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Molecular basis for human aquaporin inhibition

Cancer invasion and metastasis are known to be potentiated by the expression of aquaporins (AQPs). Likewise, the expression levels of AQPs have been shown to be prognostic for survival in patients and have a role in tumor growth, edema, angiogenesis, and tumor cell migration. Thus, AQPs are key players in cancer biology and potential targets for drug development. Here, we present the single-partic

The statelessness of refugees

This chapter critically engages with a central policy norm developed by key international actors working on statelessness and refugeeness over the last three decades. This is the norm that for stateless refugees their refugeeness effectively trumps their statelessness. I term this norm, which arbitrarily separates and ranks statelessness and refugeeness, the “protection hierarchy”. This norm is in

Ectopic germinal centers in the nasal turbinates contribute to B cell immunity to intranasal viral infection and vaccination

The nasal mucosa is the first immunologically active site that respiratory viruses encounter and establishing immunity at the initial point of pathogen contact is essential for preventing viral spread. Influenza A virus (IAV) in humans preferentially replicates in the upper respiratory tract (URT) but mouse models of infection result in lower respiratory tract infection. Here, we optimize IAV inoc

Massive intein content in Anaeramoeba reveals aspects of intein mobility in eukaryotes

Inteins are self-splicing protein elements found in viruses and all three domains of life. How the DNA encoding these selfish elements spreads within and between genomes is poorly understood, particularly in eukaryotes where inteins are scarce. Here, we show that the nuclear genomes of three strains of Anaeramoeba encode between 45 and 103 inteins, in stark contrast to four found in the most inte

Evolutionary change in the construction of the nursery environment when parents are prevented from caring for their young directly

Parental care can be partitioned into traits that involve direct engagement with offspring and traits that are expressed as an extended phenotype and influence the developmental environment, such as constructing a nursery. Here, we use experimental evolution to test whether parents can evolve modifications in nursery construction when they are experimentally prevented from supplying care directly

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forskare: ellen tufvesson, david aronsson klinik/institution: lungmedicin och allergologi, lunds universitet e-post: ellen.tufvesson@med.lu.se V A D F I N N S I D I T T A N D E T A G ? 12. Spirometri Lungans huvudsakliga funktion är att uppta syre och ventilera ut koldioxid, vilket förutsätter adekvat andnings för måga. Att mäta lungfunktionen är en viktig del i diagno stiseringen av lungsjukdomar

https://www.vetenskaphalsa.se/wp-content/uploads/2011/11/ForskningensDag2011-12.pdf - 2026-05-19

Ultrafast Excited State Dynamics of 5,6-Dihydroxyindole, A Key Eumelanin Building Block: Nonradiative Decay Mechanism.

As part of a program designed to elucidate the excited state properties of key eumelanin building blocks, we report herein a study of 5,6-dihydroxyindole (DHI) in phosphate buffer at pH 3 and pH 7 using femtosecond transient absorption spectroscopy. The transient absorption changes following excitation at 266 nm were used to directly monitor relaxation of the excited states. It was found that the

Understanding and Controlling Crosstalk between Parallel Molecular Wires

Cooperative effects between molecular wires affect conduction through the wires, and studies have yet to clarify the conditions under which these effects enhance (diminish) conduction. Using a simple but general model, we attribute this crosstalk to the duality of energetic splitting and phase interference between the wires' conduction channels. In most cases, crosstalk increases (decreases) condu

Gestures, referents, and anaphoric linkage in learner varieties

This paper discusses how the gestural modality can contribute to our understanding of anaphoric linkage in learner varieties, focusing on gestural anaphoric linkage marking the introduction, maintenance, and shift of reference in story retellings by learners of French and Swedish. The comparison of gestural anaphoric linkage in native and non-native varieties reveals what appears to be a particula

Eye movements and gestures in human face-to-face interaction

Gestures are visuospatial events, meaning carriers, and social interactional phenomena. As such they constitute a particularly favourable area for investigating visual attention in a complex everyday situation under conditions of competitive processing. This chapter discusses visual attention to spontaneous gestures in human face-to-face interaction as explored with eye-tracking. Some basic fixati

Relationship between safety culture and psychosocial working environment in air traffic control

The Swedish Air Navigation Service Provider in cooperation with the University of Lund aims at developing a model for supporting continuous improvements and learning focusing on safety in air traffic control. This paper focuses on relationships between the safety culture and the psychosocial working environment. These areas were studied using questionnaires at the two main air traffic control cent

Preference Logic and Radical Interpretation: Kanger meets Davidson

This paper traces the intellectual effects of an encounter between Stig Kanger and Donald Davidson -two very different philosophers working in two seemingly unconnected areas. Their meeting in Oslo 1979 led the latter to improve his influential theory of radical interpretation and gave the former an inspiration for a rather striking paradox in preference logic. But, as we show, the paradox can be