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Air Pollution and Dementia : Evidence from Epidemiological Studies

This chapter reviews the growing body of epidemiological evidence linking long-term exposure to ambient air pollution with increased risk of dementia, including Alzheimer’s disease (AD) and vascular dementia (VaD). With air pollution now recognized as a potentially modifiable risk factor, the chapter explores mechanistic pathways, such as neuroinflammation and oxidative stress, through which pollu

Plasma Alkylresorcinols is an objective biomarker for gluten intake in young children

BackgroundAlkylresorcinols are a well-established biomarker for whole grain intake. There is evidence suggesting that total plasma alkylresorcinol concentration may also be used as a biomarker for gluten intake in adults.ObjectiveThe aim of the study was to evaluate if total alkylresorcinol concentration is a valid biomarker for gluten intake in young children.MethodsNon-fasting plasma alkylresorc

Biosynthesis of selenoproteins in cultured bovine mammary cells.

The biosynthesis of selenoproteins was studied in relation to milk formation and mammary cell biology by incubating the bovine mammary cell line MAC-T with (75Se)selenite. Intracellular proteins and proteins secreted into the cell culture medium were separated by 2D electrophoresis, the selenoproteins were detected by autoradiography, and the proteins were identified by MALDI-TOF. Approximately 35

Human IgE against the major allergen Bet v 1 - defining an epitope with limited cross-reactivity between different PR-10 family proteins.

The interaction between IgE and allergen is a key event at the initiation of an allergic response, and its characteristics have substantial effects on the clinical manifestation. Despite this, the molecular details of the interaction between human IgE and the major birch allergen Bet v 1, one of the most potent tree allergens, still remain poorly investigated.

Observations of the interaction of an urban plume with cloud

Experiments were performed to examine the effects of the properties of the aerosol and trace gases in the airmassflowing into cloud on the microphysics and chemistry of the cloud and to investigate the role of the cloud in modifying the properties of the aerosol and trace gases emerging downwind of the cloud system. Measurements of the aerosol properties were made at out of the cloud sites both up

Evaluation of high temperature membrane electrode assemblies based on sulfonated polysulfones

In the development and evaluation of alternative ionomers, the membrane development and ex situ characterization have been the focus of interest. The properties of a MEA are dependent on the composition of materials in the components, i.e. membrane, electrodes and gas diffusion layers, and the interaction between these parts. The complexity of water transport in different components is one example

Empirical Observations regarding predictability in user access behavior in a distributed digital library system

Today document archives are geographically distributed but often not replicated. This can potentially result in a low quality of service in terms of reduced availability and long user-perceived access times. Instead of indiscriminate replication we study the effectiveness of caching techniques such as prefetching and selective preloading. Our technique analyzes whether user access behavior is pred

MCV and shear strength of compacted fine-grained tills

Compaction and shear strength tests have been performed on different compacted fine-grained tills. The results show that the water sensitivity of the soil is not only dependent on particle size but also on the soil's chemical composition. Comparisons between modified Proctor and the moisture condition value (MCV) show similarities between the optimum moisture content despite the differences in com

Health Claims in the EU and their Scientific Substantiation

A new Regulation on nutrition and health claims came into force in 2007 with implementation during a three-year period and will harmonise this area within the European Community. It makes provision for health claims on foods, including reduction of disease risk claims, and thus recognises the importance of food and nutrition for health. Member states have provided suggestions for claims regarding