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Regional differences in arachidonic acid release in rat hippocampal CA1 and CA3 regions during cerebral ischemia

Changes in the levels of arachidonic acid during ischemia in selectively vulnerable areas of the hippocampus were studied in the rat brain. Since neurons in the CA1 region are more vulnerable to ischemia than neurons in the adjacent CA3 region, the release of arachidonic acid in these two regions was measured during decapitation ischemia of 4- to 12-min duration. The concentration of free arachido

Chronic dexamethasone pretreatment aggravates ischemic neuronal necrosis

This study addresses the question of whether the cyclooxygenase inhibitors indomethacin and diclofenac and the glucocorticosteroid dexamethasone ameliorate neuronal necrosis following cerebral ischemia. In addition, since these drugs inhibit the production of prostaglandins and depress phospholipase A2 activity, respectively, the importance of free fatty acids (FFAs) on the development of ischemic

Early identification of urban locations towards soundscape analysis

Soundscape management in a city implies mitigating harmful sounds and promoting useful ones, according to their environmental, social or cultural significance and considering a more human centered paradigm. The Soundscape approach does not consider sound as a waste but a resource and its application may reach more benefits than solely noise control actions. This conception conveys an emerging para

Pluviala översvämningar i stort och smått

Urbana, pluviala översvämningar orsakar stor skada på infrastruktur, byggnader och stadslivet under och efter extremregn. I den här studien har anmälningar och rapporter från försäkringsbolag och VA-huvudmannen i Malmö, VA Syd, analyserats spatialt. Målsättningen var att få en bättre förståelse för de mekanismer som påverkar pluviala översvämningar, dvs. översvämningar från intensiva regn, ibland Urban, pluvial flooding severely effects infrastructure, buildings and urban life during and after extreme rainfall. In this study, spatial analyses of flood claims from insurance companies and the water utility company of Malmö, VA Syd, are used to better understand the mechanisms and characteristics of pluvial flooding. The same data sets are used to analyse how blue-green infrastructure impacts

Vertical nanotubes connected by a subsurface nanochannel

We have built an array of vertical nanotubes connected by a subsurface nanofluidic channel. The nanotube system is to be used for cell injections. By culturing cells on top of the nanotubes the cells will be pierced and molecules can enter the cells via the subsurface channel. Several channels can be made on the same sample and different molecules can be injected into different subpopulations of c

Luftkvalitet i överbyggda stationsmiljöer

Den pågående expansionen av järnvägstransporter, för både personresor och varutransporter, gör att den rälsbundna trafiken ökar kraftigt. I samband med att personresor och pendling med tåg och järnväg ökar sker också en expansion av antalet mer eller mindre slutna stationsmiljöer under mark. Dessa miljöer kan innebära en hälsorisk genom kombinationen av slutna utrymmen och höga halter av luftburna

The use of venous blood gas in assessing arterial acid−base and oxygenation status–an analysis of aggregated data from multiple studies evaluating the venous to arterial conversion (v-TAC) method

Background: Several methods exist to reduce the number of arterial blood gases (ABGs). One method, Roche v-TAC, has been evaluated in different patient groups. This paper aggregates data from these studies, in different patient categories using common analysis criteria. Research design and methods: We included studies evaluating v-TAC based on paired arterial and peripheral venous blood samples. B

Ett rum för de ostyrigaste och bullersammaste - eller: Var låg proban? : Del 2

Den andra av två artiklar rörande det fängelse, den s k proban, som Lunds universitet hade under den tid lärosätet ägde egen jurisdiktion över anställda och studenter. Denna andra del behandlar studentoroligheter under tidigt 1800-tal, den oklara frågan var proban var placerad under 1800-talet samt några av de sista studenterna att spärras in häri under 1830- och 1840-talen, dels för brott, dels s

Myths and legends : Changing assessment procedures and practices

Leading change in relation to assessment is a significant challenge; almost everyone in the university is a stakeholder and they may have strong and varied views about how assessment should be managed. A baseline review of assessment practices at a large, diverse, and complex university showed that the prevailing culture around assessment was equivocal and that people were fearful of large-scale c

Challenges and opportunities for regenerating lung tissue using three-dimensional lung models

Lung transplantation is currently the only option for patients with end-stage respiratory diseases, but owing to various complications and adverse effects of the treatment in combination with the increasing demand for and limited access to donor organs, new strategies are needed. Recent advances in materials science, culture techniques, cell-phenotyping and isolation techniques, bioreactor enginee

Massive MIMO for Dependable Communication

Cellulär kommunikation utvecklas ständigt; för närvarande installeras 5G-system och forskning kring 6G pågår. Tre användningsfall som diskuteras är enhanced mobile broadband (eMBB), massive machine-type communication (mMTC) och ultra-reliable low-latency communication (URLLC). För att uppfylla kraven i dessa användningsfall behövs ny teknik och en kandidat är massive multiple-input multiple-outputCellular communication is constantly evolving; currently 5G systems are being deployed and research towards 6G is ongoing. Three use cases have been discussed as enhanced mobile broadband (eMBB), massive machine-type communication (mMTC), and ultra-reliable low-latency communication (URLLC). To fulfill the requirements of these use cases, new technologies are needed and one enabler is massive mult

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Utbildningsstyrelsen har i samarbete med undervisnings- och kulturministeriet börjat utveckla rektorsutbildningarna mera målmedvetet än tidigare, i synnerhet de utbildningsprogram för läroanstalternas ledning som finansieras via programmet Kunnig (Osaava). En åtgärd som ansetts vara nödvändig som underlag för utvecklingsarbetet har varit att kartlägga olika länders praxis för utbildning av läroansThe Finnish National Board of Education, in collaboration with the Ministry of Education and Culture, has started to develop the training of rectors in a more systematic way by utilizing the funds which were allocated for the Osaava programme. One of the pre-liminary measures in this regard included a survey concerning the continuing education practices of school leaders on a worldwide basis. The

AI, Norms, Big Data, and the Law

This is an overview article regarding artificial intelligence (AI) and its potential normative implications. Technology has always had inherent normative consequences not least due to AI and the use of algorithms. There is a crucial difference between algorithms in a technical sense and from a social-science perspective. It is a question of different orders of normativity - the first related to th

SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study

Background: Preoperative SARS-CoV-2 vaccination could support safer elective surgery. Vaccine numbers are limited so this study aimed to inform their prioritization by modelling.Methods: The primary outcome was the number needed to vaccinate (NNV) to prevent one COVID-19-related death in 1 year. NNVs were based on postoperative SARS-CoV-2 rates and mortality in an international cohort study (surgi