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The European Association of Urology (EAU) 2021 prognostic model for non–muscle-invasive bladder cancer (NMIBC) is based on the World Health Organization (WHO) 1973 and/or WHO 2004/2022 grading systems for patients who did not receive bacillus Calmette-Guérin (BCG) instillations and is widely used to assess the risk of progression. The estimated risk of progression affects the type of adjuvant intr
Popular Abstract in Swedish Datorsimuleringar, konsten att modellera verkliga eller tänkta händelser med hjälp av en dator och ett lämpligt simuleringsprogram, har blivit ett dominerande verktyg inom tekniska och naturvetenskapliga områden, likväl inom akademiska och industriella tillämpningar. Trots att experimentella studier har ett vedertaget erkännande inom diverse forskningsstudier har den snThis thesis concerns the study of Fluid-Structure interaction phenomena among deforming and (non-deforming) vibrating objects under unsteady fluid fl ow exposures. This multi-physical phenomenon is widely encountered in real-life situations and therefore it is of significant importance to understand the underlying physics. The trend is that both industrial and research facilities aim for developi
This paper deals with the ethical debate concerning human stem cell research and the methods that are associated with it from a patent law perspective. It will focus on the patentability of human embryonic stem cells at the European Patent Office (EPO) and in Germany.
Abstract not available
Popular Abstract in Swedish Idag baserat på konceptet grön kemi - börjar man att utveckla nya miljövänliga processer i produktionen av kemikalier, genom att använda förnyelsebara råvaror och minska giftigt avfall. I denna avhandling används enzymer för att bilda kemikalier som en del i utvecklingen av nya miljöprocesser. Enzymer är proteiner som påskyndar (katalyserar) kemiska reaktioner för olikaThe constant need to develop environmental friendly processes using renewable raw materials and to reduce harmful waste production motivates the present investigation focusing on biocatalyst development for enzymatic synthesis, a biotechnological approach in the field of green chemistry. At first, structural functional experiments were made for a β-glucosidase from T. neapolitana (TnBgl3B). As a
Objective: The aim of this investigation was to study differences between male and female patients with stage T1 urinary bladder cancer (UBC) regarding intravesical instillation therapy, second resection and survival. Materials and methods: This study included all patients with non-metastatic primary T1 UBC reported to the Swedish National Register of Urinary Bladder Cancer (SNRUBC) from 1997 to 2
This doctoral dissertation investigates how Plato elaborates and incorporates the works of the poets in the preludes to the laws. It is argued that the poetic style of the preludes represents a key element for the Athenian’s purpose of persuading the citizens of Magnesia to spontaneously abide to the new legislation that is being laid out.The analysis is divided in four chapters. Chapter 1 discuss
Abstract: A search is performed for the production of high-mass resonances decaying into a photon and a jet in 3.2 fb−1of proton-proton collisions at a centre-of-mass energy of (Formula presented.) TeV collected by the ATLAS detector at the Large Hadron Collider. Selected events have an isolated photon and a jet, each with transverse momentum above 150 GeV. No significant deviation of the γ+jet in
Optimisation of radiological protection for operators working with fluoroscopically guided procedures has to be performed during the procedure, under varying and difficult conditions. The aim of the present study was to evaluate the impact of a system for real-time visualisation of radiation dose rate on optimisation of occupational radiological protection in fluoroscopically guided procedures. In
Three-dimensional (3D) solar maps based on Radiance simulations are presented for a future city district in southern Norway. The surface mapping method provides the commercial developer with a practical tool to evaluate the potential for building integrated photovoltaics (BIPV). The solar maps identify the optimum roof and facade areas available for solar energy utilization. The importance of BIPV
Groundwater quality and quantity are two major challenges in arid and semi-arid regions, due to their critical roles in sustainable agricultural development. Irrigated lands are spread all over Urmia Lake's surrounding plains in Iran. Due to the risk of saltwater intrusion as a result of over-exploitation from groundwater resources, it is important to monitor the groundwater quality and quantity t
A search is conducted for a beyond-the-Standard-Model boson using events where a Higgs boson with mass 125 GeV decays to four leptons (ℓ = e or μ). This decay is presumed to occur via an intermediate state which contains one or two on-shell, promptly decaying bosons: H → ZX/XX → 4ℓ, where X is a new vector boson Zd or pseudoscalar a with mass between 1 and 60 GeV. The search uses pp collision data
We created a system to simulate the heart allocation process in a transplant queue, using a discrete event model and a neural network algorithm, which we named the Lund Deep Learning Transplant Algorithm (LuDeLTA). LuDeLTA is utilized to predict the survival of the patients both in the queue and after transplant. We tried four different allocation policies: wait time, clinical rules and allocating
We prospectively evaluated a combination of fungal biomarkers in adult haematology patients with focus on their clinical utility at different time points during the course of infection. In total, 135 patients were monitored once to twice weekly for serum (1-3)-ß-d-glucan (BG), galactomannan (GM), bis-methyl-gliotoxin and urinary d-arabinitol/l-arabinitol ratio. In all, 13 cases with proven or prob
Changes to the smallest structures of the distal lung are often the first sign of severe respiratory disease, but to date methods to detect and quantify these changes are limited. Chronic obstructive pulmonary disease (COPD) is currently estimated to be the third most common cause of death worldwide, but is to a large extent under-diagnosed, especially at early stages. This thesis explores a new m
