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Chronic breathlessness is a dominating symptom that restricts daily life for many people with cardiorespiratory disease [1]. Different dimensions of the symptom, such as the intensity, sensory qualities and emotional responses, can be assessed using the instruments Dyspnea-12 (D-12) [2] and the Multidimensional Dyspnea Profile (MDP) [3], which share similarities in the underlying constructs of wha

Even though floral scent is of major importance for pollinator attraction, it is less investigated than other floral traits. Previous studies suggest the importance of joint exploration of olfactory and visual floral cues to understand plant–pollinator interactions. We investigated flower scents in Collinsia heterophylla, a bee-pollinated, annual herb a with mixed-mating system combining self- and

Background Exertional breathlessness is a limiting symptom that often coexists with anxiety and depression. We tested the hypothesis that anxiety and depression negatively impact exertional breathlessness in daily life and during standardised cardiopulmonary exercise testing (CPET). Methods Analysis of people aged ⩾40 years undergoing incremental cycle CPET. Exertional breathlessness in daily life

What are the main challenges for fossil-free agriculture and food systems, according to Swedish farmers? And what do farmers think fossil-free farms should look like, and how should they function? What actions are needed from different actors to achieve these visions by 2050? These questions were discussed during a lunch-to-lunch workshop in Eskilstuna, 13-14 November 2025. The purpose of the work

Objective This study aims to investigate whether oral fluoroquinolone use is associated with an increased risk of aortic and mitral valve regurgitation. Design A nationwide cohort study based on linked healthcare register data encompassing patient characteristics, prescription data and cases of aortic and mitral valve regurgitation. Setting Sweden, 2006–2018. Participants Study participants were a

This paper studies cone-preserving linear discrete-time switched systems whose switching is governed by an automaton. For this general system class, we present performance analysis conditions for a broadly usable performance measure. In doing so, we generalize several known results for performance and stability analysis for switched and positive switched systems, providing a unifying perspective.

Emerging evidence suggests that bidirectional lung–kidney crosstalk may influence outcomes, but this has not been systematically evaluated in unselected emergency department populations. We therefore examined the association between peripheral oxygen saturation (SpO₂), estimated glomerular filtration rate (eGFR), and 30‑day mortality, and tested whether the prognostic association of oxygenation wi

Climate change is expected to alter the frequency and intensity of soil drying-rewetting (D/RW) and freezing-thawing (F/TW) events, with consequences for the activities of microorganisms. Although both D/RW and F/TW events cause respiration pulses from soil to the atmosphere, it remains unknown whether the underlying microbial control is similar. Recent work has revealed that soil microbial respon

Hematopoietic stem cells (HSCs) are rare cells on top of the differentiation hierarchy of hematopoiesis. HSCs are unique in their combined capacity to differentiate into all mature blood lineages and self-renew to maintain the HSC pool. Based on classical models of hematopoiesis in mouse, the self-renewal potential of HSCs is gradually and step-wise lost during the transition from long term (LT)-H

Large igneous provinces (LIPs) and especially their dyke swarms are pivotal to reconstruction of ancient supercontinents. The Dharwar craton of southern Peninsular India represents a substantial portion of Archean crust and has been considered to be a principal constituent of Superia, Sclavia, Nuna/Columbia and Rodinia supercontinents. The craton is intruded by numerous regional-scale mafic dyke s

Background: Little is known about the long-term effectiveness of behavioural therapy for tics. We aimed to assess the long-term clinical and cost-effectiveness of online therapist-supported exposure and response prevention (ERP) therapy for tics 12 and 18 months after treatment initiation. Methods: ORBIT (online remote behavioural intervention for tics) was a two-arm (1:1 ratio), superiority, sing

We performed a comprehensive study of the charge carrier diffusion in the CsMAFA perovskite, one of the state-of-the-art perovskites for photovoltaic applications, starting from the diffusion of hot carriers to the eventual trapping at the surfaces and grain boundaries. We discovered evidence of non-ambipolar diffusion by using ultrafast transient reflectance spectroscopy: by comparing the transie

Background: Renal cell carcinoma (RCC) is twice as common among men compared with women, and hormonal factors have been suggested to partially explain this difference. There is currently little evidence on the roles of reproductive and hormonal risk factors in RCC aetiology. Materials & Methods: We investigated associations of age at menarche and age at menopause, pregnancy-related factors, hy

Red blood cell (RBC) and iron status biomarkers are commonly used in clinical diagnostics. However, interpretations of infant test results are inherently challenging. Modern well-defined comparative data based on presumably healthy term-born infants have mainly been lacking and interpretations could be further complicated by interference from frequent infections. Moreover, the trends that follow w

Objectives: To study the risk of osteoporosis-related fractures in a community-based sample of men and women with rheumatoid arthritis (RA) overall, as well as early (< 1 year of disease duration, follow-up time maximum 10 years) and established (RA diagnosis since ≥ 5 years on July 1, 1997) RA, compared with the general population. To study potential risk factors for fractures in patients with RA

There is significant interest from the medical andneuroscience communities for studying the behavior of zebrafishlarvae, particularly in the context of drug testing. In this paper, wepropose a method for analyzing the behavior of zebrafish larvaein a high-throughput system using automatic image analysis.Specifically, algorithms for estimating the poses of the larvae invideo recordings are presente