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The bi-component leukocidins of Staphylococcus aureus are important virulence factors that lyse human phagocytic cells and contribute to immune evasion. The γ-hemolysins (HlgAB and HlgCB) and Panton-Valentine leukocidin (PVL or LukSF) were shown to assemble from soluble subunits into membrane-bound oligomers on the surface of target cells, creating barrel-like pore structures that lead to cell lys

Insomnia and sleep apnea represent the most prevalent sleep disorders worldwide. Incidences are discouraging, with perhaps less attention in some parts, and the complexity in the pathophysiologies of the two diseases pose a major challenge to clinicians and researchers. Mainstream therapeutic regimens are afflicted by adverse side effects, laborious, demanding enormous amounts of money, and are in

Video on Demand (VoD) is a service that delivers video seamlessly to the consumer on demand. This thesis examines the consumers’ opinion on the different VoD services that exists on the Swedish market. To conduct our research we collected quantitative data by using a survey and then conducted a qualitative analysis. As a theoretical framework we used our own modified version of The DeLone and

The aim of this study is to contribute to the existing literature on co-creation in investigating consumers’ motives for participation on the one hand and possible effects of this participation on brand knowledge on the other. It thus provides a link between co-creation, motivation, and branding literature. A constructionist ontological stance and interpretive epistemology led us to the research p

This thesis analyses the tax treatment of foreign investment funds in the Netherlands. Investment funds subject to a special tax scheme are entitled to the reimbursement of withholding tax on the dividends they receive. In order to qualify for the special tax scheme, investment funds have to meet two requirements. The analysis in this thesis is twofold. Both the compatibility of the special tax

Targeted transgene expression in rat brain using lentiviral vectors Targeted Transgene Expression in Rat Brain Using Lentiviral Vectors Johan Jakobsson,* Cecilia Ericson, Maria Jansson, Elin Björk, and Cecilia Lundberg Wallenberg Neuroscience Center, Department of Physiological Science, Lund University, Lund, Sweden Direct gene transfer to the adult brain is dependent on vectors that transduce no

https://www.molecular-neurogenetics.lu.se/sites/molecular-neurogenetics.lu.se/files/publication_in_journal_of_neuroscience_research_0.pdf - 2026-05-19

In a working world faced with technological innovation, rampant viruses, environmental and climate change, and a volatile global political situation, agricultural workers face the continuing dual human rights dilemma of occupational health and safety and access to a healthy environment. More than a third of the world's working population is engaged in agriculture, which plays a vital role in d

For the sense of well-being and human health, a pleasant indoor environment is essential. Today, people spend about 90 % of their time indoors, meaning that they can be significantly affected by the buildings in which they spend most of their time. Older people are bound to spend more time indoors and also as they belong to the most sensitive age group, their indoor environments as elderly homes m

BACKGROUND: Wolff-Parkinson-White (WPW) syndrome is a rare cardiac disorder that predispose to supraventricular arrhythmias. Prognosis is usually benign, yet there is an increased lifetime risk of sudden death. While typically sporadic, familial clustering has been reported. This study aimed to assess the risk of WPW, arrhythmias, and mortality among siblings of individuals with WPW.METHODS: This

This essay demonstrates that the origin of modern Russian national conservatism lies in the Soviet underground anti-communist and anti-liberal movement, which developed under the strong influence of the theorists of integral traditionalism, fascism, and the Nouvelle Droite. Vladimir Putin's political ontology, based on the idea of the tragedy of Russia and Europe caused by the weakening of their s

Soma design is intimately entangled with the politics, not only of design itself, but of bodies. We combine perspectives from soma design, political theory, and Sara Ahmed’s work The Cultural Politics of Emotions, to develop five political provocations that reflect on the politics of soma design and the possibilities and frictions therein. Inspired by soma design’s roots in somaesthetic philosophy

Från och med den 1 januari 2020 skärptes straffskalan för sexköp av barn. Syftet med åtgärden var att förstärka det straffrättsliga skyddet för ungdomar mot att dras in i prostitution. Brottet är förknippat med låg åtalsfrekvens. Det har tidigare förklarats med att aktsamhetskravet i förhållande till ålder i 6 kap. 13 § BrB - som täcker flera sexualbrott med åldersgräns - var särskilt svårt att upIn January 2020 the range of punishment for exploitation of a child through the purchase of a sexual act got stricter. The reasoning behind the change was to strengthen the criminal justice protection for these children. Exploitation of a child through the purchase of a sexual act is associated with a low prosecution frequency. An explanation for this has been that the rule of negligence in the si

There is no agreement on how to classify, define or diagnose hip-related pain-a common cause of hip and groin pain in young and middle-aged active adults. This complicates the work of clinicians and researchers. The International Hip-related Pain Research Network consensus group met in November 2018 in Zurich aiming to make recommendations on how to classify, define and diagnose hip disease in you

National identity, multiculturalism and invisible norms are three conceptions focused on in this essay. They are discussed and analysed with the purpose of deepening deepen the understanding of their meaning. Further on they become instruments in a study of the Liberal Party's proposal for new politics of integration. My ambition is to distinguish signs of a Swedish national identity in this p

The idea of empowering women as a strategy for poverty alleviation, has become increasingly popular with institutions, such as the UN and the World Bank, as well as with NGO:s. Today there is not one definition of what empowerment should mean and the concept is used in many different contexts and is the stated goal of various development strategies. Therefore it is interesting to take a closer

After the tsunami disaster in December 2004 many arguments were heared that one oft the major reasons behind the poor Swedish effort connected to the evacuation and health care of the Swedish citizens in Thailand right after the incident is the Swedish model with independent government authorities. By comparing the constitution, the political decision making tradition by the ministers and the hand

The official rhetoric of American Presidents is viewed by many non-Americans as somewhat ridiculous and unduly pompous and self-righteous. Vanessa Beasley, on the other hand, has argued that the constant references to the superiority of the American nation in the rhetoric of its presidents have been required in order to keep the extremely diversified nation together. Starting from a constructivi

Since the breakdown of the Soviet Union, more than fifteen revolutionary years have passed. Estonia and Latvia have undergone a change from communist states to members of the European Union. As in so many other post-communist states corruption has been a problem. However, Estonia has since the independence had a lower degree of corruption than the neighbour country Latvia. The main purpose of

I have chosen to compare and analyse anti-Semitism on two Islamist and two neo-Nazi websites. The websites belong to Radio Islam, The Muslim Brotherhood, The National Socialist Movement and The National Socialist Front. I have used the theories of William Brustein and Walter Laqueur, which claim that the perception of the Jew and Judaism has remained more or less the same for two thousands years.

This article discusses desirable political representation within the framework of representative democracy. In the desirable representation it is the responsibility of the politician to balance authoritative decision making with responsiveness towards the voters. The article intends to make visible the ethical complexity within representative democracy. Ethically the commission to represent is fur