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Objective: To examine the relation of well-known factors of the metabolic syndrome (MetS) as well as related circulating factors, with risk of colorectal cancer. Methods: We performed a case control study of 306 colorectal cancer cases and 595 matched controls nested in the Northern Sweden Health and Disease Cohort. Levels of C-peptide, glycated haemoglobin (HbA1c), leptin and adiponectin were mea
Nitric oxide (NO)‐independent pathways contributing to acetylcholine (ACh)‐induced relaxation were examined in the rat isolated hepatic artery and aorta at low and high levels of precontraction induced by phenylephrine (PhE). In the hepatic artery, the ACh‐induced relaxation was unaffected by the NO synthase inhibitors Nw‐nitro‐L‐arginine (L‐NOARG, 0.3 mM) and Nω‐nitro‐L‐arginine methyl ester (0.1
Lung cancer and chronic lung diseases impose major disease burdens worldwide and are caused by inhaled noxious agents including tobacco smoke. The cellular origins of environmental-induced lung tumors and of the dysfunctional airway and alveolar epithelial turnover observed with chronic lung diseases are unknown. To address this, we combined mouse models of genetic labeling and ablation of airway
Dispersal distance, measured as the number of territories between place of birth and place of first breeding, was analysed within and between sexes in juvenile marsh tits in relation to factors potentially caiusing variation in dispersal pattern. Dispersal distance of males was positively influenced by both population density and hatching date. In females, dispersal distance were positively relate
This paper uses the three spatial design workshops D-Thinking Urban Strategy; Re-Ts >> Space(s) Innovation, and ZHUuGROUND 14 as the intellectual framework to evaluate experimentation as a pedagogical model in current interdisciplinary design education. The three workshops were conducted by the independent teaching and research organization, the Research Institute for Experimental Architecture (RI
The development of materials that are non-magnetic in the bulk but exhibit two-dimensional (2D) magnetism at the surface is at the core of spintronics applications. Here, we present the valence-fluctuating material EuIr2Si2, where in contrast to its non-magnetic bulk, the Si-terminated surface reveals controllable 2D ferromagnetism. Close to the surface the Eu ions prefer a magnetic divalent confi
The X-linked DDX3X gene encodes an ATP-dependent DEAD-box RNA helicase frequently altered in various human cancers, including melanomas. Despite its important roles in translation and splicing, how DDX3X dysfunction specifically rewires gene expression in melanoma remains completely unknown. Here, we uncover a DDX3X-driven post-transcriptional program that dictates melanoma phenotype and poor dise
Incentive alignment is discussed as one of the key factors for successful implementation of supply chain management. However, there is a lack of empirical research regarding implementation as well as evaluation of the effects of alignment mechanisms in practice. The purpose of this study is therefore to explore and describe the current practice and to identify gaps of Supply chain incentive alignm
This paper elucidates the increased need of correct calculations of thermal bridges for low/near zero energy buildings. The variability of the results from calculations of transmission losses for a building can be large if the calculation method within EN ISO 13789:2007 is not fully understood. A survey has been carried out which shows that there are no consensus in Sweden regarding how to define
