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Associations of Macronutrients Intake With MRI-determined Hepatic Fat Content, Hepatic Fibroinflammation, and NAFLD

CONTEXT: A healthy lifestyle is the cornerstone of management in nonalcoholic fatty liver disease (NAFLD). However, the associations between dietary macronutrient composition and different aspects of NAFLD pathology are unclear and dietary recommendations for NAFLD are lacking.OBJECTIVE: This work aimed to evaluate the associations of dietary macronutrient composition with hepatic steatosis, hepat

Distributed attitude synchronization control of multi-agent systems with directed topologies

In the present paper we consider the problem of attitude synchronization for a system of rigid body agents. We provide distributed kinematic control laws for two different synchronization problems. In the two problems the objective is the same, i.e., to synchronize the orientations of the agents, but what is assumed to be measurable by the agents differs. In problem 1 the agents measure their own

Prospective teachers’ conceptions of analysis and beliefs about their impending profession

A group of pre-service teachers were studied from two social practices, as teachers and as students. Their perceptions of mathematics concepts and beliefs about the mathematics teacher role were studied through questionnaires, interviews and classroom observations. Three students were selected as cases in this paper where their links between the concepts limits, derivatives, integrals and continui

Corrosion Rates by Immersion and Calorimetry on the Example of Extruded Mg10Gd(1Nd)1La

This study is a follow-up investigation of the influence of the alloying elements Nd and La on the corrosionCorrosionby immersionImmersion of an extruded and heat-treated Mg10Gd. The previous study made clear that the age-hardened condition has the lowest corrosion rateCorrosion Rate but high pitting corrosionPitting corrosion susceptibility. The extruded Mg10Gd(1Nd)1La shows the lowest pitting fa

The right to the unhealthy deprived city : An exploration into the impacts of state-led redevelopment projects on the determinants of mental health

Research shows mental health is impacted by poor-quality physical and social-environmental conditions. Subsequently state-led redevelopment/regeneration schemes focus on improving the physical environment, to provide better social-environmental conditions, addressing spatial and socioeconomic inequities thus improving residents' health. However, recent research suggests that redevelopment/regenera

LNLS vacuum system commissioning

The Brazilian National Synchrotron Light Laboratory, LNLS, operates a synchrotron light source consisting of a 1.37 GeV electron storage ring and a 120 MeV injector. A summary of the commissioning and operation performance of the vacuum system for the linear accelerator (LINAC), transport line, RF system and storage ring is presented. The performance of the subsystems is described including the ph

Climate change adaptation in the built environment : Transdisciplinary and Innovative Learning

Global climate change is one of the greatest environmental threats facing humanity and it is affecting every country on every continent. Recent evidence confirms a close liaison between climate change induced hazards and the built environment, as the built environment demonstrates a high fragility and vulnerability to hazardous situations. The impact of climate change is particularly pertinent to

Digital Competencies, Disaster Risk Reduction, and Education : An Introduction to the Digital Competency Framework to Develop Digital Pedagogical Competencies of Educators in Disaster Risk Reduction.

The COVID-19 pandemic was a novel biological hazard that emerged in 2019 and significantly impacted various sectors of society. While sectors such as the economy and health were severely affected, the education sector was no stranger to the grave impact of the pandemic. While the pandemic called for regulations such as lockdowns and social distancing, the education sector was required to shift the

Decipherment of Historical Manuscripts with Unknown or Rare Writings : The DESCRYPT Project

We present a newly funded research program, DESCRYPT, aimed at deciphering and analyzing historical texts with rare or unknown scripts. The project leverages advancements in computational linguistics, artificial intelligence (AI), and image processing, alongside traditional philological methods, to develop innovative tools for transcription, recognition, and interpretation of historical writings w

Risk Factors for Complicated Mohs Surgery in the South Sweden Mohs Cohort

Background: Mohs micrographic surgery (MMS) is a precise, tissue-sparing surgical technique that offers superior cure rates compared to traditional surgical excision. However, the degree of difficulty of MMS depends on many variables, and consequently, the number of surgical stages required for each case is quite unpredictable.Objectives: To identify risk factors for complicated MMS, defined as MM

Frequency domain sensitivity shaping using overparametrized controllers

A frequency domain, weighted least squares, sensitivity function shaping procedure is presented. Pole placement is used as the basic servo design procedure. Controller overparametrization gives the degree of freedom for shaping the sensitivity function. A benchmark design example shows the capabilities of the method. The computation is simple making the design suitable for adaptive control.

Calcium, Its Regulatory Hormones, and Their Causal Role on Blood Pressure : A Two-Sample Mendelian Randomization Study

CONTEXT: Vitamin D (Vit-D), parathyroid hormone (PTH), and fibroblast growth factor 23 (FGF23) are the major calciotropic hormones involved in the regulation of blood calcium levels from the intestine, kidney, and bone through a tight endocrine feedback loop system. Altered levels of calcium itself or through the effect of its regulatory hormones could affect blood pressure (BP), but the exact mec

MSCs interaction with the host lung microenvironment : An overlooked aspect?

Mesenchymal stromal cells (MSCs) were identified more than 50 years ago, and research advances have promoted the translation of pre-clinical studies into clinical settings in several diseases. However, we are only starting to uncover the local factors that regulate cell phenotype, cell function, and cell viability across tissues following administration in different diseases. Advances in pre-clini

Deep Neural Network for the Prediction of KRAS Genotype in Rectal Cancer

BACKGROUND: KRAS mutation can alter the treatment plan after resection of colorectal cancer. Despite its importance, the KRAS status of several patients remains unchecked because of the high cost and limited resources. This study developed a deep neural network (DNN) to predict the KRAS genotype using hematoxylin and eosin (H&E)-stained histopathological images. STUDY DESIGN: Three DNNs were c

Sexual Violence in Criminal Law : Presumptions, Principles and Premises in Relation to the Crime of Negligent Rape

In this chapter I analyse the recent criminalization of negligent rape in Sweden, introduced in 2018. My aim is to contribute to the discussion of criminalization as it relates to violence against women, while taking a broad view of criminalization that includes not only criminalization per se but also the application of law. My analysis of the application of the crime of negligent rape, from the

Combined effect of factor V Leiden and prothrombin 20210A on the risk of venous thromboembolism : Pooled analysis of 8 case-control studies including 2310 cases and 3204 controls

Factor V Leiden and factor II G20210A mutations are two frequent genetic risk factors involved in venous thromboembolism (VTE). The goal of this pooled analysis of 8 case-control studies, comprising a total of 2310 cases and 3204 controls, was to precisely estimate the risk of VTE in patients bearing both mutations (double heterozygotes). Odds ratios for VTE were 4.9 (95% CI; 4.1-5.9) for the fact

Supply chain competence: A literature study

Purpose Competence is a prerequisite to achieve a well-functioning and competitive supply chain (SC). The purpose of this review is to present an integrated view of the published literature on all the aspects and facets of supply chain competence, and to present a framework for classification and analysis to facilitate further study, practice and research. Design/methodology/approach A structured