleotide polymorphism (SNP) has been reported mostly in the context of the common A(2)[A201] allele and typically produces an A(2) phenotype. This study evaluated new A(weak) alleles, each containing 1061delC. STUDY DESIGN AND METHODS: Twenty samples were referred to our laboratory for analysis due to suspected A(weak) phenotypes originally detected at the referri
This study examines elaborate prayer practices among peasant communities in late medieval Sweden. The work focuses on the perspectives of ideals and practices, namely the standards of prayer, devotional prayer, and prayer in times of need and prayer cultures.
Popular Abstract in Swedish Fältskiktet gör skillnaden! Dynamiken av näringsämnen och organiskt material i bokskogens övre markskikt Frida Andreasson, Växtekologi och systematik, Lunds universitet Det övre markskiktet i bokskogen är markens mest biologiskt aktiva del. Därför är kunskapen om denna del av marken, dess egenskaper och kemi, angelägen. Särskilt viktig är kunskapen om mineraliseringeThe objective of this thesis was to quantify differences between adjacent patches with and without ground flora of Deschampsia flexuosa L. Trin or Anemone nemorosa L. in two acid European beech (Fagus sylvatica L.) forest floors in south-west of Sweden. The studies included soil properties and chemistry, N mineralisation and bioavailability of dissolved organic carbon (DOC), in soil leachates (SL)
The study accounts for recent developments in corporate voluntarism and assesses the evolving corporate social responsibility (CSR) regime. CSR proposes a new norm for how large businesses should approach complexity in a modern economy. The first chapter anchors the CSR discussion in a company law and corporate governance context. Emphasis is placed on managerial duties and the British Review of C
