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Purpose: To assess the ability of quantitative pupillometry [using the Neurological Pupil index (NPi)] to predict an unfavorable neurological outcome after cardiac arrest (CA). Methods: We performed a prospective international multicenter study (10 centers) in adult comatose CA patients. Quantitative NPi and standard manual pupillary light reflex (sPLR)—blinded to clinicians and outcome assessors—

Patients with cold urticaria can after exposure to cold air or infusions react with hypotension and cardiovascular collapse. We here report on a patient having a severe cold urticaria who because of angina required myocardial revascularization: She was successfully operated in normothermic cardiopulmonary bypass with cardioplegia.

In a Swedish sample of persons eligible for disability services and aged 55 years or older in 2012, persons (n = 601) with autism spectrum disorder diagnoses registered in specialist care were identified. Register data concerning diagnoses of other psychiatric disorders, psychiatric care, and psychiatric medication were reviewed. More than 60% had been in contact with psychiatric care. The majorit

The response of a tree trunk to a hammer blow, measured by sensors positioned around the excited cross section, consists of two kinds of transient mechanical waves: longitudinal P- and transverse S-waves. The aim of this paper is to extract the velocity of the S-waves, using a filtering structure that emphasizes the waves heading in one of the directions along the circumference. By this approach,

Modern wind turbines are designed to withstand approximately for a lifetime of 20 years [1]. However, a very long design life of 100 years or more can be expected for high-quality concrete foundations. Thus there is a big difference in lifetime between wind turbines and foundations. There is a significant economic benefit of replacing the out-of-date wind turbine with a new turbine of better power

This paper discusses the existence and scope of the morality exception from patentability, in Article 53 (a) of the European Patent Convention. The analysis will look into the history of the provision, debate its rational and interpretation by reference to three examples of technology areas: stem cell research; gene editing and AI/big data analytics.Bioscience innovation has always generated heate

Nonuniform sampling (NUS) of multidimensional NMR data offers significant time savings while improving spectral resolution or increasing sensitivity per unit time. However, NUS has not been widely used for quantitative analysis because of the nonlinearity of most methods used to model NUS data, which leads to problems in estimating signal intensities, relaxation rate constants, and their error bou

An N-body code containing live stellar evolution through combination of the software packages nbody6 and stars is presented. Operational details of the two codes are outlined and the changes that have been made to combine them discussed. We have computed the evolution of clusters of 104 stars using the combined code and we compare the results with those obtained using nbody6 and the synthetic stel

There is an apparent dichotomy between the metal-poor ([Fe/H] ≤ -2) yet carbon-normal giants and their carbon-rich counterparts. The former undergo significant depletion of carbon on the red giant branch after they have undergone first dredge-up, whereas the latter do not appear to experience significant depletion. We investigate this in the context that the extra mixing occurs via the thermohalin

The utility of mRNA and protein determinations of G protein-coupled receptor 35, that is, GPR35a (GPR35 V1) and GPR35b (GPR35 V2/3), as indicators of outcome for colon cancer patients after curative surgery was investigated. Expression levels of V1 and V2/3 GPR35, carcinoembryonic antigen and CXCL17 mRNAs were assessed in primary tumours and regional lymph nodes of 121 colon cancer patients (stage

Introduction: Contact allergy to nickel (Ni) is a delayed-type hypersensitivity reaction mediated by Ni-reactive T cells producing the hallmark cytokines of several T-helper cell (Th) populations including IFN-γ(Th1), IL-4, IL-5 and IL-13 (Th2), and IL-17A (Th17). IL-22-expressing CD4+ cells, which could be either Th17 co-expressing IL-22 or Th22, expressing IL-22 in the absence of IL-17A, have al

The Tiber constituted a fundamental axis of transport and trade to Rome that made possible its subsistence and development in antiquity. However, different trajectories of research in the upper/middle and lower Tiber valley have led to an apparent perception of both stretches playing different roles in the supply of Rome, a perception not supported by wider archaeological evidence.This chapter exp

The paper discusses how families affected by Typhoon Haiyan have been involved in housing reconstruction in the Philippines and the potential for the use of medium-rise buildings. Case study methodology was conducted based on data collected three months after Typhoon Haiyan. Reconstruction projects show different degrees of users involvement such as “reparation of previous makeshift shelter,”“shel

Forty-two chapters have been structured according to the toxicities in cancer entities, and the late effects and follow-up proposals have been discussed by European and American authors. Cancer diseases in children, adolescents and young adults are treated within specific treatment protocols and can produce different late effects that will have to be cared for by specific follow-up recommendations