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Isometric multi-shape matching

Finding correspondences between shapes is a fundamental problem in computer vision and graphics, which is relevant for many applications, including 3D reconstruction, object tracking, and style transfer. The vast majority of correspondence methods aim to find a solution between pairs of shapes, even if multiple instances of the same class are available. While isometries are often studied in shape

Linear shape deformation models with local support using graph-based structured matrix factorisation

Representing 3D shape deformations by high-dimensional linear models has many applications in computer vision and medical imaging. Commonly, using Principal Components Analysis a low-dimensional subspace of the high-dimensional shape space is determined. However, the resulting factors (the most dominant eigenvectors of the covariance matrix) have global support, i.e. changing the coefficient of a

Distinct microRNA Signature and Suppression of ZFP36L1 Define ASCL1-Positive Lung Adenocarcinoma

Achaete-scute family bHLH transcription factor 1 (ASCL1) is a master transcription factor involved in neuroendocrine differentiation. ASCL1 is expressed in approximately 10% of lung adenocarcinomas (LUAD) and exerts tumor-promoting effects. Here, we explored miRNA profiles in ASCL1-positive LUADs and identified several miRNAs closely associated with ASCL1 expression, including miR-375, miR-95–3p/m

How do scientists develop and use scientific software?

New knowledge in science and engineering relies increasingly on results produced by scientific software. Therefore, knowing how scientists develop and use software in their research is critical to assessing the necessity for improving current development practices and to making decisions about the future allocation of resources. To that end, this paper presents the results of a survey conducted on

Long-term evolution of three-planet systems to the post-main sequence and beyond

We study the stability of systems of three giant planets orbiting 3-8 M☉ stars at orbital distances of >10 au as the host star ages through the main sequence (MS) and well into the white dwarf (WD) stage. Systems are stable on the MS if the planets are separated by more than ~9 Hill radii. Most systems surviving the MS will remain stable until the WD phase, although planets scattered on to small p

Mach Number on Outlet Plane of a Straight Micro-Tube

The Mach number and pressure on the outlet plane of a straight micro-tube were investigated numerically for both laminar and turbulent flow cases. The numerical methodology is based on the Arbitrary-Lagrangian-Eulerian (ALE) method. The LB1 turbulence model was used for the turbulent flow case. The compressible momentum and energy equations with the assumption of the ideal gas were solved. The com

Update of the Finnish-Swedish beam line I411 at MAX-lab: Simulations of expected performance

In the modified SX-700 monochromator installed at beam line I411, the focusing before the exit slit is achieved by a plane elliptical mirror. Like in the original SX-700 design, the resolution is mainly limited by the slope errors of the focusing mirror. A simple method to improve the resolution is to replace the focusing mirror by one with smaller slope errors. The effects of replacing the refocu

Rhythmic contrast between Swedish and Albanian as an explanation for L2-speech?

Based on observations of the rhythmic structure of L2-speech produced by L1-speakers of Albanian – which suggest the occurrence of transfer – a study is presented here that compares durational aspects between the two languages. In order to do this, speech read by Swedish and Albanian L1-speakers was recorded and investigated, and normalized durational factors were analysed. The results, however, d

Bridging the State and Society: Case Study of Mahalla Institutions in Uzbekistan

Abstract in UndeterminedUzbekistan, after gaining independence from the Soviet Union in 1991, had publicly declared that it would adhere to democratic governance principles in designing and implementing its public administration policies. As a newly-independent state with democracy claims, Uzbekistan had tried to establish new democratic institutions with an effort to capture international communi

Immunohistochemistry in the differential diagnostics of primary lung cancer: an investigation within the southern Swedish lung cancer study.

Objectives: To assess immunohistochemical (IHC) stains differentially expressed between different types of lung cancer. Methods: We evaluated 16 different IHC stains in 209 prospectively included, surgically treated primary lung cancers, including 121 adenocarcinomas, 65 squamous cell carcinomas, 15 large-cell carcinomas, 5 adenosquamous carcinomas, 2 sarcomatoid carcinomas, and 1 small-cell carci

Decreased levels of autoantibodies against apolipoprotein B-100 antigens are associated with cardiovascular disease in systemic lupus erythematosus.

Increased production of autoantibodies is a characteristic feature of systemic lupus erythematosus (SLE) and there is evidence that several of these autoantibodies may contribute to the increased cardiovascular disease (CVD) in SLE. Autoantibodies against the apolipoprotein (apo) B-100 peptides p45 and p210 have been associated with a lower CVD risk in non-SLE cohorts. The aim of the present study

Radiative parameters of Nb i excited states

Radiative lifetimes of 17 excited levels of Nb i, in the energy range 27 400-47 700 cm-1 (5p y 6D degrees(9/2), 5p x 6D degrees(7/2), 5p w 4G degrees(7/2,9/2,11/2), 5s5p v 4D degrees(1/2,3/2,5/2,7/2), 5s6p n 4D degrees(1/2,3/2,5/2,7/2), 5s6p o 4F degrees(3/2,5/2,7/2,9/2)), have been measured. For 15 of these levels, the lifetimes are obtained for the first time. The lifetimes were measured using t

ZnT8 autoantibody epitope specificity and affinity examined with recombinant ZnT8 variant proteins in specific ZnT8R and ZnT8W autoantibody positive type 1 diabetes patients.

Variant specific zinc transporter 8 autoantibodies (ZnT8A) against either arginine (R) or tryptophan (W) at amino acid (aa) position 325 of the zinc transporter 8 (ZnT8) has been identified in T1D patients. Reciprocal cross-over tests revealed differences in half-maximal binding to indicate variable affinity of patient ZnT8 autoantibodies. Insufficient recombinant ZnT8 variant proteins have preclu

The added value of a mobile application of Community Case Management on referral, re-consultation and hospitalization rates of children aged under 5 years in two districts in Northern Malawi : Study protocol for a pragmatic, stepped-wedge cluster-randomized controlled trial

Background: There is evidence to suggest that frontline community health workers in Malawi are under-referring children to higher-level facilities. Integrating a digitized version of paper-based methods of Community Case Management (CCM) could strengthen delivery, increasing urgent referral rates and preventing unnecessary re-consultations and hospital admissions. This trial aims to evaluate the a