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We are now entering a new era in protein sequence and structure annotation, with hundreds of millions of predicted protein structures made available through the AlphaFold database1. These models cover nearly all proteins that are known, including those challenging to annotate for function or putative biological role using standard homology-based approaches. In this study, we examine the extent to

Streamflow estimation is important in hydrology, especially in drought and flood-prone areas. Accurate estimation of streamflow values is crucial for the sustainable management of water resources, the development of early warning systems for disasters, and for various applications such as irrigation, hydropower production, dam sizing, and siltation management. This study developed the ANN algorith

Symptoms of obsessive–compulsive disorder are related to atypical sensory processing, particularly sensory over-responsivity, in both children and adults. In adults, obsessive–compulsive symptoms are also associated with the attenuation of access to the internal state and compensatory reliance on proxies for these states, including fixed rules and rituals. We aimed to examine the associations betw

Purpose in life, which is a central component of the eudaimonic paradigm of well-being, has been sparsely examined in adolescence. This is unfortunate as adolescence is characterised by identity development and is a key period for the onset of mental disorders. To inform future research on well-being and purpose in life in adolescents, we drew factors from several fields of research, including men

ObjectiveWe examine the impact of stepfamily exposure on the educational outcomes of children, considering factors such as age at stepfamily formation, gender of the stepparent, presence of step/half-siblings, and the stepparent's socioeconomic resources.BackgroundThe prevalence of stepfamilies across the Global North highlights the urgency of the issue. Despite a sizeable existing empirical liter

Aim: To further develop the Person-Centred Care instrument for outpatient care (PCCoc), evaluate its user-friendliness and content validity, and to explore its basic psychometric properties in various outpatient settings for adults with long-term conditions. Background: Person-centred care (PCC) has been identified as a key factor to provide high-quality care. However, there is still a lack of ins

This book explores in theory and practice how artificial intelligence (AI) intersects with and alters the city. Drawing upon a range of urban disciplines and case studies, the chapters reveal the multitude of repercussions that AI is having on urban society, urban infrastructure, urban governance, urban planning and urban sustainability.Contributors also examine how the city, far from being a pass

This paper investigates the possibility of using empirical tool life models to predict tool life in a side milling application in a medium carbon steel, C 45E. To do this, an extensive dataset containing 46 data points with different machining parameters are produced. Four different empirical models: Taylor's equation, Colding's equation and Extended Taylor both using depth of cut and feed as well

Background: Patients with severe asthma may present with characteristics representing overlapping phenotypes, making them eligible for more than one class of biologic. Our aim was to describe the profile of adult patients with severe asthma eligible for both anti-IgE and anti-IL5/5R and to compare the effectiveness of both classes of treatment in real life. Methods: This was a prospective cohort s

In vitro digestion studies often use animal digestive enzyme extracts as substitutes of human gastric and pancreatic secretions. Pancreatin from porcine origin is thus commonly used to provide relevant pancreatic enzymes such as proteases, amylase and lipase. Rabbit gastric extracts (RGE) have been recently introduced to provide gastric lipase in addition to pepsin. Before preparing simulated gast

This paper explores the law and policy related to the identification, assessment, and recording of the statelessness of refugees in the Swedish asylum procedure. It considers the gaps in law and policy that can lead to a stateless refugee remaining in a prolonged, or potentially, indefinite stateless situation and the impacts of the temporary asylum law introduced in 2016. The temporary law can be

Case C-372/19 Belgische Vereniging van Auteurs, Componisten en Uitgevers CVBA (SABAM) v Weareone.World BVBA and Wecandance NV, Judgment of the Court of Justice of the European Union (Fifth Chamber) of 25 November 2020 The most recent excessive pricing case considered by Court of Justice of European Union (CJEU) revolved around fees imposed by a national royalty collective society (SABAM) on two Be

This book invites you to embark on a journey of discovery, where words become the palette for the expression of design. Furthermore, this book extends its utility to individuals working with Al and text-to-image creation. By enhancing the effectiveness of prompts, it empowers Al systems like Stable Diffusion, DALL-E, and MidJourney to produce refined and contextually relevant visual outputs. The t

During the Swedish-Russian Tundra Ecology -94 expedition one of the goals was to describe the local population fluctuations of Siberian lemmings over the Eurasian tundra. In order to compensate for the lack of repeated sampling, we used 4 different estimates to determine the phase position of the lemming populations at the different sites: i) the number of lemmings trapped per unit time; ii) the a

Context. The abundances of the α-elements are key for understanding the early chemical enrichment of the Galactic bulge. The elements of interest present lines in different wavelength regions, and some of them show lines only in part of the spectra. In the present work, the CNO trio, the a-elements Mg, Si, Ca, and Ti, and odd-Z Na and Al are examined as measured from optical and H-band lines. Aims

In this work we consider superconductor-semiconductor hybrids containing both trivial and Majorana zero modes and explore their signatures in the Majorana polarization. In particular, we consider trivial zero-energy states due to confinement and disorder, which seem to be very likely experimental scenarios. We show that the Majorana polarization is able to characterize the topological phase transi