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Following systemic injection, hematoporphyrin derivative (HPD) is known to be selectively retained in malignant tissue. This property can be used in a two-fold way: a) for localizing tumours by observing the characteristic dual-peaked laser-induced fluorescence from HPD, and b) for photodynamic therapy (HPD-PDT) using a localized HPD-assisted singlet oxygen release induced by irradiation of 630 nm

We study the stability of systems of three giant planets orbiting 3-8 M☉ stars at orbital distances of >10 au as the host star ages through the main sequence (MS) and well into the white dwarf (WD) stage. Systems are stable on the MS if the planets are separated by more than ~9 Hill radii. Most systems surviving the MS will remain stable until the WD phase, although planets scattered on to small p

The Mach number and pressure on the outlet plane of a straight micro-tube were investigated numerically for both laminar and turbulent flow cases. The numerical methodology is based on the Arbitrary-Lagrangian-Eulerian (ALE) method. The LB1 turbulence model was used for the turbulent flow case. The compressible momentum and energy equations with the assumption of the ideal gas were solved. The com

Different laser visualization techniques were applied to a pilot burner at elevated pressure using relevant liquid fuels. Special care was spent to investigate the performance of the visualization techniques when using Jet-A as fuel compared to when using Bio-Jet as fuel at gas turbine relevant conditions. The burner, a centrally placed generic injector surrounded by a swirling co-flow, was mounte

Based on observations of the rhythmic structure of L2-speech produced by L1-speakers of Albanian – which suggest the occurrence of transfer – a study is presented here that compares durational aspects between the two languages. In order to do this, speech read by Swedish and Albanian L1-speakers was recorded and investigated, and normalized durational factors were analysed. The results, however, d

Abstract in UndeterminedUzbekistan, after gaining independence from the Soviet Union in 1991, had publicly declared that it would adhere to democratic governance principles in designing and implementing its public administration policies. As a newly-independent state with democracy claims, Uzbekistan had tried to establish new democratic institutions with an effort to capture international communi

In the modified SX-700 monochromator installed at beam line I411, the focusing before the exit slit is achieved by a plane elliptical mirror. Like in the original SX-700 design, the resolution is mainly limited by the slope errors of the focusing mirror. A simple method to improve the resolution is to replace the focusing mirror by one with smaller slope errors. The effects of replacing the refocu

Increased production of autoantibodies is a characteristic feature of systemic lupus erythematosus (SLE) and there is evidence that several of these autoantibodies may contribute to the increased cardiovascular disease (CVD) in SLE. Autoantibodies against the apolipoprotein (apo) B-100 peptides p45 and p210 have been associated with a lower CVD risk in non-SLE cohorts. The aim of the present study

Radiative lifetimes of 17 excited levels of Nb i, in the energy range 27 400-47 700 cm-1 (5p y 6D degrees(9/2), 5p x 6D degrees(7/2), 5p w 4G degrees(7/2,9/2,11/2), 5s5p v 4D degrees(1/2,3/2,5/2,7/2), 5s6p n 4D degrees(1/2,3/2,5/2,7/2), 5s6p o 4F degrees(3/2,5/2,7/2,9/2)), have been measured. For 15 of these levels, the lifetimes are obtained for the first time. The lifetimes were measured using t

Variant specific zinc transporter 8 autoantibodies (ZnT8A) against either arginine (R) or tryptophan (W) at amino acid (aa) position 325 of the zinc transporter 8 (ZnT8) has been identified in T1D patients. Reciprocal cross-over tests revealed differences in half-maximal binding to indicate variable affinity of patient ZnT8 autoantibodies. Insufficient recombinant ZnT8 variant proteins have preclu

Objectives: To assess immunohistochemical (IHC) stains differentially expressed between different types of lung cancer. Methods: We evaluated 16 different IHC stains in 209 prospectively included, surgically treated primary lung cancers, including 121 adenocarcinomas, 65 squamous cell carcinomas, 15 large-cell carcinomas, 5 adenosquamous carcinomas, 2 sarcomatoid carcinomas, and 1 small-cell carci

New knowledge in science and engineering relies increasingly on results produced by scientific software. Therefore, knowing how scientists develop and use software in their research is critical to assessing the necessity for improving current development practices and to making decisions about the future allocation of resources. To that end, this paper presents the results of a survey conducted on

Impact work-rate of a weakly damped beam with elastic two-sided amplitude constraints subject to harmonic excitation is calculated. Impact work-rate is the rate of energy dissipation to the impacting surfaces. The beam is clamped at one end and constrained by unilateral contact sites near the other end. This system was an object of a vibro-impact experiment which was analyzed in our earlier paper

Although it is generally anticipated that innovation as such leads to regional prosperity (Asheim et al. 2011) there is lack of empirical evidence that confirms the direct linkage between the innovation capabilities of regions and welfare increase. It is suggested that entrepreneurship can be seen as a missing link that helps to transfer innovations into business outcomes (Braun et al. 2012). The

The Proton Exchange Membrane (PEM) fuel cell has been investigated for a long time because it has a high power density, low emission, wide choice of fuel sources, etc. However, the performance of a stack of PEM cells degrades with respect to that of a single cell. This is mainly due to the introduction of the manifold in which supplies the reactants to individual cells. The manifold can induce an