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Metformin-induced suppression of Nemo-like kinase improves erythropoiesis in preclinical models of Diamond–Blackfan anemia through induction of miR-26a

Diamond–Blackfan anemia (DBA) results from haploinsufficiency of ribosomal protein subunits in hematopoietic progenitors in the earliest stages of committed erythropoiesis. Nemo-like kinase (NLK) is chronically hyperactivated in committed erythroid progenitors and precursors in multiple human and murine models of DBA. Inhibition of NLK activity and suppression of NLK expression both improve erythr

Short half-life of HPV16 E6 and E7 mRNAs sensitizes HPV16-positive tonsillar cancer cell line HN26 to DNA-damaging drugs

Heparan/chondroitin/dermatan sulfate primer 2-(6-hydroxynaphthyl)-O-beta-D-xylopyranoside preferentially inhibits growth of transformed cells

Xylose forms the direct carbohydrate-protein link in extra- or pericellular proteoglycans (PGs) that are substituted with either chondroitin sulfate (CS)/dermatan sulfate (DS) and/or heparan sulfate (HS). Cell surface PGs carrying HS are important regulators of cell growth. Xylose coupled to an aromatic compound can enter cells and initiate either CS/DS synthesis or both HS and CS/DS synthesis, de

β -delayed proton emission from P 26 and S 27

β decay of26Ne

Safe Spaces in Unsafe Environments-Experiences from COP26 About Hosting Inclusive Spaces for Deep Encounters and Reflection

Transdisciplinary research (TDR) seeks to involve non-academic perspectives from the start, ensuring that research draws on diverse knowledge to better address “wicked” problems. Since TDR researchers have to engage with non-academic perspectives throughout the research process, this chapter focuses on the kind of communication practices that are appropriate and effective for engaging with people

The possibility of lifestyle and biological risk markers to predict morbidity and mortality in a cohort of young men after 26 years follow-up.

Birth outcomes between 22 and 26 weeks' gestation in national population-based cohorts from Sweden, England and France

Prolonged chemotherapy impairs liver regeneration after portal vein occlusion - An audit of 26 patients.

Bicyclo[3.3.1]nonane-2,6-dione and its utilization as a core building block in supramolecular architectures

Array based characterization of a terminal deletion involving chromosome subband 15q26.2: an emerging syndrome associated with growth retardation, cardiac defects and developmental delay.

BACKGROUND: Subtelomeric regions are gene rich and deletions in these chromosomal segments have been demonstrated to account for approximately 2.5% of patients displaying mental retardation with or without association of dysmorphic features. However, cases that report de novo terminal deletions on chromosome arm 15q are rare. METHODS: In this study we present the first example of a detailed molecu

Screening of yeast species for the stereo-selective reduction of bicyclo[2.2.2]octane-2,6-dione

Genetically engineered Saccharomyces cerevisiae for kinetic resolution of racemic bicyclo[3.3.1]nonane-2,6-dione

Facile synthesis and polymerization of 2,6-difluoro-2’-sulfobenzophenone for aromatic proton conducting ionomers with pendant sulfobenzoyl groups

Vanin-1 T26I polymorphism, hypertension and cardiovascular events in two large urban-based prospective studies in Swedes.

A novel chromosomal translocation t(3;7)(q26;q21) in myeloid leukemia resulting in overexpression of EVI1

Tumor attenuation by 2(6-hydroxynaphthyl)-{beta}-D-xylopyranoside requires priming of heparan sulfate and nuclear targeting of the products.

Identification and characterization of CMP-NeuAc:GalNAc-IgA1 alpha2,6-sialyltransferase in IgA1-producing cells

Mortality and its predictive factors in participants with asthma : a 26-year follow-up

Long-term neurodevelopmental outcomes in extremely preterm infants born at 22–26 weeks gestation : a follow-up of 2–2.5 years across two Swedish national cohorts from 2004–2007 to 2014–2016