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The aim of this study was to compare the performance of the enzymes produced by Trichoderma reesei Rut C30 and the good extracellular beta-glucosidase-producing mutant Trichoderma atroviride TUB F-1663 to that of commercial preparations in the enzymatic hydrolysis and the simultaneous saccharification and fermentation (SSF) of steam-pretreated spruce (SPS). The concentrated TUB F-1663 enzyme was f
The parameters affecting the lipase activity and operational lifetime during chemo-enzymatic epoxidation of fatty acids were investigated. Immobilized Candida antarctica lipase B (Novozym (R) 435) was incubated in the presence of various reaction components (i.e. toluene, water, H2O2, oleic acid, perpalmitic acid, and epoxystearic acid, respectively) at temperatures between 20 and 60 degrees C fol
During δ-aminolevulinic acid (ALA) based Interstitial Photodynamic Therapy (IPDT) a high light fluence rate is present close to the source fibers. This might induce an unintentional tissue temperature increase of importance for the treatment outcome. In a previous study, we have observed, that the absorption in the tissue increases during the treatment. A system to measure the local tissue tempera
Anaerobic digestion would enable the energy potential of agricultural crop residues such as ley crops and sugar beet tops to be harnessed in Sweden. In the present study, the financial prospects of single-stage fed-batch high-solids digestion on three different scales, 51, 67, and 201 kW, were calculated on the basis of experimental results and observations. In addition to scale, the effects of me
The aryl hydrocarbon receptor (AhR) mediates the toxicity of several environmental contaminants, e.g. 2,3,7,8-tetrachlorodibenzo-p-dioxin, and other halogenated hydrocarbons in vertebrates. This receptor initiates the transcription of several biotransformation enzymes, which in turn are responsible for causing severe harm to biological tissue. Here we describe the isolation and complete characteri
Statistical inference for extremes has been a subject of intensive research over the past couple of decades. One approach is based on modelling exceedances of a random variable over a high threshold with the generalized Pareto (GP) distribution. This has proved to be an important way to apply extreme value theory in practice and is widely used. We introduce a multivariate analogue of the GP distri
The goal of this research is to use hematopoietic cells as vehicles for targeting transgenic immunomodulators to the inflammatory sites. The work presented was focused on the anti-inflammatory soluble TNF receptor. A transmembrane soluble TNF receptor (sTNFR1) construct was expressed in hematopoietic cell lines. ER export was facilitated by addition of a transmembrane (tm) sequence, and constituti
Sodium stearoyl-2 lactylate (SSL) lipid surfactant molecules specifically bind partially hydrolysed oat proteins in aqueous medium and significantly enhance the dispersion stability of oat cereal preparations. The proposed complexation is composition dependent and a greater understanding of the role of both oat proteins and lipid surfactant in the effect was gained with data from high performance
The first ESR spectroscopic evidence of a bimolecular homolytic substitution (SH2) reaction in a 77 K solid phase was presented, where radicals were substituted for the CH3 group of methylsilane and methylgermane (CH3XD3, X = Si, Ge). The radicals were generated by in situ UV-photolysis of CD3I in the solid CH3XD3 in an ESR cavity at 77 K. Using the selectively deuterium labeled compounds, it was
Common diseases such as type 2 diabetes are phenotypically heterogeneous. Obesity is a major risk factor for type 2 diabetes, but patients vary appreciably in body mass index. We hypothesized that the genetic predisposition to the disease may be different in lean (BMI<25 Kg/m(2)) compared to obese cases (BMI >= 30 Kg/m(2)). We performed two case-control genome-wide studies using two accepted cut-o
Preclinical efficacy of continuous delivery of 3,4-dihydroxyphenylalanine (DOPA) with adeno-associated viral (AAV) vectors has recently been documented in animal models of Parkinson's disease (PD). So far, all studies have utilized a mix of two monocistronic vectors expressing either of the two genes, tyrosine hydroxylase (TH) and GTP cyclohydrolase-1 (GCH1), needed for DOPA production. Here, we p
To compare gender-related normal limits for left ventricular (LV) ejection fraction (EF), end-diastolic and end-systolic volumes (EDV and ESV), obtained using two myocardial perfusion-gated single photon emission computed tomography (SPECT) quantification methods. A total of 185 patients were retrospectively selected from a consecutive series of patients examined for coronary artery disease (CAD)
Software release planning can be described as a process consisting of the following three phases: (i) strategic release planning, i.e., the assignment of features to subsequent releases; (ii) operational release planning, i.e., the allocation of resources to tasks within each individual release; and (iii) dynamic re-planning, i.e., the revision of plans in order to handle unexpected changes impose
Background: Lack of professional development opportunities among nursing staff is a major concern in elderly care and has been associated with work dissatisfaction and staff turnover. There is a lack of prospective, controlled studies evaluating the effects of educational interventions on nursing competence and work satisfaction. Objectives: The aim of this study was to evaluate the possible effec
To determine if an inhibition of the endocannabinoid-degrading enzyme fatty acid amide hydrolase (FAAH) can counteract the changes in urodynamic parameters and bladder afferent activities induced by intravesical prostaglandin E2 (PGE2 )-instillation, we studied effects of URB937, a peripherally-restricted FAAH inhibitor, on single-unit afferent activity (SAA) during PGE2 -induced bladder overactiv
This essay aims to study how communication technology, in the form of digital platforms such as Facebook and Twitter, affects citizens' engagement in the autocratic state of Myanmar. The theoretical framework implemented are the theories of participatory politics, as well as Robert Dahl's principles of democracy. Through the methods of case study and process tracing, it was concluded that
Titel: Utvärdering och effektivisering av projekteringsprocesser i ett medelstort byggföretag Författare: Daniel Larsson, Anton Bodin Handledare: Stefan Olander, Universitetslektor, Avdelningen för Byggproduktion, Lunds Tekniska Högskola Examinator: Anne Landin, Professor, Avdelningen för Byggproduktion, Lunds Tekniska Högskola Syfte & problemställning: Syftet är att utreda det utvalda fal
