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The article provides an overview of ongoing research and key characteristics of Cognitive Semiotics, an emerging field dedicated to the transdiciplinary study of meaning, involving above all researchers from semiotics, linguistics, developmental and comparative psychology and philosophy. The combination of the following features distinguishes it from other synthetic approaches: (a) integration of
PRELP is a member of the leucine-rich repeat family of extracellular matrix proteins in connective tissue. In contrast to other members of the family, the amino-terminal domain of PRELP has a high content of proline and positively charged amino acids. This domain has previously been shown to bind chondrocytes and to inhibit osteoclast differentiation. Here we show that PRELP mediates cell adhesion
Wear particles commonly used for experiments may carry adherent endotoxin on their surfaces, which may be responsible for the observed effects. In this study, we attached titanium plates to the tibiae of 20 rats. After osseointegration, endotoxin-contaminated or uncontaminated high-density-polyethylene (HDPE) particles were applied. Contaminated specimens showed a dramatic resorption of bone after
An increasing body of evidence suggests that a low-glycaemic-index (GI) diet has a therapeutic as well as a preventive potential in relation to the insulin resistance syndrome. The implementation of a low-GI diet, however, will require an extended list of low-GI foods to be available on the market. The tailoring of low-GI bread products offers a particular challenge due to their generally high GI
We present a simple, semi--analytical description for the final stagesof mergers of black hole (BH) -- neutron star (NS) systems. Such systemsare of much interest as gravitational wave sources and gamma--ray burstprogenitors. Numerical studies show that in general the neutron star isnot disrupted at the first phase of mass transfer. Instead, what remainsof the neutron star is left on a wider, ecce
Nuclear spin relaxation is a powerful method for studying molecular dynamics at atomic resolution. Recent methods development in biomolecular NMR spectroscopy has enabled detailed investigations of molecular dynamics that are critical for biological function, with prominent examples addressing allostery, enzyme catalysis, and protein folding. Dynamic processes with similar correlation times are of
Species of Haemoproteus (Haemosporida: Haemoproteidae), avian haemosporidians, have traditionally been described based on morphology of their gametocytes and on limited experimental information on their vertebrate host specificity. We investigated to what extent the morphological species are represented by monophyletic groups based on DNA sequence data using 2 different fragment lengths of the cyt
Twenty-three south-Swedish public supply wells were studied to assess pesticide pollution of regional groundwater resources. Relations between pesticide occurrence, hydrogeology, and land use were analyzed using Kohonen's Self-Organizing Maps approach. Pesticides are demonstrated to be substantially present in regional groundwater, with detections in 18 wells. Concentrations above the drinking wat
On the basis of a panel study in rural Tamil Nadu, some analytical and comparative studies across India, and the ARIS-REDS survey, I discuss the changing scenario of rural change, the growth of non-farm activities and income, and State interventions until the first decade of the twenty-first century. The overall conclusion is that there are strong evidences of a slow but stable growth of income wi
Popular Abstract in Swedish Chefskap och ledarskap hos sjuksköterskor i högre chefsbefattningar inom hälso- och sjukvården. I dagens hälso- och sjukvård har sjuksköterskor i chefsposition en förändrad och utökad roll, bland annat till följd av decentraliserade organisationer och utökade ansvarsområden. Utvecklingen av omvårdnaden kommer till en del att vara beroende av chefernas förmåga och skickThe aim of this thesis was to illuminate the management and leadership of nurse managers within Swedish health care organizations and to recognize influencing factors of importance for the nurse managers in exercising and developing their management. The interviewees were all active in their positions at the time of the interviews. The nurse managers served at top management levels in either execu
The dissociation of DNA-cationic surfactant complexes with the addition of a negative amphiphile was studied by fluorescence microscopy (FM). The unfolding of DNA molecules previously compacted with cationic surfactant was shown to be dependent on the anionic surfactant chain length; lower amounts of a longer-chain surfactant were needed to release DNA into solution. However, we observed no depend
