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Time-resolved fluorescence spectroscopy is used increasingly to probe molecular motions at the aqueous interfaces of biological macromolecules and membranes. By recording the time variation of the fluorescence frequency, thermal atomic fluctuations in the vicinity of the chromophore can be probed. From such fluorescence Stokes shift (FSS) experiments, it has been inferred that water motions in the

Antibody-based microarrays are among the novel classes of rapidly evolving proteomic technologies that holds great promise in biomedicine. Miniaturized microarrays (< 1 cm(2)) can be printed with thousands of individual antibodies carrying the desired specificities, and with biological sample (e.g., an entire proteome) added, virtually any specifically bound analytes can be detected. While consumi

Immune complexes were formed in vitro with antibodies obtained from rabbits immunized with bovine serum albumin in Freund's complete (FCA) or incomplete (FIA) adjuvant. The antibodies were mixed with different amounts of antigen. Immune complexes formed at maximum precipitation proportions were efficient in complement activation, whereas immune complexes formed at antigen excess had weak complemen

In Huntington's disease (HD), cognitive symptoms and cellular dysfunction precede the onset of classical motor symptoms and neuronal death in the striatum and cortex by almost a decade. This suggests that the early cognitive deficits may be due to a cellular dysfunction rather than being a consequence of neuronal loss. Abnormalities in dendritic spines are described in HD patients and in HD animal

Employing high-resolution spectra obtained with the near-UV-sensitive detector on the Keck I HIRES, supplemented by data obtained with the McDonald Observatory 2d-coudé, we have performed a comprehensive chemical composition analysis of the bright r-process-rich metal-poor red giant star HD 221170. Analysis of 57 individual neutral and ionized species yielded abundances for a total of 46 elements

What is nationalism? When did it originate and how did it develop throughout the centuries? What types of nationalism have evolved in different sociopolitical settings and why? By addressing these questions, this entry seeks to address the key issues of the conceptualization of nationalism, followed by an analysis of its development in different structural, cultural, and political contexts. The en

Den internationella arenan domineras av stater. Staters existens är befäst i sedvanerätten genom Montevideokonventionen. Det har dock i ivern att hålla sig fast vid denna uppstått en uppfattning om att de kriterierna som krävs för att något kan anses vara en stat, också blir gällande e contrario i hänsyn till när stater ska anses upphöra att existera. En av de fyra kriterierna är kriteriet om terrThe global arena is dominated by states. The existence of a state is regulated in the Montevideo Convention on the Rights of States. There does however seem, that in the desire to follow this convention, a definitive opinion that states losing one of the criteria set up by the convention, also means losing their stateship, as a Montevideo Convention e contrario, if you will. One of these four crit

This thesis examines gender equality policies of the European Union in external affairs. The aim is to discover how the meaning and “problem” of gender (in)equality is constructed, represented, and problematized in the gender policies for external action. The study also ascertains what logics underpin the problem representations, whose voices are silenced, and what subject positions are created. E