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Human metapneumovirus (hMPV) is associated with respiratory tract illness especially in young children. Two hMPV genetic lineages, A and B, and four sublineages A1, A2 and B1, B2 have been defined. Infection with hMPV occurs through membrane fusion mediated by the hMPV fusion (F) protein. In this study, the inter- and intra-patient genetic diversity of the lineage A hMPV F gene was investigated. T
OBJECTIVE - The purpose of this study was to compare the incidence of vascular lower-limb amputation (LLA) in the diabetic and nondiabetic general population. RESEARCH DESIGN AND METHODS - A population-based cohort study was conducted in a representative Swedish region. All vascular LLAs (at or proximal to the transmetatarsal level) performed from 1997 through 2006 were consecutively registered an
Popular Abstract in Swedish Till processindustrin räknar man bland annat fabriker som tillverkar papper, plast och livsmedel. I en enda fabrik kan det finnas tusentals PID-regulatorer som har till uppgift att styra storheter som tryck, flöden och temperaturer till önskade värden. PID-regulatorns roll i processindustrin har därför jämförts med den arbetsmyran har i myrstacken. Huruvida en enskild mA large process industry can have somewhere between five hundred and five thousand control loops, and PID controllers are used in 90–97% of the cases. It is well-known that only 20–30% of the controllers in the process industry are tuned satisfactorily, but with the methods available today it is considered too time-consuming to optimize each single controller. This thesis presents tools for analys
Since 1750, land-use change and fossil fuel combustion has led to a 46% increase in the atmospheric carbon dioxide (CO2) concentrations, causing global warming with substantial societal consequences. The Paris Agreement aims to limit global temperature increases to well below 2C above preindustrial levels. Increasing levels of CO2 and other greenhouse gases (GHGs), such as methane (CH4) and nitrou
The freedom of establishment is an expression of the Internal Market. On the one hand, the EU tries to strengthen the Internal Market, but on the other hand, Member States have a fear to lose their national control, making them eager to restrict the free movements granted by the Internal Market doctrine. The contradiction becomes visible in regard to the cross-border movement of companies in the E
In 1989, the General Assembly of the United Nations adopted the Convention on the Rights of the Child (CRC). The convention, whose purpose is to ensure and protect children’s rights globally, was later ratified by Sweden 1990. Thereby, the country committed itself to legally follow the articles of the convention. By conducting a descriptive case study analysis of the CRC, this text aims to invest
This essay analyzes the importance of music and dancing in Jane Austen's early novels. This is done by looking at a series of musical pastimes that were popular in the 18th century. The essay also provides an overlook of the musical period of the time.
Background The obesity epidemic has influenced pain rehabilitation clinics. To date, little is known about baseline level of physical activity (PA) in patients referred to pain rehabilitation clinics. We aimed to investigate the PA levels of patients referred to pain rehabilitation clinics and to evaluate the effect of excess weight on PA level. Methods and findings Data were obtained from the Swe
To study the association between induction and outcome among two-parous women in uncomplicated pregnancies ≥ 41+3, stratified by first labour delivery mode and conditions present at first delivery. The Swedish Medical Birth Register was used to identify 58,964 uncomplicated singleton pregnancies among women with one previous birth between 1998 and 2014. Women with any registered pregnancy complica
Clofarabine has been shown to effectively induce remission in children with refractory leukemia. We conducted a prospective trial (clinicval.trials.gov NCT01025778) to explore the use of clofarabine-based chemotherapy as a bridge-to-transplant approach. Children with refractory acute leukemia were enrolled to receive two induction courses of clofarabine, etoposide, and cyclophosphamide (CloEC). Re
Introduction: Data regarding real-world impact on cancer clinical research during COVID-19 are scarce. We analysed the impact of the COVID-19 pandemic on the conduct of paediatric cancer phase I–II trials in Europe through the experience of the Innovative Therapies for Children with Cancer (ITCC). Methods: A survey was sent to all ITCC-accredited early-phase clinical trial hospitals including ques
Aim To examine the associations between individual- and disease-related factors and the odds of reaching a clinically relevant pain reduction in people with knee and/or hip osteoarthritis (OA) who underwent a first-line self-management program. Materials and methods An observational registry-based study including people with knee (n = 18,871) and hip (n = 7,767) OA who participated in a self-manag
Denna avhandling undersöker skapandet och omvandlingen av offentliga platser i Hongkong, en stad som är genomsyrad av nyliberala ideal och som under senare år har kännetecknats av betydande försämringar när det gäller demokratiska rättigheter och friheter. Som ett resultat av den nyliberala kapitalismens expansion har kommodifieringen av det urbana rummet inte bara förvärrats utan också blivit merThis thesis explores the production and transformation of public spaces in Hong Kong, a city that is steeped in neoliberal ideals and has seen substantial deterioration in terms of democratic rights and freedoms in recent years. As a result of the expansion of neoliberal capitalism, commodification of urban space has not only exacerbated, but also become more far-reaching and indiscriminate. While
This letter presents a radio frequency front-end (RFFE) for 5G new radio (NR) receivers operating in frequency range 1 (FR1). The core of this RFFE is a synthetic fourth-order Q -enhanced RF filter employing gm -boosting, noise-canceling, capacitive cross-coupling, and forward body-biasing techniques to achieve 1.7 to 6.4 GHz operating range and 1% to 40% adjustable fractional bandwidth (FBW). The
The atmospheres of ultra hot Jupiters (UHJs) are prime targets for the detection of molecules and atoms at both low and high spectral resolution. We study the atmospheres of the UHJs WASP-121b and WASP-189b by performing 3D general circulation models (GCMs) of these planets using high temperature correlated-k opacity schemes with ultra-violet (UV) absorbing species included. The GCM results are th
Crop yield improvement during the last decades has relied on increasing the ratio of the economic organ to the total aboveground biomass, known as the harvest index (HI). In most crop models, HI is set as a parameter; this empirical approach does not consider that HI not only depends on plant genotype, but is also affected by the environment. An alternative is to simulate allocation mechanisticall
π Men hosts a transiting planet detected by the Transiting Exoplanet Survey Satellite space mission and an outer planet in a 5.7 yr orbit discovered by radial velocity (RV) surveys. We studied this system using new RV measurements taken with the HARPS spectrograph on ESO's 3.6 m telescope, as well as archival data. We constrain the stellar RV semiamplitude due to the transiting planet, π Men c, as
BACKGROUND AND PURPOSE: The main radiological finding in progressive supranuclear palsy (PSP) is reduced midbrain volume. Both qualitative (e.g., hummingbird sign) and quantitative (e.g., area measurements) markers have been noted. Recent studies have shown a similar reduction also in idiopathic normal pressure hydrocephalus (iNPH). The purpose was to investigate the reliability and accuracy of th
