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Pentadecamer-binding proteins : Definition of two independent protein-binding sites needed for functional activity

The SP6 κ-promoter pentadecamer (pd) element was found to be unable to stimulate transcription when present in one copy as the only promoter element in a minimal promoter but showed weak stimulatory activity when present as a multimer (four copies). One copy of the pd element acted synergistically with an octamer element, but not with a SP1 site, to stimulate transcription. The effect was orientat

Selling luxury : Sensory labour and communication in the perfume store

In “Selling luxury” perfume and cosmetics stores are approached as mediated physical experiences of luxury. The elusive character of smell has forced perfume brands to invoke guides to explain how their products should be experienced. These guides may be human, in the form of sales assistants, or non-human, in the form of visual marketing materials, packaging and store displays. In the context of

Measuring body temperature in birds – the effects of sensor type and placement on estimated temperature and metabolic rate

Several methods are routinely used to measure avian body temperature, but different methods vary in invasiveness. This may cause stress-induced increases in temperature and/or metabolic rate and, hence, overestimation of both parameters. Choosing an adequate temperature measurement method is therefore key to accurately characterizing an animal’s thermal and metabolic phenotype. Using great tits (P

Foreign Policy Analysis and Securitization

To what extent can securitization theory help us to engage with the puzzles and problems of foreign policy analysis (FPA)? And how can FPA scholarship contribute to the development of the assumptions of securitization? This chapter will probe these questions and attempt to demonstrate that these seemingly disparate research traditions indeed both complement and inform one another. Securitization t

Calibration procedures and data correction of ePix100 detectors at the European XFEL

The European XFEL is a research facility that delivers extremely bright and short coherent X-ray pulses of tunable energy at MHz repetition rate, providing unprecedented capabilities to conduct scientific research across multiple domains. Among the suite of deployed detectors, several ePix100 modules, belonging to the family of ePix detectors developed at SLAC, are used. These charge-integrating h

Selling and over-selling Big Science in the knowledge society

In chapter 33, Hallonsten argues that the change in the historical context of Big Science, from the Cold War to contemporary innovation driven economies, has transformed its character and raised anew the issue of its legitimization. According to Hallonsten, the promotion of Big Science projects, as a result of their uncertain epistemic and technological payoff, often entails 'overselling' marketin

Using quantum annealing to design lattice proteins

Quantum annealing has shown promise for finding solutions to difficult optimization problems, including protein folding. Recently, we used the D-Wave Advantage quantum annealer to explore the folding problem in a coarse-grained lattice model, the HP model, in which amino acids are classified into two broad groups: hydrophobic (H) and polar (P). Using a set of 22 HP sequences with up to 64 amino ac

Exploring the impact of age on the predictive power of the National Early Warning score (NEWS) 2, and long-term prognosis among patients reviewed by a Rapid Response Team : A prospective, multi-centre study

Aim: To explore the impact of age on the discriminative ability of the National Early Warning Score (NEWS) 2 in prediction of unanticipated Intensive Care Unit (ICU) admission, in-hospital cardiac arrest (IHCA) and mortality within 24 hours of Rapid Response Team (RRT) review. Furthermore, to investigate 30- and 90-day mortality, and the discriminative ability of NEWS 2 in prediction of long-term

UNHCR Refugee Zakat Fund in Bangladesh : Sustainable religious funds for stateless refugees

This chapter analyzes the UNHCR Refugee Zakat Fund and the use of Islamic Social Welfare Instruments as a tool for supporting the refugee issue. Looking at the Refugee Zakat Fund from a legal and practical perspective, the research will try to understand the experience of this international non-Muslim organization in managing religious funds for Muslim refugees. The study will address the followin

International Relations and Geo-political Approaches to Tourism

Travel and tourism have become an increasingly important sociocultural and economic phenomena in the contemporary globalized world. As an arena in which people and businesses from different countries come into contact, tourism operates within the framework of particular spatial patterns and is closely bound up with issues of foreign policy, international relations, public policy and the exercise o

Maternal and fetal haemopexin and α1-microglobulin concentrations in pre-eclamptic IVF pregnancies according to presence of corpus luteum at embryo transfer

Research questionDo pregnancies with corpus luteum show different maternal and fetal plasma concentrations of the scavenger proteins haemopexin and α1-microglobulin compared with pregnancies without corpus luteum in preeclampsia?DesignCase-control study of 160 singleton pregnancies: 54 naturally conceived, 50 by IVF after fresh embryo transfer or frozen embryo transfer (FET) in natural cycle (pres

Comparison of different radiographic methods to measure the slip angle in children with slipped capital femoral epiphysis (SCFE)

Background: The management of patients with slipped capital femoral epiphysis (SCFE) requires imaging diagnostics of good quality and accurate measurement of the degree of slippage. In Sweden, three different radiological methods are commonly used: the calcar femorale method; the Billing method; and the Head-shaft angle described by Southwick. Purpose: To evaluate whether any of the three most com

Memories of Aceh Chinese : We too remember, we too belong

This article revisits the Aceh Chinese experience during the 2004 tsunami and their lives in Aceh, shaped by the region’s distinct legal and political context. Drawing on ethnographic research, it follows the life of an Aceh Chinese woman born in a small town south of Banda Aceh, highlighting the tragedy she and her community endured during the Tsunami. Through her memories, the article takes read

Reviving a Neighbourhood in the Old City Center of The Hague - Water as a Strategic Tool for Boosting the Economic, Social, and Ecological Sustainability

Canals have always been an important part of The Netherlands and played a big role within the urban development of the cities. As many of the canals lost their functions by the 19th century, a lot were replaced with streets infrastructure. Replacing the canals with streets has affected the overall ambience of many neighbourhoods in The Netherlands. The elimination of the water element caused many