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We present the results of multiple simulations of open clusters, modelling the dynamics of a population of brown dwarf members. We consider the effects of a large range of primordial binary populations, including the possibilities of having brown dwarf members contained within a binary system. We also examine the effects of various cluster diameters and masses. Our examination of a population of w
When Axel Oxenstierna, Chancellor of Sweden, died in 1654, Sweden was a great power. In 1612, however, when Oxenstierna took office, Sweden was on the verge of collapse. In the east, she was menaced by Muscovy, in the south-east by Poland, and in the west by Denmark. One of the means to save the Swedish realm was through active diplomacy. Two important figures in Oxenstierna’s diplomatic network w
In the present study, the heat transfer characteristics on the suction and pressure sides of an outlet guide vane (OGV) are investigated by using liquid crystal thermography (LCT) method in a linear cascade. Because the OGV has a complex curved surface, it is necessary to calibrate the LCT by taking into account the effect of viewing angles of the camera. Based on the calibration results, heat tra
The walking tests with a thermal manikin TORE were carried out with THERMPROTECT WP2 clothing. The test conditions simulated the human tests of the same work package, including ambient conditions (10 and 25 °C), clothing (impermeable and permeable), wetting of cotton underwear (wet and dry) and setting the walking speed to approximately the same level. Additional tests in homogenous conditions (Ta
The present study concerns the application of a large eddy simulation (LES) model, capable of dealing with chemical reactions described by multistep reaction mechanisms and thermal radiation. The LES model, based on prefiltering of the balance equations of mass, momentum, and energy contains a variety of submodels far representing the residual stress tensor and flux vectors and the filtered reacti
Members of the transforming growth factor (TGF)-beta family play pivotal roles in the control of differentiation, proliferation and tolerance in peripheral T cells. Recently, they have been implicated in thymic selection, but their role is so far not well characterized. In the present study, we demonstrate that specific thymocyte populations are under the influence of either the TGF-beta and/or Ac
We discuss the age of the stellar disks in the solar neighborhood. After reviewing the various methods for age dating, we discuss current estimates of the ages of both the thin- and the thick disks. We present preliminary results for kineymatically-selected stars that belong to the thin- as well as the thick disk. All of these dwarf and sub-giant stars have been studied spectroscopically and we ha
BACKGROUND: Symptoms from throat (sensation of globus; frequent throat clearing; irritated throat) are common in patients referred to voice clinics and to ENT specialists. The relation to symptoms of voice discomfort is unclear and in some cases patients do not have voice problems at all. Instruments for patients' self-reporting of symptoms, and assessment of handicap, such as the Voice Handicap I
The Wnt signaling pathway is essential in regulating various cellular processes. Different mechanisms of inhibition for Wnt signaling have been proposed. Besides β-catenin degradation through the proteasome, nemo-like kinase (NLK) is another molecule that is known to negatively regulate Wnt signaling. However, the mechanism by which NLK mediates the inhibition of Wnt signaling was not known. In th
This work aims to investigate the effect of liquid entrainment on liquid film dryout in annular flow for flow boiling. Entrainment and deposition rates of droplets were included in mass conservation equations to estimate the local liquid film mass flux in annular flow, and the critical vapor quality at dryout conditions. Different entrainment rate correlations were evaluated using flow boiling dat
We present an iterative retrieval algorithm based on data constraint for ultrashort pulse characterization using dispersion scan (d-scan). The proposed algorithm is much faster and leads to a drastic reduction of retrieval times, but, compared to the standard algorithm, it performs less robustly in the retrieval of noisy d-scan traces. The algorithm is tested on several simulated cases and in two
SOX9 is a transcription factor of the SRY family that regulates sex determination, cartilage development and numerous other developmental events. In the foetal growth plate, Sox9 is highly expressed in chondrocytes of the proliferating and prehypertrophic zone but declines abruptly in the hypertrophic zone, suggesting that Sox9 downregulation in hypertrophic chondrocytes might be a necessary step
We analyze the convergence rate of the Dirichlet-Neumann iteration for the fully discretized unsteady transmission problem. Specifically, we consider the coupling of two linear heat equations on two identical non overlapping domains with jumps in the material coefficients across these. In this context, we derive the iteration matrix of the coupled problem. In the 1D case, the spectral radius of th
The most important goals for the field of immuno-oncology are to improve the response rate and increase the number of tumor indications that respond to immunotherapy, without increasing adverse side effects. One approach to achieve these goals is to use tumor-directed immunotherapy, i.e., to focus the immune activation to the most relevant part of the immune system. This may improve anti-tumor eff
Laser-induced incandescence (LII), elastic light scattering (ELS) and extinction were used to investigate the early stages of soot formation when seeding metal salts at various concentrations into a premixed ethylene/air flame on a PerkinElmer burner. The investigation contained seven salts, where we in this work mainly focus on two of these salts, potassium chloride (KCl) and iron chloride (FeCl3
For the first time, laser-induced thermal grating spectroscopy (LITGS) in the spectral range around 3. μm is demonstrated as a versatile diagnostic tool. This spectral region is of particular interest in combustion diagnostics as many relevant species such as hydrocarbons and water exhibit fundamental vibrational modes and hence can be probed with high sensitivity. Another benefit of the IR-LITGS
Short leukocyte telomere length (LTL) may be associated with several psychiatric disorders, including major depressive disorder (MDD). Short LTL has previously been associated with poor response to psychiatric medications in bipolar disorder and schizophrenia, but no studies have prospectively assessed the relationship of LTL to SSRI response in MDD. We assessed pre-treatment LTL, depression sever
