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Tumor cells pose a challenge to the adaptive immune system, and its key cell types, T and B cells, have frequently been associated with an improved prognosis. The success of immune checkpoint blockade has confirmed the relevance of T cells. However, the role of B cells is increasingly recognized, and highlighted in this review. Recent data suggest that tumors contain a diverse set of B cells refle

In all times, societies have known social hierarchies and boundaries between individuals and groups with distinct social characteristics. The extent to which such hierarchies and boundaries are consequential for life outcomes and persist over time differs between societies. These changes over generations in the social structure, and the social, economical, and institutional developments that shape

Family doctors and general practitioners (GPs) are the frontline in the management of fatty liver disease. With its high prevalence and strong association with other conditions commonly treated in primary care, the voice of family doctors and GPs has an important role in informing the discussion on the redefinition of fatty liver disease. Primary care uptake of any proposed name will be hampered i

Interventional cytology was first introduced in Sweden in the late 1940ies by Sixten Franzén at the Karolinska University Hospital in Solna, Stockholm. In the early 1950ies, Nils Söderström started using the technique at the University Hospital in Lund. Cytology was successively established as common practice at the pathology departments in Sweden, and e.g. Solna and Lund today have a high rate of

Organizational anticipation involves the ability to foresee and analyze potential threats and disturbances as a means to minimize the likelihood of hazard occurrence and to reduce the potential impacts. Common methods include Risk and Vulnerability Assessments (RVAs) and contingency planning, where potentially harmful events are identified and analyzed, and where measures to prevent, respond to an

BACKGROUND: The Oesophago-Gastric Anastomosis Audit (OGAA) is an international collaborative group set up to study anastomotic leak outcomes after oesophagectomy for cancer. This Delphi study aimed to prioritize future research areas of unmet clinical need in RCTs to reduce anastomotic leaks.METHODS: A modified Delphi process was overseen by the OGAA committee, national leads, and engaged clinicia

Adiabatic laminar burning velocities and post-flame NO concentrations for flat, non-stretched, premixed C2 H 4 /air flames were experimentally determined with a heat flux burner of improved design, over equivalence ratios ranging from 0.7 to 2, at atmospheric pressure and initial temperature of 298 K. Recognizing that C2 H 4 is a main intermediate in high-temperature oxidation pathways of heavy hy

Soils are continuously exposed to cycles of drying and rewetting (D/RW), which drive pronounced fluctuations in soil carbon (C) fluxes. These C dynamics are characterized by a decoupled behavior between microbial biomass synthesis (growth) and CO2 production (respiration). In general, respiration rates peak shortly after RW and subsequently decrease, while the growth peaks lag several hours behind

Background Tuberculosis is among the leading causes of death among infectious diseases. Regions with a high incidence of tuberculosis, such as sub-Saharan Africa, are disproportionately burdened by stillbirth and other pregnancy complications. Active tuberculosis increases the risk of pregnancy complications, but the association between latent tuberculosis infection (LTBI) and pregnancy outcomes i

The aim of this thesis is to examine the current VAT treatment of public bodies in the EU, as defined by the rules of the VAT Directive. This study will examine and evaluate the current problems in interpretation of Art.13 of the VAT Directive and related rules and assess in specific whether the Court’s interposition has been successful in dealing with problems arising from it, or whether more fun

Purpose: The purpose of this thesis is to develop an understanding of the way in which a brand is developed in a dyadic relationship with an external stakeholder. Theoretical: This thesis bases its theoretical framework on two main theoretical fields: Actor-Network Theory and dialectics. Methodology: The thesis is an explorative qualitative study espousing an interpretivist view of the social wo

Syftet med denna kandidatuppsats är att genom en enkätundersökning tillföra ett explicit kunskapsbidrag huruvida konsumenter bygger lojalitet till ett varumärke eller till en influencer och undersöka om det finns några skillnader i graden av lojalitet mellan generation X och generation Y. Författarna av denna kandidatuppsats har utifrån en objektivistisk ståndpunkt genomfört en kvantitativ studie The purpose of this candidate thesis is to provide an explicit knowledge of whether a consumer builds loyalty to a brand or an influencer and investigates whether there are any differences in the degree of loyalty between generation X and generation Y. The authors of this bachelor thesis have conducted a quantitative study with a deductive research based on an objectivist approach. The analysis an

Examensarbetets titel: "Influencer Marketing - ytlig inspiration eller något djupare?" - En kvalitativ studie om relationen mellan modeinfluencers och följare ur ett konsumentkulturperspektiv Seminariedatum: 2018-01-11 Kurs: FEKH29, Examensarbete kandidatnivå i marknadsföring, 15 hp Författare: Michelle Da Silva Pereira, Eric Larsson, Oscar Molin Handledare: Jon Bertilsson Fem nyckeTitle: "Influencer Marketing - Superficial Inspiriation or Something Deeper?" - A qualitative research about the relationship between fashion influencers and their followers from a Consumer Culture Perspective Seminar date: 2018-01-11 Course: FEKH29, Business Administration: Bachelor Degree Project In Marketing Undergraduate Level, 15 Credits Authors: Michelle Da Silva Pereira, Eric

The Nuremberg Charter introduced corporate criminal liability into international law and the great American Chief Prosecutor Justice Robert Jackson gave a promise that any legal person who commits crimes prescribed by international law shall be prosecuted and punished according to international criminal law. However, during this period of time, a corporation was never prosecuted per se as the sitt

Denna uppsats behandlar den fria rörligheten för varor i relation till det svenska alkoholmonopolet. Vidare ligger fokus på Systembolaget och dess framtid om gårdsförsäljning av alkoholdrycker blir tillåtet i Sverige. De bestämmelser som är relevanta i uppsatsens undersökning är artiklarna 34, 36 och 37 FEUF. De frågeställningar som uppsatsen följaktligen syftar till att besvara är för det första This paper deals with the free movement of goods in relation to the Swedish alcohol monopoly. Furthermore, the focus is on Systembolaget and its future if farm sales of alcoholic beverages is allowed in Sweden. The provisions relevant to the essay's examination are Articles 34, 36 and 37 TFEU. The questions that the paper thus aims to answer are firstly how articles 34 and 37 relate to each ot

Omkring 10% av Sveriges befolkning lider av kronisk njursjukdom. För de flesta patienter med långt gången, så kallad terminal njursjukdom är njurtransplantation den bästa behandlingen, både för patientens livskvalitet och ur ett hälsoekonomiskt perspektiv. Många patienter som har en villig donator passar inte med denna på grund av icke kompatibla blodgrupper eller för att de har antikroppar motBackground: For most patients with end stage renal disease (ESRD) kidney transplantation is the best treatment option. Best outcomes are achieved with living donation. To increase access to living donation for patients who are not compatible with their living donors, Kidney Exchange Programs (KEPs) have evolved. By exchanging donors, compatibility can be achieved thus enabling transplantation.

Genom en djupgående studie av de rättsmedel som gjorts tillgängliga för sökande av internationellt skydd inom ramen för Dublinsystemet och det nya migrationshanteringssystemet, utforskas i denna studie omfattningen av rättsmedlet i en situation där en medlemsstat vägrar ta ansvar för prövningen av en ansökan om internationellt skydd. Det är uppenbart att en sökande kan överklaga ett beslut om att Through an in-depth study of the remedies available to applicants for international protection under the Dublin System and the new Proposed Migration Management System, this thesis explores the scope of the remedy in the situation where a Member State refuses to take responsibility for the examination of an application for international protection. It is evident that an applicant may challenge a d

This thesis adds to the social debate on the relationship between society and fashion consumers. In order to explore this, the phenomenon of fashion rental is investigated to provide insights on how fashion consumers account for their behavior in order to come off as respectable. The study takes an qualitative approach by conducting eight semi-structured interviews and exploring the participants i