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This study investigates the mechanisms of (de)coding modality, focusing on the interpretation of utterances containing the modals must, may, måste, and kan. The main research question posed in this study is what enables the interlocutors to interpret modal expressions so that communicative goals are achieved. To answer this general question, Coates's (1983) study on modal contexts is initially rep
In vitro reassembled aggregates of cartilage proteoglycan (aggrecan) were studied by glycerol spraying/rotary shadowing electron microscopy and compared to the corresponding native (i.e. never dissociated) structures. In both cases a tightly packed central filament structure was observed consisting of the hyaluronate binding region (HABR) of the proteoglycan, link protein (LP) and hyaluronate (HA)
A new approach to the design of time windows is presented for detection of transient-evoked otoacoustic emissions (TEOAE). The windows are designed with reference to a minimum mean square error criterion involving the correlation properties of the ensemble of responses. Latency information is introduced in the detection process by windowing at different scales that result from wavelet decompositio
Abstract Multimodal learning materials are frequently met in education assuming enhanced learning outcomes. This study examined whether contrasts in such materials are likely to support reading comprehension for all readers. Young adults (n=46) met either text-only or text+picture material. Participants (19 with low phonological awareness [PA] and 27 controls with high PA) thereafter answered open
OBJECTIVE-Although insulin resistance (IR) may underlie associations between depressive symptoms and diabetes, previous findings have been contradictory. We examined whether depressive symptoms associate with IR and insulin secretion, and, additionally, whether antidepressant medication use may modulate such associations. RESEARCH DESIGN AND METHODS-A total of 4,419 individuals underwent an oral g
My PhD submission is made up of a constellation of three elements that form a body of textual material / theory and practice event / exhibition. (1) A dimension of critical writing or dissertation that has two parts: (a) Retrospective / Prospective: Activating the Archive, September 1, 2010, and (b) an accretion of further analysis, Archive, Archived, Archiving, September 1, 2011. (2) A testin
High-resolution palaeoecological proxies of pollen, macrofossils and diatoms from an isolation lake provide a long-term record of the Holocene landscape history and shoreline displacement on the Biskopsmala Peninsula in central Blekinge, SE Sweden. During the Preboreal/Boreal transition, the peninsula was sparsely vegetated by woodlands, along with lateglacial dwarf shrub/steppe communities. The l
Results of the Jefferson Lab Hall A quasielastic 3He(e,ep)pn measurements are presented. These measurements were performed at fixed transferred momentum and energy, q=1502 MeV/c and =840 MeV, respectively, for missing momenta pm up to 1 GeV/c and missing energies in the continuum region, up to pion threshold; this kinematic coverage is much more extensive than that of any previous experiment. The
Europe has positioned itself as a front runner for climate mitigation policy globally. However, to reach climate mitigation targets that go far beyond Kyoto commitments, climate policy must become more integrated with sectoral policies such as energy, transport and agriculture. To achieve such policy integration, policy refraining and dilemma sharing among sectoral actors are important mechanisms.
The interactions, in aqueous media, between a pyrene-labelled polyelectrolyte poly(acrylic acid) (PAAMePy) with two different degrees of labelling and beta- and gamma-cyclodextrins (beta- and gamma-CD) were studied using absorption and fluorescence (steady-state and time-resolved) techniques. In addition to qualitative and quantitative parameters obtained from absorption and steady-state fluoresce
Type 2 diabetic patients are at increased risk to develop atherosclerotic vascular disease. These patients are often treated with sulphonylurea derivatives, and it has been suggested that this treatment might contribute to the increased atherosclerotic process. The aim of the present study was therefore to investigate whether tolbutamide influences lipid metabolism in such a way that the atheroscl
The influence of sodium dodecyl sulfate (SDS) on the interfacial behavior of two amphiphilic polyelectrolytes, which are copolymers of the cationic monomers triethyl(vinylbenzyl)ammonium chloride and dimethyldodecyl(vinylbenzyl)ammonium chloride, at the silica-aqueous interface was studied. The fraction of amphiphilic monomers was varied, where ODT, 40DT, and 80DT contained 0, 40, and 80 mol % mon
In a simulation model we investigated how much of the initial genetic variation that is retained in a population after a dominant mutation has brought apomixis to fixation in it. A marker allele associated with the apomixis mutation is generally retained after the fixation of apomixis, particularly if the two alleles are closely linked. The spread of asexuality, however, normally leads to almost n
Morphogenesis of the Drosophila melanogaster embryo is associated with a dynamic reorganization of the actin cytoskeleton that is mediated by small GTPases of the Rho family. Often, Rho1 controls different aspects of cytoskeletal function in parallel, requiring a complex level of regulation. We show that the guanine triphosphate (GTP) exchange factor DRhoGEF2 is apically localized in epithelial ce
Retinitis pigmentosa is a blinding disease in which unknown mechanisms cause the degeneration of retinal photoreceptors. The retinal degeneration (rd1) mouse is a relevant model for this condition, since it carries a mutation also found in some forms of retinitis pigmentosa. To understand the degenerative process in the rd1 mouse, we must identify the survival and apoptosis-related signaling pathw
Recombinant adeno-associated viral (rAAV) vector-induced neuropeptide Y (NPY) overexpression in the hippocampus exerts powerful antiepileptic and antiepileptogenic effects in rats. Such gene therapy approach could be a valuable alternative for developing new antiepileptic treatment strategies. Future clinical progress, however, requires more detailed evaluation of possible side effects of this tre
This paper provides an empirical analysis of market behaviour under ‘Tradable White Certificate’ (TWC) schemes. It focuses on the entire set of ‘flexibilities’ granted to obliged parties to meet a mandatory energy-saving target cost-effectively, i.e. range eligible measures, eligible end-use sectors, banking provision, market engagement of non-obliged parties, and trading as such. We found that ma
We consider the following clustering problems: given an undirected graph, partition its vertices into disjoint clusters such that each cluster forms a clique and the number of edges within the clusters is maximized (Max-ECP), or the number of edges between clusters is minimized (Min-ECP). These problems arise naturally in the DNA clone classification. We investigate the hardness of finding such pa
