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Experiences of a User-Centred Research Approach involving Old People in Early Phases of Design; Reflections from Furniture Manufacturers

The paper concerns the furniture industry’s increased interest in opportunities and challenges to respond to demographic shifts and to meet future senior markets. A central issue discussed is how a user-centred approach in a collaborative design research project benefited the industrial partners. The paper focuses on the perspectives of the participating furniture manufacturers. The most involved

On the semantics and syntax of Scandinavian pronouns and object shift

In this article I argue that weak pronouns in the Scandinvian languages should be analysed as functional heads expressing pure phi-features, and that these heads occur either without complements or copying phi-features expressed in the rest of the extended projection. The description is modelled on a construction in Old and Modern Icelandic, where a pronoun may identify the phi-features of a delet

Systems Analysis of the Impacts of the Great East Japan Earthquake and Tsunami on Energy Supply System in Kamaishi-City

The Great East Japan earthquake and tsunami hit coastal cities in Iwate, Miyagi and Fukushima Prefectures of Tohoku Region devastating the energy supply system in the region. Electricity and fuel shortages caused severe problems in the city of Kamaishi varying from lack of mobility, communication, heating to reduced health conditions. This paper, aims to analyze the impacts of the earthquake and t

Protein hydration dynamics in solution: a critical survey

The properties of water in biological systems have been studied for well over a century by a wide range of physical techniques, but progress has been slow and erratic. Protein hydration-the perturbation of water structure and dynamics by the protein surface-has been a particularly rich source of controversy and confusion. Our aim here is to critically examine central concepts in the description of

Self-diffusion in two- and three-dimensional powders of anisotropic domains: An NMR study of the diffusion of water in cellulose and starch

The pulsed field gradient stimulated echo NMR technique is applied to the study of water diffusion in biological porous materials (a sheet of wood cellulose fibers and a packed bed of potato starch granules) consisting of randomly oriented domains with an anisotropic supermolecular organization. Expressions are presented for the probability distribution of apparent diffusion coefficients due to tw

Evaluating the usefulness of spa typing, in comparison with pulsed-field gel electrophoresis, for epidemiological typing of methicillin-resistant Staphylococcus aureus in a low-prevalence region in Sweden 2000-2004.

Clin Microbiol InfectAbstract The usefulness of spa typing was evaluated in relation to pulsed-field gel electrophoresis (PFGE), as a tool for epidemiological typing of methicillin-resistant Staphylococcus aureus (MRSA) in a low-prevalence region in southern Sweden. Bacterial isolates from 216 MRSA cases, newly identified in 2000-2004, were studied. The isolates were obtained from infected patient

Indoleamine 2,3-dioxygenase (IDO) activity influence tumor growth in the TRAMP prostate cancer model.

BACKGROUND: Indoleamine 2,3-dioxygenase (IDO) activity has been shown to be expressed in local lymph nodes and induce immune suppression of tumor immunity. Here we analyze the effect of IDO expression on prostate tumor growth using the transgenic adenocarcinoma of mouse prostate (TRAMP) animal model. METHODS: Mice deficient in IDO expression were crossed to TRAMP mice and the time to the appearanc

Gene family clustering identifies functionally associated subsets of human in vivo blood and tonsillar dendritic cells

Human dendritic cells (DCs) are a distinct but heterogeneous lineage of APCs operating as the link between innate and adaptive immune responses, with the function to either maintain,tolerance or trigger immunity. The DC lineage consists of several subpopulations with unique phenotypes; however, their functional characteristics and transcriptional similarities remain largely unknown. To further cha

Hydration of dimethyldodecylamine-N-oxide: Enthalpy and entropy driven processes

Dimethyldodecylamine-N-oxide (DDAO) has only one polar atom that is able to interact with water. Still, this surfactant shows very hydrophilic properties: in mixtures with water, it forms normal liquid crystalline phases and micelles. Moreover, there is data in the literature indicating that the hydration of this surfactant is driven by enthalpy while other studies show that hydration of surfactan

Was it there all the time?

The complement system is old, yet it may still have something new to teach us. For many years, research has existed which shows that C3d, in addition to its established role as an adjuvant, could have an immunosuppressive activity. Being true, it suggests that a common mechanism may be used both by organisms and by their pathogens to prevent unwanted immune responses.

Monte Carlo simulations of polyion-macroion complexes. 2. Polyion length and charge density dependence

The complexation between a polyion and an oppositely charged spherical macroion in the framework of the primitive model has been studied by the use of Monte Carlo simulations. The polyion length, linear charge density, and bare persistence length are varied systematically, while the properties of the macroion are kept constant. The polyion charge to macroion charge ratio is varied between 1/4 and

Development and application of soy-protein films to reduce fat intake in deep-fried foods

A soy protein film coating was developed and evaluated to reduce fat transfer in deep-fried foods during frying. Soy protein isolate solutions (10% SPI) with 0.05% gellan gum as plasticizer cooled after being held at 80 degrees C for 20 min provided suitable films. There was a significant fat reduction (55.12(+/-6.03)%db) between fried uncoated and coated discs of doughnut mix. The same films were