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A method is presented on how to quantify the moisture conditions of nuclear concrete containment walls. The method is based on first quantifying the boundary conditions at the outer and inner surfaces and then describing the moisture fixation and moisture transport within the concrete wall. The temperature and humidity conditions of the outdoor air and of the air close to the wall surfaces are mon
Peripheral nerve (PN) isografts provide a favourable environment for axon regeneration after peripheral and central nervous system (CNS) injury, but definitive information on the extent of cellular intermixing between donor and host tissues is lacking. We wished to compare migration patterns in fresh and predegenerate PN grafts, and also compare the extent of cell migration after transplantation t
The purpose of this study was to develop a new completely automated method for the interpretation of ventilation-perfusion (V-P) lung scintigrams for the diagnosis of pulmonary embolism. A new way of extracting features, characteristic for pulmonary embolism is presented. These features are then used as input to a Support Vector Machine, which discriminates between pulmonary embolism or no embolis
Background. The Gross Motor Function Measure (GMFM) is the instrument most commonly used to measure gross motor function in children with cerebral palsy (CP). Different scoring options have been developed, and their measurement properties have been assessed. Limited information is available regarding longitudinal construct validity. Objective. The objective of this research was to study the longit
A numerical algorithm is presented for the problem of a crack along the interface of an elastic inclusion embedded in an elastic plane subjected to uniform stress at infinity. The algorithm is based on a Fredholm integral equation of the second kind and allows for fast and accurate solutions to geometries of great complexity. In an example crack opening displacement and stress intensity factors ar
Lake Poopó in Bolivia is a large, extremely shallow lake. The lake surface area is ≈3000 km2 at its spill-over level, although it could dry out at times. The lake water level varies with the regional rains and with the water inflow from the Desaguadero River. This study focuses on using and comparing three different approaches to determine the hypsographic curve for the lake. As the lake is extrem
Objective. Although partial meniscectomy is a risk factor for the development of knee osteoarthritis (OA), there is a lack of evidence that meniscal damage that is not treated with surgery would also lead to OA, suggesting that surgery itself may cause joint damage. Furthermore, meniscal damage is common. The aim of this study was to evaluate the association between meniscal damage in knees withou
The receptor tyrosine kinase c-Kit plays a critical role in hematopoiesis and gain-of-function mutations of the receptor are frequently seen in several malignancies, including acute myeloid leukemia (AML), gastrointestinal stromal tumors and testicular carcinoma. The most common mutation of c-Kit in these disorders is a substitution of the aspartic acid residue in position 816 to a valine (D816V),
Treatment of [(COD)PtCl2] with LiN(SiMe3)(2) gives [COD]PtClN(SiMe3)(2) in high yield. This product was fully characterized, including an X-ray structure. From a number of examples it is shown to be a very convenient starting material for the preparation of PXP platinum pincer complexes, giving excellent yields of the cyclometalated product under mild conditions.
An organic-aqueous two-liquid-phase partitioning system was developed to degrade high concentrations of pentachlorophenol (PCP). Dioctyl sebacate was selected among 12 non-aqueous phases as the most suitable solvent to control the delivery of PCP to the aqueous phase for being non-biodegradable and biocompatible. In shake-flask experiments, the two-phase system was able to support the removal of 1
Transfer of collagen type H (CH)-specific monoclonal antibodies induces an acute form of arthritis (collagen type H antibody-induced arthritis, CAIA) in nave mice. Arthritis was induced using a pair of monoclonal antibodies M2139 and CIIC1, binding to J1 and C1(I) epitopes of CH, respectively. Thereafter, lipopolysaccharide injection was used to increase the incidence and severity of the disease.
A new hygroscopic tandem differential mobility analyzer (H-TDMA) has been constructed at Lund University within the frameworks of the EU FP6 Infrastructure Project EUSAAR (www.eusaar.org). The aim of this coordinated H-TDMA development is to design and evaluate a new generation of H-TDMAs that are capable of conducting long term measurements of the hygroscopic growth and state of mixing of sub-mic
A multireference second-order perturbation theory using a restricted active space self-consistent field wave function as reference (RASPT2/RASSCF) is described. This model is particularly effective for cases where a chemical system requires a balanced orbital active space that is too large to be addressed by the complete active space self-consistent field model with or without second-order perturb
We have shown previously that protein kinase C (PKC) epsilon can induce neurite outgrowth independently of its catalytic activity via a region encompassing its C1 domains. In this study we aimed at identifying specific amino acids in this region crucial for induction of neurite outgrowth. Deletion studies demonstrated that only 4 amino acids N-terminal and 20 residues C-terminal of the C1 domains
Objectives: To develop evidence-based recommendations for the diagnosis of hand osteoarthritis (OA). Methods: The multidisciplinary guideline development group, representing 15 European countries, generated 10 key propositions regarding diagnosis using a Delphi consensus approach. For each recommendation, research evidence was searched for systematically. Whenever possible, the sensitivity, specif
Rotational coherent anti-Stokes Raman spectroscopy (CARS) in fuel-rich hydrocarbon flames, with a large content of hydrogen in the product gases (similar to 20%), has in previous work shown that evaluated temperatures are raised several tens of Kelvin by taking newly derived N-2-H-2 Raman line widths into account. To validate these results, in this work calibrated temperature measurements at aroun
High-precision isotope-dilution U-Pb (zircon) dating was conducted on three volcanic ash fall (bentonite) samples from the Swedish island of Gotland, and on a fourth bentonite from the West Midlands, England. Zircons from the Ireviken, Grotlingbo, Djupvik (Gotland), and Wren's Nest Hill-15 (West Midlands) bentonites yielded weighted mean Pb-206/U-238 ages of 431.83 +/- 0.23/0.67 Ma, 428.45 +/- 035
