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Background: It has been established that patients with chronic rhinosinusitis with nasal polyps (CRSwNP) often have co-existing asthma. Objective: We aimed to test two hypotheses: (i) upper and lower airway inflammation in CRSwNP is uniform in agreement with the united airways concept; and (ii) bronchial inflammation exists in all CRSwNP patients irrespective of clinical asthma status. Methods: We
Relaxant effects of acetylcholine (ACh), histamine, calcitonin gene‐related peptide (CGRP) and the calcium ionophore A23187 were examined in rat femoral (Ø ≅ 0.2 mm), mesenteric (0.2 mm), intrarenal (0.2 mm) and hepatic (0.3 mm) arteries, and aorta (2 mm). Acetylcholine elicited an endothelium‐dependent relaxation in all arteries. Histamine induced an endothelium‐dependent relaxation in aorta, and
In Japan, rising costs have impacted the framework of maintaining an efficient and effective healthcare system. Today, urgent implementation of programs to address this need have led to a rebuilding of the entire approach of medical evaluation and clinical care. Recent developments in clinical proteomics based on mass spectrometry (MS) for identifying, sequencing, and quantifying disease-relevant
The functional separation of risk assessment and risk management has long been at the heart of risk analysis structures. Equally long it has been criticized for creating technocratic risk management due to valuations being done in the risk assessment to which the stakeholders do not have access. The criticism has mostly been of an ethical nature. Arguably, in separating risk assessment and risk ma
Next-generation sequencing technologies are making it possible to study the role of rare variants in human disease. Many studies balance statistical power with cost-effectiveness by (a) sampling from phenotypic extremes and (b) utilizing a two-stage design. Two-stage designs include a broad-based discovery phase and selection of a subset of potential causal genes/variants to be further examined in
Despite increasing evidence suggesting the cerebellum works in concert with the cortex and basal ganglia, the nature of the reciprocal interactions between these three brain regions remains unclear. This consensus paper gathers diverse recent views on a variety of important roles played by the cerebellum within the cerebello-basal ganglia-thalamo-cortical system across a range of motor and cogniti
Problem/ Background: The study leans on nationalism and globalization debate in the schools of cultural studies and feminist sociological research. The study discusses how gender is constructed in frames of nationalist projects and identity. We concentrate on the situation in Finland in the late 1990s. The question is examined through application of discourse analysis, focused on narratives of thr
In this work a simultaneous localisation and mapping system, SLAM, has been constructed which can incorporate inertial measurement unit, IMU, data such as accelerometer and gyroscope data to estimate the metric scale and the relationship to the gravity vector of the SLAM solution. The system can perform accurate pose predictions at 100Hz based on IMU data and previous camera poses. An improved KLT
In October 2016 the European Border and Coast Guard [EBCG] was installed as the new institutional structure responsible for border management. In contrast to its predecessor Frontex, the EBCG consists not only of an agency but also of the respective national authorities, responsible for border management and coastguard functions. A better understanding of the creation of the EBCG is needed because
The impact of the UK’s decision to leave the EU has received a lot of attention in scientific research in recent years. The effect of Brexit on many different variables and factors related to financial markets and general economy has been studied extensively. Corporate credit risk is, however, an area which did not receive as much attention. This study therefore focuses on the quantification of th
Exploitation of alum shale is a controversial subject in Sweden due to the history of pollution of the environment and groundwater, from past mining industries. The extraction of vanadium from alum shale is no different. Nevertheless the metal is a valuable resource used in tools, building, industries and aerospace materials. A look to the future reveals that vanadium may play a role in renewable
The understanding of the link between the water, sanitation and hygiene (WASH) sector and gender has been extensively researched and is widely accepted as foundational for achieving safe and equal provision of WASH-facilities. Interventions aimed at improvements in the sector are common in low- and middle-income countries, however, there is a limited number of approaches for measuring their outcom
The use of force plays a major role in achieving foreign policy goals. States have resorted to engaging maritime security zones, including naval blockades and maritime exclusion zones, to put pressure on the enemy. In establishing these zones, States are in effect exercising security jurisdiction at sea. Naval blockades aim to prevent sea traffic to and from enemy ports and are enforced through se
Rwanda is endeavouring to deal with its evil past of internal war and genocide to enable a peaceful future. Conflicts between Tutsis and Hutus dominate the Rwandan history. An estimated one million persons were massacred during the 1994 genocide directed against Tutsis and moderate Hutus. Those who survived suffer from physical and psychological wounds. This is equally true for the survivors of wa
Since January 2002, a Swedish citizen has been detained at the U.S. Naval Base at Guantanamo Bay in Cuba. He was captured in Pakistan during the post-September 11 war between Afghanistan and the United States and subsequently brought to Guantanamo, where he has now passed his two years imprisonment. The U.S. has pronounced that it cannot determine how dangerous he is because he is not answering qu
This thesis deals with collusion risks in e-commerce markets based on an analysis of economic theory on structural factors facilitating collusion and empirical findings from studies and case law. It further offers an analysis of the legal status of any such collusion and a discussion on competition policy in relation to it. Whereas the legal rules governing collusion in Article 81(1) of the EC Tre
Kosovo was administered by the UN for almost ten years before unilaterally declaring its independence on the 17th of February 2008. In order to gain support from some major international political players, the declaration of independence was made in line with a number of requirements, including continued external presences, resulting in a ''supervised independence''. These requirem
There are approximately 42 million people around the world suffering from HIV/AIDS, 75% of them are living in Sub-Saharan Africa. HIV/AIDS is a raging epidemic in Africa even though the routes of transmission are "easy" to avoid. In the battle against HIV/AIDS there are many aspect to concider. In the Bachelor thesis I intend to argue for a coneection between poverty, education human cap
