Filetype
After an initial clarification of the notion of the risk, a brief discussion of the distinction between testing and screening, and of the difficulties of defining genetic information in a precise way follows an overview of public concerns raised by genetic testing and screening. Next section reviews various types of ethical issues in this context. The challenges are not the same for all types and
This paper deals with noise suppression in multichannel measurements, using a certain signal model but without assuming stationarity of the signals involved. This enables application to signals whose spectral characteristics are time-variable. The novelty consists of an algorithm for obtaining an approximation of the Wiener filter for each channel. The filters are computed using the Weyl transform
Typhoon Haiyan hit the Philippines on 8th November 2013 destroying more than 1 million houses and affecting mostly the poor. This paper discusses user involvement in housing recovery from a capability perspective. The paper also analyses possibilities for extension of the housing solutions. Based on the Sphere handbook and the theoretical framework, a Model for user involvement in evolutionary hou
Background: Radiostereometric analysis (RSA) studies have shown that the continuous migration of tibial components is predictive of aseptic loosening following total knee arthroplasty (TKA). In the present study, we investigated whether accurate sizing and placement of tibial components are related to the degree of implant migration as measured with use of RSA.Methods:A total of 111 patients who u
Drought has negative impacts on water resources, food security, soil degradation, desertification and agricultural productivity. The meteorological and hydrological droughts prediction using standardized precipitation/runoff indices (SPI/SRI) is crucial for effective water resource management. In this study, we suggest ANFISWCA, an adaptive neuro-fuzzy inference system (ANFIS) optimized by the wat
GPUs in embedded platforms are reaching performance levels comparable to desktop hardware, thus it becomes interesting to apply Computer Vision techniques. We propose, implement, and evaluate a novel feature detector and descriptor combination, i.e., we combine the Harris-Hessian detector with the FREAK binary descriptor. The implementation is done in OpenCL, and we evaluate the execution time and
Sequencing of immunoglobulin germline gene loci is a challenging process, e.g. due to their repetitiveness and complexity, hence limiting the insight in the germline gene repertoire of humans and other species. Through next generation sequencing technology, it is possible to generate immunoglobulin transcript data sets large enough to computationally infer the germline genes from which the transcr
Environmental, social and governance (ESG) issues are driving corporate strategy and performance. However, does this mean more ESG reporting is being done? If so, is the quality of ESG reports improving? And what about ESG performance? In this paper, we examine these three trends in ESG reporting—quantity, quality and corporate ESG performance. With a Swedish multinational corporate focus, we anal
This chapter argues for a new listening practice for electroacoustic music (EAM) that I call “deep situated listening”. “Deep situated listening” builds on existing EAM-theories, aesthetics and practices – which I here collectively refer to as the “hearing heads” approach – but extends this approach by adding an explicitly feminist perspective. “Deep situated listening” combines Donna Haraway’s no
Pointing is a typical means of directing a human's attention to a specific object or event. Robot pointing behaviours that direct the attention of humans are critical for human-robot interaction, communication and collaboration. In this paper, we describe an experiment undertaken to investigate human comprehension of a humanoid robot's pointing behaviour. We programmed a NAO robot to point to mark
Synthesis of nanocomposites based on the low density polyethylene (LDPE) with homogeneous dispersion of CeO2 nanoparticles is reported.
Background The implementation of immunological biomarkers for radiotherapy (RT) individualization in breast cancer requires consideration of tumor-intrinsic factors. This study aimed to investigate whether the integration of histological grade, tumor-infiltrating lymphocytes (TILs), programmed cell death protein-1 (PD-1), and programmed death ligand-1 (PD-L1) can identify tumors with aggressive ch
The formation and evolution of galaxies have proved sensitive to the inclusion of stellar feedback, which is therefore crucial to any successful galaxy model. We present INFERNO, a new model for hydrodynamic simulations of galaxies, which incorporates resolved stellar objects with star-by-star calculations of when and where the injection of enriched material, momentum, and energy takes place. INFE
Histidine is a key amino-acid residue in proteins with unique properties engendered by its imidazole side chain that can exist in three different states: two different neutral tautomeric forms and a protonated, positively charged one with a pKa value close to physiological pH. Commonly, two or all three states coexist and interchange rapidly, enabling histidine to act as both donor and acceptor of
