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We aimed to conduct a narrative review of the rapid advances in knowledge regarding sun exposure and all-cause mortality. Data support the hypothesis that sun exposure avoidance is a major risk factor for all-cause mortality in adjusted analysis (age, income, education, marital status, smoking, and comorbidity). This was caused by an increased risk of death due to cardiovascular disease (CVD) and
At a time when rapidly evolving technologies, political turmoil, and the tensions inherent in multiculturalism and globalization are reshaping historical consciousness, what is the proper role for historians and their work? By way of an answer, the contributors to this volume offer up an illuminating collective meditation on the idea of ethos and its relevance for historical practice. These intell
We theoretically discuss a phenomenon that we label “efficiencyism”. Efficiencyism describes a fixation on reified tenets of efficiency without questioning its assumptions and consequences. In organization and management theory efficiency is a foundational concept, which is assumed to be vital for economic success based on the optimization of input-output ratios. Based on the logic of the Jevons P
Donald proposes that early Homo evolved mimesis as a new form of cognition. This article investigates the mimesis hypothesis in relation to the evolution of teaching. The fundamental capacities that distinguish hominin teaching from that of other animals are demonstration and pantomime. A conceptual analysis of the instructional and communicative functions of demonstration and pantomime is present
The XXL survey currently covers two 25deg2 patches with XMM observations of ∼10ks. We summarize the scientific results associated with the first release of the XXL dataset, which occurred in mid-2016. We review several arguments for increasing the survey depth to 40ks during the next decade of XMM operations. X-ray (z<2) cluster, (z<4) active galactic nuclei (AGN), and cosmic background survey sci
BACKGROUND: Widespread musculoskeletal pain (WSP) and obesity frequently co-occur and may have shared risk factors. We aimed to investigate whether four dichotomized risk factors individually or jointly increase the risk for the onset of WSP and onset of obesity.METHODS: Persons aged 34-76 years in 2004 living in Ullensaker municipality, Norway, responded to questionnaires in 2004 and 2010 (n = 15
Improved understanding of the disease mechanisms underlying type 2 diabetes (T2D) is needed, and so are new treatments.A new T2D risk variant was recently identified in ADRA2A, which encodes the α2A-adrenergic receptor. The risk allele leads to receptor overexpression in β-cells that causes increased adrenergic signaling and impaired insulin secretion. We showed that the α2A-adrenergic receptor an
The deformable templates method for track finding in high energy physics is reviewed and extended to handle multiple and secondary vertex positions. An automatized minimization method that handles different types of parametrizations is derived. It is based on the gradient descent method but modified with an explicit calculation of the natural metric. Also a simplified and more intuitive derivation
Aims: To explore and compare sensitivity and specificity for HbA1c ≥48. mmol/mol as a predictor for type 2 diabetes mellitus (T2DM) in two populations with different ethnicity and to examine the predictive value of two levels of HbA1c (≥42. mmol/mol, ≥39. mmol/mol) for prediabetes in these populations. Methods: Four cohorts were examined with an oral glucose tolerance test. (1) The MEDIM Study (n
On 10 September 1751 the Swedish botanist Pehr Osbeck visited the outskirts of Canton. On his way back into the city he was surrounded by a gang of robbers who demanded money from him. When they did not receive any money, they pelted Osbeck with large stones; it was very fortunate that he was not severely injured. One of the questions this paper discusses is what were the laws in China at that tim
Inverted pendulums are very well suited to investigate friction phenomena and friction compensation because the effects of friction are so clearly noticeable. This paper analyses the effect of friction on the Furuta pendulum. It is shown that friction in the arm drive may cause limit cycles. The limit cycles are well predicted by common friction models. It is also shown that the amplitudes of the
