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Aim: It has been suggested that experiencing serious life events may promote Type 1 diabetes in children. Studies in adults are lacking, as are studies on the interaction of life events with genetic factors. We aimed to investigate life events and the risk of latent autoimmune diabetes in adults (LADA) and Type 2 diabetes while taking into account HLA genotype. Methods: Analysis was based on 425 i
Introduction This study follows cadmium and lead concentrations in blood in the adult population in northern Sweden over 24 years. Material and methods Concentrations of lead and cadmium were measured in single whole blood samples (B-Pb and B-Cd) from 619 men and 926 women participating in the Northern Sweden WHO MONICA Study on one occasion 1990–2014. Associations with smoking and dietary factors
Computational approaches are essential to study the effects of inborn and somatic variations. Results from such studies contribute to better diagnosis and therapies. Primary immunodeficiencies (PIDs) are rare inborn defects of key immune response genes. Somatic variations are main drivers of most cancers. Large and diverse data on PID genes and proteins can enable systems biology studies on their
Background: The stresses of modern work life necessitate effective copingstrategies that are accessible and affordable to the general public. Yogahas been found to reduce stress in clinical samples, but studies areneeded to examine standard gym yoga classes among functionalindividuals.Objectives: This study investigated the effects of 8- and 16-week gymyoga on stress and psychological health.Desig
Operationalizing a Global Carbon Observing and Analysis System (www.geocarbon.net) would provide a sound basis for monitoring actual carbon fluxes and thus getting quantities right when pricing carbon - be it in a cap-and-trade scheme or under a tax regime. However, such monitoring systems are expensive and-especially in times of economic weakness-budgets for science and environmental policy are u
The Amazon rainforest is disproportionately important for global carbon storage and biodiversity. The system couples the atmosphere and land, with moist forest that depends on convection to sustain gross primary productivity and growth. Earth system models that estimate future climate and vegetation show little agreement in Amazon simulations. Here we show that biases in internally generated clima
Cellulose is the most abundant polymer and a very important renewable resource. Since cellulose cannot be shaped by melting, a major route for its use for novel materials, new chemical compounds and renewable energy must go via the solution state. Investigations during several decades have led to the identification of several solvents of notably different character. The mechanisms of dissolution i
Purpose: To examine test–retest reliability and construct validity of the Scandinavian version of the caregiver priorities and child health index of life with disabilities (CPCHILD) questionnaire for children with cerebral palsy (CP). Methods: Families were recruited in Sweden and Norway and stratified according to the gross motor function classification system levels I–V for children born 2000–20
Time-dependent distribution of extracellular proteins (albumin, fibrinogen, fibronectin, collagen-I and IgG) in the interface zone between implant and soft tissue has been investigated utilizing a recently developed method. Commercially pure (c.p.) titanium and polytetrafluoroethylene (PTFE) implants were inserted in the abdominal wall of rats for 1, 6 and 12 weeks followed by a mild fixation, cry
An improvement in our process-based understanding of carbon (C) exchange in the Arctic and its climate sensitivity is critically needed for understanding the response of tundra ecosystems to a changing climate. In this context, we analysed the net ecosystem exchange (NEE) of CO2 in West Greenland tundra (64°N) across eight snow-free periods in 8 consecutive years, and characterized the key process
The savanna complex is a highly diverse global biome that occurs within the seasonally dry tropical to sub-tropical equatorial latitudes and are structurally and functionally distinct from grasslands and forests. Savannas are open-canopy environments that encompass a broad demographic continuum, often characterised by a changing dominance between C3-tree and C4-grass vegetation, where frequent env
Land management for carbon storage is discussed as being indispensable for climate change mitigation because of its large potential to remove carbon dioxide from the atmosphere, and to avoid further emissions from deforestation. However, the acceptance and feasibility of land-based mitigation projects depends on potential side effects on other important ecosystem functions and their services. Here
We present two novel earth observation products derived from the BESD and EMMA XCO2 products which were respectively retrieved from SCIAMACHY and GOSAT observations within the GreenHouse Gas project of ESA's Climate Change Initiative (GHG-CCI). These products are inferred by a Carbon Cycle Data Assimilation System (CCDAS) and consist of net and gross biosphere-atmosphere fluxes of carbon dioxide o
The MAX IV 3 GeV storage ring is presently being commissioned and crucial parameters such as machine functions, emittance, and stored current have either already been reached or are approaching their design specifications. Once the baseline performance has been achieved, a campaign will be launched to further improve the brightness and coherence of this storage ring for typical X-ray users. During
The effects of the position of a bluff-body on diffusion flame structures and flame instability characteristics were investigated both experimentally and numerically. The flame pattern diagram and the stability limits of the methane-air diffusion flame were investigated to evaluate the effects caused by the alternation of the position of a bluff-body. A disk-shape bluff-body was mounted 10 mm abov
To study global nitrogen (N) leaching from natural ecosystems under changing N deposition, climate, and atmospheric CO2, we performed a factorial model experiment for the period 1901-2006 with the N-enabled global terrestrial ecosystem model LPJ-GUESS (Lund-Potsdam-Jena General Ecosystem Simulator). In eight global simulations, we used either the true transient time series of N deposition, climate
