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Popular Abstract in Swedish Hemolytiskt uremiskt syndrom (HUS) och trombotiskt trombocytopen purpura (TTP) är allvarliga sjukdomar hos barn och vuxna. HUS kännetecknas av mikroangiopatisk hemolytisk anemi (blodbrist med nedbrytning av röda blodkroppar), trombocytopeni (låga blodplättar) och akut njursvikt. Det är den vanligaste orsaken till akut njursvikt hos barn. Typisk HUS utlöses av tarminfektThis study investigated the pathogenesis of hemolytic uremic syndrome (HUS) and thrombotic thrombocytopenic purpura (TTP). (1) The relative roles of lipopolysaccharide and Shiga-like toxin-2 were studied in a mouse model of Escherichia coli O157:H7 infection. Both factors were found to be important for the virulence of the strain and contributed in an additive manner. The mouse model mimicked cert

Anaerobic digestion is a microbially mediated process occurring in nature in the absence of oxygen and other non-carbonaceous electron acceptors. The majority of the carbon of the organic matter degraded in the process is transformed into carbon dioxide and methane. Most of the energy potential of the degraded material is conserved in the methane, thus providing a renewable energy carrier, which c

The recent explosion in size and complexity of datasets and the increased availability of computational resources has led us to what is sometimes called the big data era. In many big data fields, mathematical optimization has over the last decade emerged as a vital tool in extracting information from the data sets and creating predictors for unseen data. The large dimension of these data sets and

Rotational singularities inherent to three different geometric controllers on SE (3) are studied. A new singularity-free method of incrementally generating a reference rotation is proposed, removing a class of singularities without affecting proven stability properties of the closed-loop systems. If satisfying a bound on attitude rate and maximum loop rate in the reference generation, the proposed

We consider temperature stabilization of the phase-reference line at the European Spallation Source, a facility for neutron spallation currently under construction. Based on extensive modeling of the heat dynamics, a prototype model-based control system with associated hardware architecture is developed and experimentally evaluated on a small-scale setup. The results indicate that temperature stab

This study examines cross-linguistic influence (CLI) in adult Italian-German bilinguals based on the production of gemination, a phenomenon that exists in Italian but not in German. We analyzed the spontaneous Italian speech of two groups of Italian-German bilinguals (heritage speakers of Italian and Italian-dominant bilinguals) and a monolingual Italian control group. The results show that the ge

Nowadays, we live in a society with billions of devices that are interconnected and interact together to improve the quality of our lives. The management and processing of information and knowledge have by now become our main resources, and the fundamental factors of economic and social development, and it is achieved through Big Data Frameworks (BDFs). The amount of such data is becoming larger e

Numerical finite element results on the mechanical behaviour of finger-joints for laminated timber products are presented. Simulations are based on a nonlinear fracture mechanics description of the bondlines in the finger-joints. It is shown that, for a commonly used resorcinol–phenol adhesive, there is potential of increasing substantially the finger-joint strength by increasing the fracture ener

Attention is drawn to some of the limitations of conventional plume theory, some differences between axi-symmetric and line plumes, and some rationalisation which is possible in correlating data for the flow from wide vertical openings. The paper is more a summary and a series of notes than a lengthy exercise in the subject.

The kinetic properties of dUTPase from equine infectious anemia virus (EIAV) were investigated. KM (1.1 [plusmn] 0.1 [mu ]M) and kcat (25 s[minus ]1) were found to be independent of pH in the neutral pH range. Above pH 8.0, KM increases slightly. Below pH 6.0, the enzyme is rapidly deactivated. Detergent was found to enhance activity, leaving KM and kcat unaffected. Compared to the Escherichia col

We have fit synthetic visibilities from three-dimensional ((COBOLD)-B-5+PHOENIX) and one-dimensional (PHOENIX, ATLAS 12) model stellar atmospheres of Procyon (F5 IV) to high-precision interferometric data from the VLT Interferometer (K band) and from the Mark III interferometer (500 and 800 nm). These data sets provide a test of theoretical wavelength-dependent limb-darkening predictions. The work

Autoimmune type 1 diabetes is strongly associated with a number of immune abnormalities that manifest themselves before and at the time of clinical diagnosis. The clinical onset is associated with a major loss of the pancreatic islet beta cells. Insulin treatment is the only treatment option since numerous trials with agents that suppress or modulate immune function have failed to preserve beta ce

High-spin states in the proton-rich nucleus V-45 have been identified for the first time. A comprehensive gamma-ray decay scheme has been established following an experiment performed at the Vivitron accelerator at IReS Strasbourg by using the Euroball gamma-ray detector array coupled to the Neutron Wall and Euclides detector arrays. The natural (negative-) parity scheme is identified up to the f(

We have simulated the 10-state 2d Potts model with the Metropolis and Swendsen-Wang algorithms, in order to compare their performances near a first-order phase transition. We show that a simple Markov model relates the frequencies of the flips between coexisting phases and the auto-correlation times. It leads to a coherent description of the dynamics. The ratio of the algorithm efficiencies has li

The decay from the 23+ state at about 2-MeV excitation in the nuclei Ba140, Ce142, and Nd144, with 84 neutrons, is shown to be consistent with its identification as the lowest state of mixed symmetry in the U(5) limit of the neutron-proton version of the interacting-boson model.

Objectives: To investigate the preoperative prognostic value of molecular subtypes in relation to clinical information, histopathological findings, and molecular markers for patients with bladder cancer treated with radical cystectomy. Patients and methods: After standard preoperative staging, a population-based cohort of 519 patients under