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Single-cell transcriptional and functional analysis of dopaminergic neurons in organoid-like cultures derived from human fetal midbrain

Significant efforts are ongoing to develop refined differentiation protocols to generate midbrain dopamine (DA) neurons from pluripotent stem cells (PSCs) for application in disease modeling, diagnostics, drug screening, and cell-based therapies for Parkinson's Disease (PD). An increased understanding of the timing and molecular mechanisms promoting the generation of distinct subtypes of human mid

Phonetic and Phonological Variation in Vowel Discrimination Performance : Effect of Swedish Vowel Categories and Dialects

Acoustic discrimination of speech sounds is affected by various factors, ranging from more universal acoustic properties of categories to the phoneme systems of the native language and dialect, and even influences from languages learned later in life. A discrimination experiment containing East Central Swedish vowels was carried out with 30 native Swedish listeners in order to explore the variatio

Notorietet – en rättsosäker gråzon? - Om rättens hantering av notoriska fakta med hjälp av materiell processledning och ordböcker i ljuset av Snippadomen

I den så kallade Snippadomen frikände Hovrätten för Västra Sverige den tilltalade från åtal om våldtäkt mot barn då målsägandens ordanvändning, bestående i ordet ”snippa”, inte ansågs ge stöd för att en penetration av målsägandens underliv ägt rum. Hovrätten hade inte diskuterat ordets betydelse med parterna under huvudförhandlingen, utan förlitade sig i slutändan på en ordboksdefinition för att uIn the so-called Snippa verdict, the Court of Appeal for Western Sweden acquitted the defendant of the charge of child rape, due to the judges’ uncertainty of the victim’s use of the word “snippa”. The Court of Appeal had not discussed the meaning of the word with the parties during the trial and ultimately relied on a dictionary definition to determine the meaning of the word, which did not suppo

Courage, Chivalry and Control: A Thematic Analysis of the Depiction of Soldiers in the Swedish Armed Forces and the United States Armed Forces

This essay aims to analyze the depiction of an ideal soldier in order to research whether these depictions perpetuate values and ideals found in the theoretical framework of militarized masculinity and the logic of masculinist protection. The selected material consists of official documents from both the Swedish Armed Forces as well as the United States Armed Forces, which will be analyzed through

The Use of Indirect Force in Contemporary Conflicts - An analysis of state support to non-state actors and the legacy of the Nicaragua judgement

Denna uppsats undersöker när, och vilken typ av, statligt stöd, till icke-statliga aktörer, utgör ett brott mot våldsförbudet enligt artikel 2(4) i FN-stadgan, med Nicaragua-domen som utgångspunkt. Internationella domstolen fastställde att beväpnande och utbildning av icke-statliga väpnade grupper utgör ett brott mot våldsförbudet, medan finansiellt och, vissa typer av, logistiskt stöd i regel falThis thesis examines when, and what type of, state support to non-state actors constitutes a breach of the prohibition on the use of force under Article 2(4), using the Nicaragua judgement as a central reference point. The ICJ established that arming and training non-state armed groups amount to an unlawful use of force, while financial and some forms of logistical support generally fall under the

Psaltarpsalmen i Svenska kyrkans gudstjänstliv

During the second half of the 20th century, more possibilities of singing Psalms in the common Sunday service arose in Church of Sweden. The aim of this study is to see in what different ways the Psalms are usually sung and where they appear in the different worship books. I am interested in how this has changed over time, from the 1940s until today. A special focus is also on church musicians and

Incentives and actions of a transitioning industry

This thesis seeks to investigate the role of the Sustainable Development Goals (SDGs), the Paris Agreement, and the Swedish Climate Act in the transition to net-zero in energy intensive industries, with a focus on the steel sector. Several empirical studies have previously been done on both national and international policies and how they influence low-carbon transitions and technological innovati

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With the advancement in autonomous driving technology, the shape of vehicle seats is expected to change. Against this backdrop, a study is required to verify whether or not the diversely-changing seat arrangements are appropriate from the emotional perspective of the driver. This study set the first-row passenger scat with an adjustable seatback, such as an upright position, a 15-degree rotation,

Introduction : Transnational Fascism

For many years, fascism in East Central and Southeastern Europe remained an overlooked aspect of the history of transnational and transatlantic fascism. This introduction provides a background on how this came to pass and why we should rethink this assumption. The introduction explains how the heterogeneity of East Central and Southeastern European fascism alters the general understanding of Europ

The cosmic journey of dust grains – from nucleation to planetary system

Dust is essential to the evolution of galaxies and drives the formation of planetary systems. The challenge of inferring the origin of different pre-solar dust grains from meteoritic samples motivates forward modelling to understand the contributions of low- and high-mass stars to dust in our Solar system. In this work we follow the evolution of dust with tracer particles within a hydrodynamical s

Some issues of accessibility in online social services: direct access versus signposting

Easy and low-threshold access is considered to be a major advantage of online services. In Sweden, social services in several municipalities strive to increase their accessibility by responding to anonymous users online. This paper raises the question about the nature of accessibility that the online social services entail. Two online platforms were studied: synchronous online chats and asynchrono

De avtalade och lagstadgade begränsningarna av arbetstagarnas frihet – om sekretessens påverkan både inom och utom anställningsförhållandet

Uppsatsen syftar till att klargöra rättsläget avseende tystnadsplikt och huruvida lojalitetsplikt och kritikträtt samspelar, samt hur sekretessbestämmelser inverkar i rättsfrågan. Med utgångspunkt i det arbetsrättsliga förhållandet mellan arbetsgivare och arbetstagare undersöks hur lojalitets- och tystnadsplikt samt kritikrätt påverkar arbetstagarens handlingsutrymme, vilket sätts i relation till The thesis aims to clarify the legal framework regarding confidentiality and whether the duty of loyalty and the right to criticise interact, as well as how secrecy provisions affect the legal issue. Based on the employment relationship between employer and employee, the study examines how the duty of loyalty and confidentiality, as well as the right to criticise, affect the employee’s scope of ac

Firefighter exposures during structural fires : An overview of real-world data

This paper examines firefighter exposure to emissions during actual firefighting in building scenarios. The focus is on actual exposure, not small-scale lab tests, to identify research gaps in light of the International Agency for Research on Cancer (IARC) classification of firefighting as an occupation with a heightened risk for certain types of cancer. The work is based on a systematic literatur

Rätten till integritet vid bekämpning av penningtvätt - En undersökning av motstridiga krav mellan AML-regleringen och dataskyddsförordningen

Bekämpningen av penningtvätt utgör ett centralt samhällsintresse inom Europeiska unionen och har gett upphov till ett omfattande regelverk som ställer långtgående krav på att verksamhetsutövare behandlar och lagrar personuppgifter. Samtidigt har skyddet för den personliga integriteten stärkts genom EU:s allmänna dataskyddsförordning (GDPR). Regelverken är inte direkt motstridiga, men förutsätter eThe fight against money laundering constitutes a central public interest within the European Union and has resulted in an extensive regulatory framework imposing far-reaching obligations on obliged entities to process and retain personal data. At the same time, the protection of personal privacy has been strengthened through the EU General Data Protection Regulation (GDPR). Although these regulato

The decreasing availability of reindeer forage in boreal forests during snow cover periods: A Sámi pastoral landscape perspective in Sweden

This paper argues that Sámi reindeer pastoralism in Sweden is highly stressed during the critical snow cover periods due to large-scale human interventions, especially forestry, and that these have over time significantly worsened the ecological conditions for natural grazing-based responses to changing snow conditions caused by climate change. Informed by a literature review, the paper conceptual

There is no place like home : home satisfaction and customer satisfaction in online grocery retailing

This study acknowledges that home is a central and valenced place for most people, and therefore it is assumed that (a) the content in people’s general category for home issues can be activated easily, particularly by various home-related stimuli, and that (b) the affective charge of such content can have a valence-congruent impact on evaluations of home-related stimuli. These assumptions were the

Divine Sovereignty and Clerical Authority in Early Shi‘i Islamism : Bāqir al-Ṣadr (1935–80) and Taqī al-Mudarrisī (b. 1945) on the Islamic State

Divine sovereignty (ḥākimiyya)—as conceived by Abū al-A‘lā Mawdūdī (1903–79) and popularised by Sayyid Quṭb (1906–66) - has been a central component of Islamist thought. This article investigates the reception of the concept within Shi‘i Islam. As case studies, the article choses two prominent actors in the formative period of Shi‘i Islamism in Iraq: Muḥammad Bāqir al-Ṣadr (1935–80) and Muḥammad T

Methods for Analysing Steering Effects of Global Goals

This chapter provides an overview of the multi-faceted landscape of methods used to study the steering effects of the Sustainable Development Goals. After a discussion of the political use of science and the complex relations between science and politics, the chapter showcases a selection of different methods that are employed to trace the steering effects of the Sustainable Development Goals. Sel