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Two web-based dietary assessment tools have been developed for use in large-scale studies: the Riksmaten method (4-d food record) and MiniMeal-Q (food-frequency method). The aim of the present study was to examine the ability of these methods to capture energy intake against objectively measured total energy expenditure (TEE) with the doubly labelled water technique (TEEDLW), and to compare report
Lymphocyte lineage specification and commitment requires the activation of lineage-specific genes and repression of alternative lineage genes, respectively. The mechanisms governing alternative lineage gene repression and commitment in lymphocytes are largely unknown. In this study, we demonstrate that Ezh2, which represses gene expression through methylation of histone 3 lysine 27, was essential
Background: A psychosocial dementia care programme for challenging behaviour (DEMBASE®) was developed in collaboration with a Swedish BPSD-registry team for in-home care services use in Japan. The programme consisted of a web-based tool for the continued assessment of challenging behaviours and interdisciplinary discussion meetings. Effectiveness of the adapted programme was verified through a clu
BACKGROUND: Obesity is positively associated with colorectal cancer. Recently, body size subtypes categorised by the prevalence of hyperinsulinaemia have been defined, and metabolically healthy overweight/obese individuals (without hyperinsulinaemia) have been suggested to be at lower risk of cardiovascular disease than their metabolically unhealthy (hyperinsulinaemic) overweight/obese counterpart
Popular Abstract in Swedish Denna avhandling bygger på ett studium av romerska glaskärl funna på icke-romerska/inhemska fyndorter — huvudsakligen tillhörande den romerska järnåldern (0–400 e.Kr.) — bortom Hadrianus mur i norra Britannien. Romerska glaskärl har påträffats på inalles 60 fyndorter, varav en stor del utgörs av bosättningar av skilda slag, och endast en liten del härrör från gravar. SoThis thesis is based on a study of Roman glass vessels found on non-Roman/native sites - chiefly of Roman Iron Age date (AD 0-400) - beyond Hadrian’s Wall in northern Britain. Roman glass vessels have been discovered on 60 sites in total, the majority of which are settlements of various types, and only a minor part are graves. As a consequence of this, the greater part of the material is strongly
Description of the paper – e.g. topic, research question, objective, purpose, value, conceptual or theoretical framework, state of the art: Adult learning is a subject of ever growing interest, as the population of persons 65 and older grows in industrialised countries. By 2010 the number of retired persons in the European Union will be almost twice as large as in 1995 (Ilmarinen & Costa, 2000
Mantle cell lymphoma (MCL) is characterized by marked differences in outcome, emphasizing the need for strong prognostic biomarkers. Here, we explore expression patterns and prognostic relevance of circular RNAs (circRNAs), a group of endogenous non-coding RNA molecules, in MCL. We profiled the circRNA expression landscape using RNA-sequencing and explored the prognostic potential of 40 abundant c
The retinoblastoma gene product (pRb) is involved in both cell cycle regulation and cell differentiation. pRb may have dual functions during cell differentiation: partly by promoting a cell cycle brake at G(1) and also by interacting with tissue-specific transcription factors. We recently showed that pRb mediates differentiation of leukemic cell lines involving mechanisms other than the induction
Background: Physical meetings are favoured in social care and home health service in Sweden, both when it comes to internal meetings or home visits at citizens residence. During the pandemic, physical meetings were supposed to decrease as much as possible to avoid the virus to spread. One solution was to digitize as many meetings as possible. Transforming meetings from physical to digital is not w
In recent years, several advances have been achieved in breast cancer (BC) classification and treatment. However, overdiagnosis, overtreatment, and recurrent disease are still significant causes of complication and death. Here, we present the development of a protocol aimed at parallel transcriptome and proteome analysis of BC tissue samples using mass spectrometry, via Data Dependent and Independ
On-demand droplet generation from a continuously flowing stream of aqueous phase has profound applications in dropletbased microfluidics for rare event encapsulation studies. Here, we present acoustic relocation-based droplet generation from co-flowing immiscible fluids in an on-demand manner using bulk acoustic wave (BAW). After on-demand droplet generation, droplets are isolated using the same a
Background: Prenatal exposure to mixtures of endocrine disrupting chemicals (EDC) has the potential to disrupt human metabolism. Prenatal periods are especially sensitive as many developmental processes are regulated by hormones. Prenatal exposure to EDCs has inconsistently been associated with children's body mass index (BMI) and obesity. The objective of this study was to investigate if prenatal
This study aims to investigate the effects of an optimized sowing calendar for wheat over a surface irrigation scheme in the semi-arid region of Haouz (Morocco) on irrigation water requirements, crop growth and development and on yield. For that, a scenario-based simulation approach based on the covariance matrix adaptation–evolution strategy (CMA-ES) was proposed to optimize both the spatiotempor
OBJECTIVE: To examine whether iron intake and genetically determined iron overload interact in predisposing to the development of childhood islet autoimmunity (IA) and type 1 diabetes (T1D).RESEARCH DESIGN AND METHODS: In The Environmental Determinants of Diabetes in the Young (TEDDY) study, 7,770 genetically high-risk children were followed from birth until the development of IA and progression t
AIMS: Our aim was to study the incidence of type 2 diabetes in a population-based cohort of Swedish and Iraqi born individuals, focussing on traditional risk factors, insulin action, insulin secretion and ethnicity.MATERIALS AND METHODS: The cohort consisted of 1164 Iraqi and 693 Swedish-born citizens. We investigated the association between new-onset type 2 diabetes and the predictors including l
