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Light chain monoclonal gammopathy of undetermined significance (LC-MGUS) is an asymptomatic precursor of multiple myeloma (MM) and related disorders defined by abnormal free light chain (FLC) testing. Recently, revised FLC reference intervals were proposed by the iStopMM study group. We evaluated their performance in a large population-based cohort. MGUS cases were identified from the Danish Lymph

Natural polymers are promising sustainable materials for diverse applications. Xylans, major components of hemicellulose, exhibit origin-dependent substitution patterns that determine their physicochemical properties. Targeted enzymatic modification of these substituents offers a mild and precise approach for tailoring the polymer's characteristics. Glucuronidases (EC 3.2.1.139) and xylan α-1,2-gl

A case-control study compared 129 men with earlier partial gastrectomy (operation during the period 1952-1961) with 216 men from a community-based population study. All were born 1910-1915 and the mean age was 72 years. Men with a previous partial gastrectomy had vertebral fractures in 19% compared with 4% (P < 0.01) in the control population. Bone mineral density (BMD) in the right calcaneus meas

This paper derives a generic model for the multiple-input multiple-output (MIMO) wireless channel. The model incorporates important effects, including i) interdependency of directions-of-arrival and directions-of-departure, ii) large delay and angle dispersion by propagation via far clusters, and iii) rank reduction of the transfer function matrix. We propose a geometry-based model that includes t

Hosts can in principle employ two different strategies to defend themselves against parasites: resistance and tolerance. Animals typically exhibit considerable genetic variation for resistance (the ability to limit parasite burden). However, little is known about whether animals can evolve tolerance (the ability to limit the damage caused by a given parasite burden). Using rodent malaria in labora

The objective of this paper is to investigate how the combustion chamber design will influence combustion parameters and emissions in a natural gas SI engine. Ten different geometries were tried on a converted Volvo TD102 engine. For the different combustion chambers emissions and the pressure in the cylinder have been measured. The pressure in the cylinder was then used in a one-zone heat-releas

Thermal radiation sometimes is the dominating heat transfer mode in combustion chambers and furnaces and therefore in the design of many relevant industrial facilities prediction of it is necessary. During previous years many research efforts in the radiative heat transfer field have originated and many methods and models from simple to complex have been developed. However, the field is still open

New strategies for prevention and treatment of type 2 diabetes (T2D) require improved insight into disease etiology. We analyzed 386,731 common single-nucleotide polymorphisms (SNPs) in 1464 patients with T2D and 1467 matched controls, each characterized for measures of glucose metabolism, lipids, obesity, and blood pressure. With collaborators (FUSION and WTCCC/UKT2D), we identified and confirmed

A non-associated plasticity theory for granular materials has been developed in Part 1 based on the concept of a characteristic stress state of vanishing incremental dilation. The model is fully three-dimensional and is defined by six material parameters: two for elastic stiffness, one for plastic stiffness, two for the shapes of yield and plastic potential surfaces and one for the dilation at fai

We present an experimental comparison of magnetoconductance fluctuations measured in the ballistic, quasiballistic, and diffusive scattering regimes of semiconductor devices. In contradiction to expectations, we show that the spectral content of the magnetoconductance fluctuations exhibits an identical fractal behavior for these scattering regimes and that this behavior is remarkably insensitive t

Two hundred apparently healthy sexually active women, 17-34 years of age, who had presented for a general health check-up at the Clinic of Dermatology and Venereology, Medical University, Plovdiv, Bulgaria, were asked about genital symptoms, sexual behaviour, contraceptive use and smoking habits, and examined for signs of genital infections. They were searched for genital chlamydial infection, gon

The use of water mist for fire extinguishment has increased rapidly in recent years. The main reason is the abandonment of halon-based extinguishing systems in favour of environmentally friendlier systems. Furthermore the use of water mist systems has spread from mainly marine applications to also include the protection of buildings. The main problem in this regard is to verify the effectiveness o

In this article we address the problem of projective reconstruction of structure and motion given only image data. In particular we investigate three novel minimal combinations of points and lines over three views, and give complete solutions and reconstruction methods for two of these cases: 'four points and three lines in three views', and 'two points and six lines in three views'. We show that

The high cost of photovoltaic modules motivates the use of reflectors to increase the electricity production. The system geometry of static low-concentrating PV systems for building-integration with parabolic aluminium reflectors was optimised for maximum annual electricity production. The optical efficiency of systems with different geometries was calculated from short-circuit current measurement

This article reports on a multiblock implementation of a general three-dimensional single-block computational fluid dynamics code, which is developed in a nonorthogonal, structured, collocated finite-volume grid system, and incorporates a range of turbulence models. The multiblock implementation is essentially block-unstructured, each block having its own local coordinate system unrelated to those